Detailed information NTG1119856

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: EL086_RS10400
• Genome accession: NZ_LR134274
• Coordinates: 2203843..2205078 (+)
• Length: 411 a.a.
• NCBI ID: WP_037611167.1
• Uniprot ID: A0AB33ZFB7
• Organism: Streptococcus salivarius strain NCTC8618
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2198843..2210078

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL086_RS10370 (NCTC8618_04521)	-	2199310..2201904 (+)	2595	WP_038676934.1	YfhO family protein	-
EL086_RS10390 (NCTC8618_04525)	-	2202459..2203142 (-)	684	WP_038676936.1	YoaK family protein	-
EL086_RS10395 (NCTC8618_04526)	rlmH	2203158..2203637 (-)	480	WP_022495861.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
EL086_RS10400 (NCTC8618_04527)	htrA	2203843..2205078 (+)	1236	WP_037611167.1	S1C family serine protease	Regulator
EL086_RS10405 (NCTC8618_04528)	spo0J	2205145..2205912 (+)	768	WP_038676938.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42958.12 Da
• Isoelectric Point: 4.6266

>NTDB_id=1119856 EL086_RS10400 WP_037611167.1 2203843..2205078(+) (htrA) [Streptococcus salivarius strain NCTC8618]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNSTDTGVKTAKTVYNNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSNQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDDVKSGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide

• Length: 1236 bp

>NTDB_id=1119856 EL086_RS10400 WP_037611167.1 2203843..2205078(+) (htrA) [Streptococcus salivarius strain NCTC8618]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCGATTGCAATGCTTGTTATTGGCTTACTAGGTGGTTTACTAGGTGC
CTTTATCCTACTAACAGCAGCAGGGGTATCTTTTACCAATTCAACAGATACAGGTGTTAAAACAGCTAAGACCGTATACA
ATAATACAACAGATACAACTAAAGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTACCAAGAAGGGTCA
TCTTCAGATTCTCTAAATGAACTTTATGGCCGTATCTTTGGTGGAGATGATAGTTCTGACTCTAACCAAGACAAATCAAA
AGATTCTGATGGGTTACAAGTCGCTGGTGAAGGTTCCGGTGTTATCTATAAAAAGGATGGTAAAGAGGCTTATATCGTAA
CCAACAACCACGTTGTCGATGGCGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTCGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATTAAAACCGTAGCGGAATTTGCAGACTC
AAACTCTCTCACAGTCGGTGAGAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAGG
GAATCGTTTCTAGCCTTAGCCGTACCGTAACTATGCAAAACGACAATGGTGAAACTGTTTCAACAAATGCTATCCAAACG
GATGCTGCCATTAACCCTGGTAACTCAGGTGGTGCCTTAGTCAATATCGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACATCAGCAGTCGCTGGTAGCGCCGTTGAAGGTATGGGATTTGCCATTCCATCAAACGATGTTGTCGAGA
TTATCAATCAATTGGAAAAAGACGGTAAAGTTACACGACCAGCCCTAGGAATCTCAATGGCCGATCTTAATAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGATGTGAAATCTGGAGTGGTAGTCGGCAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATCACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTGTCTGACTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (307-402)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• Peptidase family M50 (Peptidase_M50) (7-406)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.787	98.054	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.635	98.783	0.569
htrA	Streptococcus pneumoniae Rx1	54.523	99.513	0.543
htrA	Streptococcus pneumoniae R6	54.523	99.513	0.543
htrA	Streptococcus pneumoniae TIGR4	54.523	99.513	0.543
htrA	Streptococcus pneumoniae D39	54.523	99.513	0.543
htrA	Streptococcus mitis NCTC 12261	54.523	99.513	0.543