Detailed information NTG1118250

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: ELZ51_RS00370
• Genome accession: NZ_LR134094
• Coordinates: 57195..58106 (+)
• Length: 303 a.a.
• NCBI ID: WP_126425593.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 52195..63106

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ51_RS00350 (NCTC4669_00071)	purD	52674..53936 (+)	1263	WP_126425587.1	phosphoribosylamine--glycine ligase	-
ELZ51_RS00355 (NCTC4669_00072)	purE	54191..54679 (+)	489	WP_003049074.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
ELZ51_RS00360 (NCTC4669_00073)	purK	54666..55751 (+)	1086	WP_126425589.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
ELZ51_RS00365 (NCTC4669_00074)	purB	55761..57053 (+)	1293	WP_126425591.1	adenylosuccinate lyase	-
ELZ51_RS00370 (NCTC4669_00075)	comR	57195..58106 (+)	912	WP_126425593.1	helix-turn-helix domain-containing protein	Regulator
ELZ51_RS11195 (NCTC4669_00076)	comS	58193..58288 (+)	96	WP_198455558.1	quorum-sensing system DWW-type pheromone	Regulator
ELZ51_RS00375 (NCTC4669_00077)	ruvB	58339..59337 (+)	999	WP_003049085.1	Holliday junction branch migration DNA helicase RuvB	-
ELZ51_RS00380 (NCTC4669_00078)	-	59472..59903 (+)	432	WP_003049087.1	low molecular weight protein-tyrosine-phosphatase	-
ELZ51_RS00385 (NCTC4669_00079)	-	59932..60333 (+)	402	WP_003049089.1	MORN repeat-containing protein	-
ELZ51_RS00390 (NCTC4669_00080)	-	60330..62105 (+)	1776	WP_003049091.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35657.25 Da
• Isoelectric Point: 4.5798

>NTDB_id=1118250 ELZ51_RS00370 WP_126425593.1 57195..58106(+) (comR) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDGKLQVRESQFDEIFENYYDQLPEEEKLIIECLQATLDTLLSENINFGVELLQEYFKQTKVKLRFKQND
LILIELYLAYLDIEGMYGEYSDKVFYDSLLDNLLKQFDDFELDELFIVNKIIIDISSLSIKTNKLDNLEKTIAISQKIMT
KIQDWNRMPILKLIEWKYFLIKQKNRKQAEESYTKACLFAQITGDKYLEEQLIKEWEKDICAY

Nucleotide

• Length: 912 bp

>NTDB_id=1118250 ELZ51_RS00370 WP_126425593.1 57195..58106(+) (comR) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGACTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTATGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCAAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAATCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATGGGAAATTGCAAGTCCGAGAGTCTCAGTTTGATGAGATATTCGA
AAACTATTATGATCAATTGCCCGAGGAGGAAAAATTGATTATAGAATGTTTACAGGCTACGCTAGACACTTTATTGAGTG
AAAACATCAATTTTGGTGTTGAATTATTGCAGGAATATTTTAAACAAACCAAAGTTAAGCTACGTTTTAAACAAAACGAC
TTGATACTTATTGAACTCTATCTGGCTTATCTCGATATTGAAGGGATGTATGGAGAATATTCTGATAAGGTTTTTTATGA
TTCTTTGTTAGATAACCTGTTAAAACAATTCGATGACTTTGAATTAGACGAACTGTTCATAGTTAATAAAATTATTATTG
ATATTTCTTCTTTAAGTATTAAAACTAATAAACTAGATAATCTAGAAAAGACGATTGCTATAAGTCAAAAAATCATGACA
AAAATTCAGGATTGGAATAGAATGCCTATACTAAAATTAATAGAATGGAAGTACTTTTTAATAAAGCAAAAGAACAGAAA
ACAAGCAGAGGAATCATATACAAAGGCGTGTCTGTTTGCGCAGATAACAGGAGACAAGTATTTGGAAGAGCAATTAATTA
AAGAATGGGAGAAAGATATTTGTGCTTATTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	82.508	100	0.825
comR	Streptococcus pyogenes MGAS315	55.333	99.01	0.548
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.186	97.36	0.498
comR	Streptococcus mutans UA159	49.164	98.68	0.485