Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ELZ63_RS02025 Genome accession   NZ_LR134171
Coordinates   396329..397549 (+) Length   406 a.a.
NCBI ID   WP_065244996.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC12699     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 391329..402549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ63_RS02005 (NCTC12699_00401) corC 392289..393188 (-) 900 WP_065245000.1 CNNM family magnesium/cobalt transport protein CorC -
  ELZ63_RS02010 (NCTC12699_00402) ampD 393820..394374 (-) 555 WP_065244999.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  ELZ63_RS02015 (NCTC12699_00403) pilA 394489..394938 (+) 450 WP_065244998.1 prepilin peptidase-dependent pilin Machinery gene
  ELZ63_RS02020 (NCTC12699_00404) pilB 394935..396332 (+) 1398 WP_065244997.1 GspE/PulE family protein Machinery gene
  ELZ63_RS02025 (NCTC12699_00405) pilC 396329..397549 (+) 1221 WP_065244996.1 type II secretion system F family protein Machinery gene
  ELZ63_RS02030 (NCTC12699_00406) pilD 397546..398238 (+) 693 WP_065244995.1 A24 family peptidase Machinery gene
  ELZ63_RS02035 (NCTC12699_00407) rho 398291..399553 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  ELZ63_RS02040 (NCTC12699_00408) metJ 399801..400118 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  ELZ63_RS02045 (NCTC12699_00409) cueR 400132..400518 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  ELZ63_RS02050 (NCTC12699_00410) - 400595..400801 (+) 207 WP_065244994.1 heavy-metal-associated domain-containing protein -
  ELZ63_RS02055 (NCTC12699_00411) - 400876..401082 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  ELZ63_RS02060 (NCTC12699_00412) - 401156..401362 (+) 207 WP_005648955.1 heavy-metal-associated domain-containing protein -
  ELZ63_RS02065 (NCTC12699_00413) - 401448..401654 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  ELZ63_RS02070 (NCTC12699_00414) - 401740..401946 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46319.53 Da        Isoelectric Point: 9.7232

>NTDB_id=1118736 ELZ63_RS02025 WP_065244996.1 396329..397549(+) (pilC) [Haemophilus influenzae strain NCTC12699]
MTKKLFYYQASNALNQEQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDMVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIVDNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=1118736 ELZ63_RS02025 WP_065244996.1 396329..397549(+) (pilC) [Haemophilus influenzae strain NCTC12699]
ATGACTAAAAAACTCTTTTATTATCAAGCTAGTAACGCATTAAATCAGGAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGTGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCTATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTTACTCAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTTCCGTTGTTTGTAAAAAAATAGCCACGCATCGTAGCCAATCTTTAGCATTGCAACGTAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCTGAGTTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTGAGTTTTTTTCTATTTTATTATTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCCGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAACGATATGGTATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGTGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTACTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

98.276

100

0.983
  pilC Haemophilus influenzae Rd KW20

98.03

100

0.98
  pilC Glaesserella parasuis strain SC1401

37.905

98.768

0.374

Multiple sequence alignment