Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EL076_RS01045 Genome accession   NZ_LR134275
Coordinates   176154..176903 (+) Length   249 a.a.
NCBI ID   WP_126428939.1    Uniprot ID   -
Organism   Streptococcus vestibularis strain NCTC12167     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 171154..181903
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL076_RS01025 (NCTC12167_00201) - 172184..172924 (-) 741 WP_003098153.1 amino acid ABC transporter ATP-binding protein -
  EL076_RS01030 (NCTC12167_00202) - 172924..174471 (-) 1548 WP_126428933.1 ABC transporter substrate-binding protein/permease -
  EL076_RS01035 (NCTC12167_00203) - 174675..175529 (+) 855 WP_126428935.1 undecaprenyl-diphosphate phosphatase -
  EL076_RS01040 - 175607..175888 (-) 282 WP_126428937.1 DUF3021 family protein -
  EL076_RS01045 (NCTC12167_00204) mecA 176154..176903 (+) 750 WP_126428939.1 adaptor protein MecA Regulator
  EL076_RS01050 (NCTC12167_00205) - 176907..178064 (+) 1158 WP_003098132.1 glycosyltransferase family 4 protein -
  EL076_RS01055 (NCTC12167_00206) sufC 178225..178995 (+) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  EL076_RS01060 (NCTC12167_00207) sufD 179032..180294 (+) 1263 WP_126428941.1 Fe-S cluster assembly protein SufD -
  EL076_RS01065 (NCTC12167_00208) - 180348..181580 (+) 1233 WP_064519082.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29043.63 Da        Isoelectric Point: 4.0182

>NTDB_id=1119863 EL076_RS01045 WP_126428939.1 176154..176903(+) (mecA) [Streptococcus vestibularis strain NCTC12167]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEEIEKALEEVDKTMTEPAKEVAEEAIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGDIYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
SVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=1119863 EL076_RS01045 WP_126428939.1 176154..176903(+) (mecA) [Streptococcus vestibularis strain NCTC12167]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTAATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGATCGTGTGGATGTCTTTGTGACTAAATCAGACCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGATGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAGGGTAACTTTATGGACAAGGGAGATATTGAAGCTCACCATAAGCTCGAAGAGATTGAAAAGGCCTTGGAAGAGGTTG
ATAAGACTATGACAGAGCCGGCTAAGGAAGTGGCTGAGGAAGCTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTAACCTTTACGCAAGGTTTGAAGGATGTGCCAGTGGAAGGTTCTGAACTTTATAAACTTGG
TGATATCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGACTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
TCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

94.378

100

0.944
  mecA Streptococcus thermophilus LMG 18311

93.574

100

0.936
  mecA Streptococcus mutans UA159

59.836

97.992

0.586
  mecA Streptococcus pneumoniae Rx1

46.185

100

0.462
  mecA Streptococcus pneumoniae D39

46.185

100

0.462
  mecA Streptococcus pneumoniae R6

46.185

100

0.462
  mecA Streptococcus pneumoniae TIGR4

46.185

100

0.462

Multiple sequence alignment