Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   EL086_RS07470 Genome accession   NZ_LR134274
Coordinates   1639331..1641205 (-) Length   624 a.a.
NCBI ID   WP_038676492.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NCTC8618     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1634331..1646205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL086_RS07435 (NCTC8618_03913) rimM 1634709..1635227 (-) 519 WP_002884411.1 ribosome maturation factor RimM -
  EL086_RS07450 (NCTC8618_03916) - 1635922..1636566 (-) 645 WP_022496266.1 response regulator transcription factor -
  EL086_RS07455 (NCTC8618_03917) - 1636556..1637566 (-) 1011 WP_038676486.1 sensor histidine kinase -
  EL086_RS07460 (NCTC8618_03918) liaF 1637563..1638261 (-) 699 WP_038676488.1 cell wall-active antibiotics response protein LiaF -
  EL086_RS07465 (NCTC8618_03919) - 1638425..1639183 (-) 759 WP_038676489.1 potassium channel family protein -
  EL086_RS07470 (NCTC8618_03920) stkP/pknB 1639331..1641205 (-) 1875 WP_038676492.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EL086_RS07475 (NCTC8618_03921) - 1641205..1641942 (-) 738 WP_038677041.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL086_RS07480 (NCTC8618_03922) rsmB 1641986..1643308 (-) 1323 WP_038677043.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EL086_RS07485 (NCTC8618_03923) fmt 1643298..1644233 (-) 936 WP_038676494.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67870.53 Da        Isoelectric Point: 6.5787

>NTDB_id=1119829 EL086_RS07470 WP_038676492.1 1639331..1641205(-) (stkP/pknB) [Streptococcus salivarius strain NCTC8618]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNERVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSAAQTNIEGAGFKVGEVKEV
EDDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGE
ILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGAKLDKDKVPSSTEV
LYQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=1119829 EL086_RS07470 WP_038676492.1 1639331..1641205(-) (stkP/pknB) [Streptococcus salivarius strain NCTC8618]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAGTCTATCGGGCGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGAGTAGCTATTAAGGTGCTACGTACCAATTACCAAACGGATCAGGTGG
CTGTGGCGCGTTTCCAGCGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTTTTGGTGATGGAGTATGTGGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTTCTTTCCGCCATGACTCTTGCCCACCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTCACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACTAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
GAAAGCAACTATCCAAAGCGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GTGACAGTGCAGTAACCATTGCACTCCAACATTTCCAAAAGCCACTCCCATCTATTTTGGCAGAGAACCGTAATGTTCCC
CAAGCCTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAACTAGAGAATCGTTATAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCCAAGGTAGTCTTTGATGATATGACGGATACCAAGACCT
TGCCAAAGGTTGATCCAGTTCCATCTGCAAGTCTTGAGAAAAAAGCCGTTGCTGCTGAGCCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCAAGGAAAAAAACGACACCAGCTAAGAAGAAAAAGAAGAAAAACTTTTTCTCAACCTTGCTCAAGGT
TTTCCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCCTATTTGGTATTTACCAATCCTGATAATGTCCAGGTGCCTA
ATGTGGTCGGTCAAGAGTTGTCCGCAGCTCAGACTAACATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTTAAGGAAGTG
GAAGATGACTCTGTCGATACAGGAAAGGTCATCAAGACTGATCCTACAGCTGGAACCACACGAAAAGAGGGATCAAGCAT
TGATGTCTATGTTTCTTCTGGTAGTAAAGGTTTTGCGTTGAAAGACTACAAAGGTAAAAACTACAAAGATGCCATTGAGG
ACTTAACTTCGAATTATGGCGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAA
ATCCTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCCAAGATTAAGTTCCGTGTGGCAAC
TCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGAGTATCT
CAAGTAGTAGTATCGAGTATCATGACTATAATACTGGTGCCAAGTTAGACAAGGATAAGGTTCCTAGCAGTACAGAGGTC
CTTTATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCAGTTGCAACAGCAAGTTCAAG
TCTACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAA
CCTCGACAGAGGCTACTCACACAGAGCTACAGTAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(370-432)

PASTA domain (PASTA)

(511-580)

Protein kinase domain (Pkinase)

(12-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.558

100

0.986
  pknB Streptococcus mutans UA159

66.974

86.859

0.582
  stkP Streptococcus pneumoniae TIGR4

52.324

93.109

0.487
  stkP Streptococcus pneumoniae D39

52.151

93.109

0.486
  stkP Streptococcus pneumoniae R6

52.151

93.109

0.486
  stkP Streptococcus pneumoniae Rx1

51.979

93.109

0.484

Multiple sequence alignment