Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   EL086_RS09685 Genome accession   NZ_LR134274
Coordinates   2068169..2069269 (-) Length   366 a.a.
NCBI ID   WP_126405090.1    Uniprot ID   A0AB37CLB3
Organism   Streptococcus salivarius strain NCTC8618     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2063169..2074269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL086_RS09645 (NCTC8618_04371) - 2063778..2063975 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  EL086_RS09650 (NCTC8618_04372) - 2064226..2065419 (-) 1194 WP_002885831.1 acetate kinase -
  EL086_RS09655 (NCTC8618_04373) comYH 2065476..2066432 (-) 957 WP_038676858.1 class I SAM-dependent methyltransferase Machinery gene
  EL086_RS09660 (NCTC8618_04374) comGG 2066477..2066794 (-) 318 WP_002887013.1 competence type IV pilus minor pilin ComGG -
  EL086_RS09665 (NCTC8618_04375) comYF 2066772..2067209 (-) 438 WP_002887014.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL086_RS09670 (NCTC8618_04376) comGE 2067196..2067426 (-) 231 WP_002887015.1 competence type IV pilus minor pilin ComGE -
  EL086_RS09675 (NCTC8618_04377) comYD 2067458..2067886 (-) 429 WP_254593949.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL086_RS09680 (NCTC8618_04378) comYC 2067846..2068160 (-) 315 WP_170314557.1 competence type IV pilus major pilin ComGC Machinery gene
  EL086_RS09685 (NCTC8618_04379) comYB 2068169..2069269 (-) 1101 WP_126405090.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL086_RS09690 (NCTC8618_04380) comGA/cglA/cilD 2069151..2070092 (-) 942 WP_038676863.1 competence type IV pilus ATPase ComGA Machinery gene
  EL086_RS09695 (NCTC8618_04381) - 2070172..2070534 (-) 363 WP_002887019.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41608.71 Da        Isoelectric Point: 10.1478

>NTDB_id=1119852 EL086_RS09685 WP_126405090.1 2068169..2069269(-) (comYB) [Streptococcus salivarius strain NCTC8618]
MPVKISKAIRQSAGTSSWKAWLNKDISLKGISKGKKLKINQQLKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KTSLMRGDRLDQMFAAVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKENWAVQLVQIFPQLFFATLCGLLVLSLILYLWVKRQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVALMKEQKSKLFRELGADLEEALMLGQSFPDRIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=1119852 EL086_RS09685 WP_126405090.1 2068169..2069269(-) (comYB) [Streptococcus salivarius strain NCTC8618]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAATCAGCTGGAACCAGCAGTTGGAAGGCTTGGTTAAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAACTCAAGGTTATCCAGCTTTTCAAACAACTTTTAA
AGGCAGGGTTTACCTTGACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTAAAAGAATCGTCCTTGTCTCTTATG
AAAACGAGTTTAATGCGAGGCGATAGGTTGGACCAGATGTTTGCGGCAGTGGGCTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAACCTTCTAGGGAGTTTAACCAAGATTGAAACCTATATGCTTCGTATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTACCCTATTCTACTTCTGGGTTTCCTGATTCTGATTATGTTGGGGCTCAAAAAT
TATCTTTTACCTCAACTGTTAGAGGGGGATGGTAAGGAGAATTGGGCTGTACAGTTGGTTCAGATTTTTCCCCAGCTCTT
TTTTGCGACTTTGTGCGGACTTCTTGTATTAAGCTTAATTCTCTACCTATGGGTCAAACGCCAGCCAGCTCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTTATAGGGCAAACTGTCAGGCTATATACGACTGCCTATTATGCTAGGGAATGGGGA
AATCTCTTAGGGCAAGGTATTGACTTGCTAGACTTAGTTGCTCTAATGAAAGAGCAAAAGTCCAAGCTTTTTCGTGAGCT
GGGGGCTGATTTAGAAGAAGCCTTGATGCTAGGACAGAGTTTTCCTGACCGTATTGCTAGTCACCCTTTCTTCACTAAGG
AACTATCCTTAATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.81

93.716

0.514
  comYB Streptococcus mutans UA159

54.81

93.716

0.514
  comYB Streptococcus gordonii str. Challis substr. CH1

51.312

93.716

0.481
  comGB/cglB Streptococcus mitis NCTC 12261

49.558

92.623

0.459
  comGB/cglB Streptococcus mitis SK321

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae Rx1

48.817

92.35

0.451
  comGB/cglB Streptococcus pneumoniae D39

48.817

92.35

0.451
  comGB/cglB Streptococcus pneumoniae R6

48.817

92.35

0.451
  comGB/cglB Streptococcus pneumoniae TIGR4

48.817

92.35

0.451
  comGB Lactococcus lactis subsp. cremoris KW2

44.377

89.891

0.399

Multiple sequence alignment