Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EL071_RS04540 Genome accession   NZ_LR134265
Coordinates   837922..838677 (+) Length   251 a.a.
NCBI ID   WP_115357040.1    Uniprot ID   A0AB38VL76
Organism   Streptococcus agalactiae strain NCTC8184     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 832922..843677
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL071_RS04525 (NCTC8184_00881) - 833348..834898 (-) 1551 WP_000722379.1 ABC transporter substrate-binding protein/permease -
  EL071_RS04530 (NCTC8184_00882) - 835034..836917 (+) 1884 WP_115357057.1 DUF2207 domain-containing protein -
  EL071_RS04535 (NCTC8184_00883) - 836963..837802 (+) 840 WP_000905327.1 undecaprenyl-diphosphate phosphatase -
  EL071_RS04540 (NCTC8184_00884) mecA 837922..838677 (+) 756 WP_115357040.1 adaptor protein MecA Regulator
  EL071_RS04545 (NCTC8184_00885) - 838679..839839 (+) 1161 WP_000612109.1 MraY family glycosyltransferase -
  EL071_RS04550 (NCTC8184_00886) sufC 840004..840774 (+) 771 WP_000114502.1 Fe-S cluster assembly ATPase SufC -
  EL071_RS04555 (NCTC8184_00887) sufD 840811..842073 (+) 1263 WP_000031277.1 Fe-S cluster assembly protein SufD -
  EL071_RS04560 (NCTC8184_00888) - 842075..843307 (+) 1233 WP_000173347.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29070.95 Da        Isoelectric Point: 4.2155

>NTDB_id=1119503 EL071_RS04540 WP_115357040.1 837922..838677(+) (mecA) [Streptococcus agalactiae strain NCTC8184]
MEMKQISETTLKITISMEDLEDRGMELKDFLIPQEKTEEFFYSVMDELDLPENFKNSGMLSFRVTPKKDRIDVFVTKSEL
SKDLNLEELADLGDISKMSPEDFFKTLEQSMLEKGDTDAHAKLAEIENMMDKATQEVVEENVSEEQPEKEVETIGYVHYV
FDFDNIEAVVRFSQTIDFPIEASELYKNGKGYHMTILLDLENQLSYFANLMYARMLEHANVGTKTRAYLKEHSIQLIHDD
AISKLQMIEMG

Nucleotide


Download         Length: 756 bp        

>NTDB_id=1119503 EL071_RS04540 WP_115357040.1 837922..838677(+) (mecA) [Streptococcus agalactiae strain NCTC8184]
ATGGAAATGAAACAAATCAGTGAAACAACACTGAAAATTACAATTAGTATGGAAGATTTAGAAGATCGTGGTATGGAGCT
GAAAGATTTCCTAATCCCTCAGGAGAAGACTGAGGAATTTTTCTATTCTGTCATGGATGAATTAGACTTGCCAGAAAACT
TTAAAAATAGTGGTATGTTAAGTTTTCGAGTAACACCTAAAAAAGATCGCATTGATGTTTTTGTTACAAAGTCTGAATTA
AGTAAAGATTTAAATTTAGAAGAATTAGCAGATTTGGGTGACATTTCAAAAATGTCTCCAGAAGACTTTTTTAAAACCTT
GGAACAATCGATGTTGGAAAAAGGGGATACGGATGCCCATGCCAAATTAGCAGAAATTGAAAATATGATGGATAAAGCAA
CTCAAGAAGTAGTTGAGGAAAATGTTTCTGAAGAACAACCTGAAAAGGAAGTAGAAACGATTGGATATGTTCACTATGTC
TTTGATTTTGATAATATTGAAGCTGTAGTTCGATTTTCACAAACGATTGATTTTCCAATAGAAGCTTCTGAACTCTATAA
AAATGGTAAAGGCTATCATATGACAATTTTGCTAGACTTGGAAAACCAACTAAGCTACTTTGCTAATTTGATGTATGCTC
GAATGCTTGAACATGCTAATGTGGGCACAAAAACACGAGCTTACTTGAAAGAGCATAGTATTCAATTGATTCATGATGAT
GCTATTTCAAAATTACAAATGATTGAGATGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

67.339

98.805

0.665
  mecA Streptococcus thermophilus LMD-9

59.761

100

0.598
  mecA Streptococcus thermophilus LMG 18311

58.964

100

0.59
  mecA Streptococcus pneumoniae Rx1

46.215

100

0.462
  mecA Streptococcus pneumoniae D39

46.215

100

0.462
  mecA Streptococcus pneumoniae R6

46.215

100

0.462
  mecA Streptococcus pneumoniae TIGR4

46.215

100

0.462

Multiple sequence alignment