Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   EL020_RS06145 Genome accession   NZ_LR134203
Coordinates   1192078..1192752 (-) Length   224 a.a.
NCBI ID   WP_020916820.1    Uniprot ID   A0AB33ALR7
Organism   Streptococcus lutetiensis strain NCTC11436     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1187078..1197752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL020_RS06120 (NCTC11436_01278) - 1187262..1187855 (-) 594 WP_020916816.1 class I SAM-dependent methyltransferase -
  EL020_RS06125 (NCTC11436_01279) coaA 1187987..1188907 (+) 921 WP_020916817.1 type I pantothenate kinase -
  EL020_RS06130 (NCTC11436_01280) rpsT 1188983..1189234 (+) 252 WP_004231769.1 30S ribosomal protein S20 -
  EL020_RS06135 - 1189366..1190717 (+) 1352 WP_126402565.1 IS3 family transposase -
  EL020_RS06140 (NCTC11436_01283) ciaH 1190760..1192088 (-) 1329 WP_020916819.1 sensor histidine kinase Regulator
  EL020_RS06145 (NCTC11436_01284) ciaR 1192078..1192752 (-) 675 WP_020916820.1 response regulator transcription factor Regulator
  EL020_RS06150 (NCTC11436_01285) - 1192920..1195463 (-) 2544 WP_126402566.1 M1 family metallopeptidase -
  EL020_RS06155 (NCTC11436_01286) phoU 1195694..1196347 (-) 654 WP_020916822.1 phosphate signaling complex protein PhoU -
  EL020_RS06160 (NCTC11436_01287) pstB 1196378..1197136 (-) 759 WP_020916823.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25402.03 Da        Isoelectric Point: 4.3421

>NTDB_id=1118969 EL020_RS06145 WP_020916820.1 1192078..1192752(-) (ciaR) [Streptococcus lutetiensis strain NCTC11436]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKGGFQVLKELREQGITTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNDNTLSYHELTADTSTNTTTVNGEKVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTSFAKNLQTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1118969 EL020_RS06145 WP_020916820.1 1192078..1192752(-) (ciaR) [Streptococcus lutetiensis strain NCTC11436]
ATGATTAAGATTTTATTAGTAGAAGATGATTTGAGTTTATCGAATTCAATCTTTGATTTTTTAGACGATTTTGCGGATGT
TATGCAAGTCTTTGATGGTGAAGAAGGACTTTATGAGGCAGAAAGTGGTGTTTATGACCTTATTTTGCTTGATCTGATGT
TGCCAGAAAAAGGTGGTTTCCAAGTTCTGAAAGAATTACGTGAACAAGGTATTACGACACCTGTCTTAATTATGACTGCA
AAAGAAAGCCTTGATGATAAAGGACATGGCTTTGAACTTGGTGCAGATGACTATTTGACAAAACCATTTTATCTTGAAGA
ATTAAAGATGCGCATTCAAGCGCTTTTGAAACGCTCTGGAAAATTCAACGATAATACTCTTTCTTACCACGAATTAACAG
CCGATACATCAACTAACACAACAACTGTTAACGGTGAAAAGGTTGAGTTACTAGGTAAAGAATTTGATTTACTGGTTTAT
TTCTTGCAAAACCAAAATGTTATTTTGCCAAAATCACAAATTTTTGACCGTATTTGGGGATTTGATAGCGATACTACAAT
TTCAGTTGTTGAAGTTTATGTTTCTAAGATTCGCAAAAAATTAAAAGGAACAAGTTTTGCTAAAAATCTACAAACACTTC
GTAGTGTAGGATATATTCTAAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

92.825

99.554

0.924
  ciaR Streptococcus pneumoniae Rx1

87.946

100

0.879
  ciaR Streptococcus pneumoniae D39

87.946

100

0.879
  ciaR Streptococcus pneumoniae R6

87.946

100

0.879
  ciaR Streptococcus pneumoniae TIGR4

87.946

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.885

100

0.384
  vicR Streptococcus mutans UA159

34.764

100

0.362

Multiple sequence alignment