Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   EL081_RS02575 Genome accession   NZ_LR134266
Coordinates   472906..474777 (+) Length   623 a.a.
NCBI ID   WP_126403854.1    Uniprot ID   -
Organism   Streptococcus viridans strain NCTC3166     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 467906..479777
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL081_RS02560 (NCTC3166_00515) fmt 469909..470844 (+) 936 WP_126403852.1 methionyl-tRNA formyltransferase -
  EL081_RS02565 (NCTC3166_00516) rsmB 470834..472147 (+) 1314 WP_126403853.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EL081_RS02570 (NCTC3166_00517) - 472169..472909 (+) 741 WP_048691932.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL081_RS02575 (NCTC3166_00518) stkP 472906..474777 (+) 1872 WP_126403854.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EL081_RS02580 (NCTC3166_00519) liaF 474908..475603 (+) 696 WP_126403855.1 cell wall-active antibiotics response protein LiaF -
  EL081_RS02585 (NCTC3166_00520) - 475600..476619 (+) 1020 WP_126403856.1 sensor histidine kinase -
  EL081_RS02590 (NCTC3166_00521) - 476597..477229 (+) 633 WP_126403857.1 response regulator transcription factor -
  EL081_RS02595 (NCTC3166_00522) - 477273..478679 (+) 1407 WP_126403858.1 Cof-type HAD-IIB family hydrolase -
  EL081_RS02600 (NCTC3166_00523) - 478676..479044 (+) 369 WP_126403859.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 68494.57 Da        Isoelectric Point: 5.2801

>NTDB_id=1119562 EL081_RS02575 WP_126403854.1 472906..474777(+) (stkP) [Streptococcus viridans strain NCTC3166]
MIQIGKIFAGRYKIIRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMADLDHPNIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKENAPLSNEEAVRLMGQILLAMRLAHTQGIIHRDLKPQNVLLTSDGNAKVSDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKASVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIEENKNVP
QALENVVIKATAKKLSDRYKSVAEMYVDLSSCLSYERRNEKKLVFDDASKADTKTLPKVNVVPKPAPLPTSDVRPAVHED
LPGTSEDRTVPVSPKNKPRRRLRTRYKVLFVALALVLAAFAFLLYMSPANKTVPDVSGKTVAEARAIIEDQDLQVGDEKE
EYSDSVLEGYVIRTNPNAGAQKKENSKVDLVVSKGPSTFEMPDYTGMSREDAENDLKTTYKLSSKLISIEEVETNEVEPG
IVMEQSPAAGQKYDLTSNTKVVLKVSKESNSIELPSYVGSYYEFAVSNLVQIYGVKEANIERKTTSHLPDGVEVLPGQIV
SQTPEAQSSIDIKKTRIVLTVYEPKTEPSSSTKASSSSSESSSSTTVESHSNTEPSASTEPES

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=1119562 EL081_RS02575 WP_126403854.1 472906..474777(+) (stkP) [Streptococcus viridans strain NCTC3166]
ATGATTCAAATCGGCAAAATTTTTGCCGGACGATATAAGATAATCCGCCAAATCGGGCGTGGAGGAATGGCAGATGTCTA
CCTCGCTCGGGATTTAATCTTAGATGGTGAAGAAGTTGCAGTTAAAGTACTGAGGACCAATTACCAAACAGATCCAATTG
CAGTTGCTCGCTTCCAACGAGAGGCCAAAGCGATGGCAGATTTGGATCATCCAAATATCGTTCGGATCACGGATATCGGT
GAAGAAGATGGCCAACAATACTTGGCGATGGAATATGTCGCTGGTTTGGACTTGAAACGCTATATCAAAGAAAATGCTCC
TCTCTCAAATGAAGAAGCTGTTCGCTTGATGGGGCAAATCCTTCTTGCTATGCGTTTGGCGCACACGCAAGGCATTATTC
ACCGTGATTTGAAACCTCAAAATGTCCTTTTAACATCGGACGGAAATGCCAAGGTTTCTGACTTTGGGATTGCGGTAGCA
TTTGCAGAAACAAGCCTCACTCAGACCAACTCCATGTTGGGATCGGTTCATTATTTGTCACCTGAACAAGCCAGAGGATC
GAAAGCTTCTGTTCAAAGTGACATCTATGCGATGGGGATCATTTTCTATGAAATGCTGACGGGACATATCCCTTATGATG
GGGATAGTGCAGTGACCATCGCGTTGCAACATTTCCAAAAACCACTGCCGTCCATCATCGAAGAGAACAAAAATGTTCCG
CAGGCCTTGGAAAATGTGGTGATTAAGGCAACGGCAAAGAAACTATCCGATCGCTATAAGTCGGTAGCTGAAATGTATGT
CGACTTGTCTAGTTGCCTATCTTATGAACGCCGTAACGAGAAAAAATTAGTCTTTGATGACGCTTCAAAAGCGGATACCA
AGACCCTACCAAAGGTAAACGTGGTTCCAAAACCAGCTCCACTTCCAACATCAGATGTTCGTCCGGCTGTTCATGAGGAC
CTACCAGGGACTTCAGAGGATAGAACAGTTCCAGTTTCTCCAAAAAATAAGCCACGTCGTCGTTTGAGGACACGCTATAA
AGTCTTGTTTGTTGCTTTAGCTTTGGTACTAGCTGCCTTTGCCTTTCTTCTTTATATGAGTCCAGCCAACAAAACAGTTC
CGGATGTATCTGGAAAAACTGTCGCAGAAGCTCGGGCTATCATTGAAGATCAGGATCTTCAAGTTGGAGACGAAAAAGAA
GAATACAGTGATTCTGTACTTGAGGGCTATGTCATTCGAACCAATCCAAATGCTGGAGCTCAGAAAAAGGAAAACAGCAA
GGTTGATTTGGTTGTCTCGAAAGGGCCAAGCACCTTTGAAATGCCGGACTATACTGGTATGTCTAGAGAAGATGCGGAAA
ACGACCTAAAAACCACCTATAAGCTTTCTAGCAAGCTCATTTCGATTGAAGAAGTCGAGACCAATGAAGTGGAACCAGGA
ATCGTTATGGAGCAATCTCCTGCTGCTGGTCAAAAATATGATTTGACTTCTAATACGAAAGTTGTTCTGAAAGTATCTAA
GGAGAGTAATTCTATCGAGTTACCAAGTTATGTCGGTTCATATTATGAATTTGCTGTCTCTAATCTCGTTCAGATCTACG
GGGTGAAGGAAGCAAATATTGAACGGAAGACCACATCGCATCTTCCGGATGGTGTAGAAGTCCTACCAGGTCAAATTGTG
AGTCAGACTCCAGAAGCTCAATCGAGCATCGATATTAAAAAGACTCGCATTGTCTTGACTGTATACGAACCGAAGACGGA
ACCATCAAGTAGCACGAAAGCTTCAAGCAGTTCATCAGAAAGTTCAAGCTCGACAACAGTGGAATCCCATTCCAATACGG
AACCTTCGGCTTCTACTGAACCAGAATCTTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-255)

PASTA domain (PASTA)

(513-582)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(440-507)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

63.203

94.222

0.596
  stkP Streptococcus pneumoniae D39

63.032

94.222

0.594
  stkP Streptococcus pneumoniae R6

63.032

94.222

0.594
  stkP Streptococcus pneumoniae Rx1

62.862

94.222

0.592
  pknB Streptococcus mutans UA159

58.118

86.998

0.506
  stkP/pknB Streptococcus salivarius strain HSISS4

52.872

95.024

0.502

Multiple sequence alignment