Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ELZ51_RS01800 Genome accession   NZ_LR134094
Coordinates   327002..327763 (+) Length   253 a.a.
NCBI ID   WP_115246692.1    Uniprot ID   A0A380JY53
Organism   Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 322002..332763
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ51_RS01785 (NCTC4669_00380) - 322261..323829 (-) 1569 WP_115246695.1 ABC transporter substrate-binding protein/permease -
  ELZ51_RS01790 (NCTC4669_00381) - 324028..325953 (+) 1926 WP_126425825.1 DUF2207 domain-containing protein -
  ELZ51_RS01795 (NCTC4669_00382) - 326019..326858 (+) 840 WP_126425827.1 undecaprenyl-diphosphate phosphatase -
  ELZ51_RS01800 (NCTC4669_00383) mecA 327002..327763 (+) 762 WP_115246692.1 adaptor protein MecA Regulator
  ELZ51_RS01805 (NCTC4669_00384) - 327770..328939 (+) 1170 WP_115246691.1 glycosyltransferase family 4 protein -
  ELZ51_RS01810 (NCTC4669_00385) sufC 329052..329822 (+) 771 WP_126425829.1 Fe-S cluster assembly ATPase SufC -
  ELZ51_RS01815 (NCTC4669_00386) sufD 329919..331181 (+) 1263 WP_115252602.1 Fe-S cluster assembly protein SufD -
  ELZ51_RS01820 (NCTC4669_00387) - 331212..332438 (+) 1227 WP_126425831.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29183.85 Da        Isoelectric Point: 4.0916

>NTDB_id=1118260 ELZ51_RS01800 WP_115246692.1 327002..327763(+) (mecA) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKDLNLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEDVVEATLVSQTEETAEEVEQEPEPLDYVH
YVLDFATLSEAVAFSRTIDFPVEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEHASPGTKTRAYLQEHGVQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=1118260 ELZ51_RS01800 WP_115246692.1 327002..327763(+) (mecA) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGGAAATGAAACAAATTAGTGAGACAACGCTAAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGGATGGAATT
AAAAGATTTTCTCATTCCTCAAGAAAAAACGGAAGAGTTCTTCTACTCTGTCATGGATGAGTTGGATCTACCAGACAATT
TCAAAGATAGTGGCATGCTTAGCTTTCGTGTGACCCCTAGAAAAGACCGTTTGGATGTCTTTGTAACCAAGTCTGAACTC
AATAAGGACCTTAATCTTGAGGATTTAGCTGATTTGGGAGACATCTCTCAAATGACTCCTGAAGACTTTTTCAAGAGCTT
AGAACAATCTATGCGAGAAAAAGGGGATGTAAATGCCCATGAGAAACTGGAAAAAATTGAAGAAATGATGGAAGACGTTG
TTGAAGCAACTCTAGTTAGTCAAACGGAAGAGACCGCTGAGGAAGTGGAACAAGAACCAGAGCCGTTAGATTACGTGCAT
TATGTTTTGGACTTTGCAACACTTTCAGAGGCCGTCGCTTTTTCTCGGACAATTGATTTTCCTGTTGAAGCTTCAGAATT
GTATAAAGGTGACAGCCGTTATCATATGACGATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCCAATGTGATGT
ATGCAAGACTGATTGAGCATGCTAGTCCTGGAACAAAAACAAGAGCTTACTTACAAGAGCATGGCGTACAATTAATTCTG
GATGGAGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380JY53

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.4

98.814

0.636
  mecA Streptococcus thermophilus LMD-9

57.028

98.419

0.561
  mecA Streptococcus thermophilus LMG 18311

56.225

98.419

0.553
  mecA Streptococcus pneumoniae Rx1

47.843

100

0.482
  mecA Streptococcus pneumoniae D39

47.843

100

0.482
  mecA Streptococcus pneumoniae R6

47.843

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.843

100

0.482

Multiple sequence alignment