Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   ELZ47_RS02635 Genome accession   NZ_LR134002
Coordinates   525589..527439 (+) Length   616 a.a.
NCBI ID   WP_126435198.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC 10904     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 520589..532439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ47_RS02620 (NCTC10904_00518) fmt 522592..523527 (+) 936 WP_126435194.1 methionyl-tRNA formyltransferase -
  ELZ47_RS02625 (NCTC10904_00519) rsmB 523517..524833 (+) 1317 WP_126435196.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ELZ47_RS02630 (NCTC10904_00520) - 524852..525592 (+) 741 WP_002893499.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ELZ47_RS02635 (NCTC10904_00521) stkP 525589..527439 (+) 1851 WP_126435198.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ELZ47_RS02640 (NCTC10904_00522) liaF 527582..528277 (+) 696 WP_002893496.1 cell wall-active antibiotics response protein LiaF -
  ELZ47_RS02645 (NCTC10904_00523) - 528274..529293 (+) 1020 WP_126435200.1 sensor histidine kinase -
  ELZ47_RS02650 (NCTC10904_00524) - 529271..529903 (+) 633 WP_009659067.1 response regulator transcription factor -
  ELZ47_RS02655 (NCTC10904_00525) - 529943..531343 (+) 1401 WP_125331610.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ELZ47_RS02660 (NCTC10904_00526) - 531343..531705 (+) 363 WP_002901252.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 616 a.a.        Molecular weight: 67657.62 Da        Isoelectric Point: 6.3744

>NTDB_id=1117806 ELZ47_RS02635 WP_126435198.1 525589..527439(+) (stkP) [Streptococcus sanguinis strain NCTC 10904]
MIQIGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKENSPISNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNVLLTPDGNAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIISENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSSLSYERRNEKKLVFDDVAKADTKTLPKISPVPQPAVPPVKSTPPKAEAT
EVKEETADAVKKVPKKRRLRTRYKVLFFAVLLVLAAFVVLLYNSPSNTSVPDVSGQTVAEARSAIEAKKLVVGDEKEEYS
DNVESGKVIKTDPQANSQRREGSKIDLIISKGPKTFVMEDYTERLKDAAVKDLKENFKVPEKLIEIVEEESDEYEPGQVI
RQSPAAGSTYDLTSNHKIKLTVAKEVTSVSMPDFGSMQYTYANARSYLIQMGISSSRIERVVDRSVTSTQADLVTSQSPA
AGQTIDLKSNEKITLYVTEATTPSSSSSSSSSSNSKSSSSSDDESHSSSSSSSEHQ

Nucleotide


Download         Length: 1851 bp        

>NTDB_id=1117806 ELZ47_RS02635 WP_126435198.1 525589..527439(+) (stkP) [Streptococcus sanguinis strain NCTC 10904]
ATGATTCAAATCGGCAAAATCTTTGCCGGGCGATATAAAATCATCAAGCAGATTGGCCGCGGAGGCATGGCAGATGTCTA
TCTGGCCAAGGACTTGATTTTGGATGGTGAGGAAGTTGCGGTAAAGGTTCTTAGAACCAATTACCAGACAGATCCTATCG
CTGTCGCGCGTTTCCAGCGGGAAGCTAAGGCGATGGCTGATTTGGACCATCCGCACATCGTTCGGATCACTGATATTGGG
GAAGAAGACGGCCAGCAGTATCTGGCTATGGAATACGTAGCAGGTCTTGACCTCAAGCGCTATATCAAAGAGAATTCTCC
GATTTCAAATGAAGAAGCAGTCAGAATCATGGGACAAATCTTGCTGGCGATGCGCTTAGCGCATACACGCGGTATTGTCC
ATCGTGACCTGAAACCACAAAATGTCCTCTTAACCCCGGATGGCAATGCCAAGGTAACAGACTTTGGGATTGCGGTGGCC
TTTGCAGAGACAAGTCTGACTCAGACCAACTCTATGCTGGGCTCGGTTCATTATCTATCGCCTGAGCAGGCGCGTGGCTC
TAAAGCAACTGTTCAGAGTGATATTTATGCAATGGGGATTATTTTTTATGAGATGCTGACAGGTCATATCCCTTATGACG
GGGATAGTGCCGTTACGATTGCTCTTCAGCATTTCCAAAAGCCGCTGCCATCCATCATTTCTGAAAATCCTAATGTGCCT
CAAGCCTTGGAAAATGTGGTCATTAAGGCAACAGCCAAAAAACTGACGGATCGCTATCAGTCGGTTGCAGAGATGTATGT
TGACTTGTCTAGCAGCTTATCTTATGAGCGCCGCAATGAAAAGAAATTGGTCTTTGATGATGTAGCGAAAGCAGACACCA
AGACCTTGCCAAAAATCTCGCCTGTACCGCAGCCAGCAGTTCCACCTGTTAAGTCAACACCGCCTAAAGCGGAAGCGACT
GAAGTTAAGGAAGAGACAGCTGATGCGGTTAAGAAAGTTCCAAAGAAACGTCGTTTGAGAACGCGTTACAAGGTACTTTT
CTTTGCAGTCCTATTGGTTTTGGCGGCTTTTGTTGTCCTTCTTTATAATAGCCCATCCAATACCAGCGTGCCAGATGTTT
CTGGTCAGACTGTAGCAGAGGCTCGTTCCGCTATCGAAGCTAAGAAGCTGGTTGTCGGAGACGAAAAGGAAGAATACAGC
GACAATGTCGAATCTGGCAAAGTCATTAAAACTGATCCACAGGCCAATAGTCAGCGCCGCGAAGGCAGCAAGATTGACCT
GATTATCTCCAAGGGGCCCAAGACCTTTGTGATGGAAGATTATACTGAGAGACTGAAAGATGCGGCCGTCAAAGATTTGA
AAGAAAACTTTAAGGTTCCTGAGAAATTGATTGAGATTGTTGAGGAGGAATCGGACGAGTACGAGCCAGGTCAGGTGATT
CGTCAGTCACCGGCAGCTGGTTCGACCTATGATTTGACTTCTAATCATAAGATCAAGCTGACAGTAGCCAAAGAAGTAAC
TAGTGTATCCATGCCTGACTTTGGCAGCATGCAGTACACCTACGCCAATGCACGTTCTTACTTGATCCAAATGGGAATTT
CTTCTTCCCGAATTGAGCGAGTTGTTGACCGTTCGGTCACTTCTACTCAGGCAGACTTGGTAACTTCCCAGTCACCAGCA
GCAGGTCAGACTATTGACCTCAAATCTAATGAAAAAATCACTCTTTACGTGACAGAAGCAACGACACCATCATCATCTAG
TTCGTCATCATCATCTAGCAACTCGAAGAGCAGTTCATCGTCCGATGATGAAAGTCATTCTAGTAGCTCTAGTTCTTCAG
AACATCAATGA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-232)

PASTA domain (PASTA)

(510-578)

PASTA domain (PASTA)

(437-504)

PASTA domain (PASTA)

(370-431)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

63.819

96.916

0.619
  stkP Streptococcus pneumoniae D39

63.484

96.916

0.615
  stkP Streptococcus pneumoniae R6

63.484

96.916

0.615
  stkP Streptococcus pneumoniae Rx1

63.317

96.916

0.614
  pknB Streptococcus mutans UA159

57.922

95.292

0.552
  stkP/pknB Streptococcus salivarius strain HSISS4

55.593

97.24

0.541

Multiple sequence alignment