Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ELZ47_RS02060 Genome accession   NZ_LR134002
Coordinates   408356..409108 (+) Length   250 a.a.
NCBI ID   WP_125445632.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC 10904     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 403356..414108
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ47_RS02045 (NCTC10904_00406) - 403606..405171 (-) 1566 WP_126435135.1 ABC transporter substrate-binding protein/permease -
  ELZ47_RS02050 (NCTC10904_00407) - 405303..407198 (+) 1896 WP_126435137.1 DUF2207 domain-containing protein -
  ELZ47_RS02055 (NCTC10904_00408) - 407338..408180 (+) 843 WP_126435138.1 undecaprenyl-diphosphate phosphatase -
  ELZ47_RS02060 (NCTC10904_00409) mecA 408356..409108 (+) 753 WP_125445632.1 adaptor protein MecA Regulator
  ELZ47_RS02065 (NCTC10904_00410) - 409099..410265 (+) 1167 WP_126435140.1 glycosyltransferase family 4 protein -
  ELZ47_RS02070 (NCTC10904_00411) sufC 410355..411125 (+) 771 WP_126435142.1 Fe-S cluster assembly ATPase SufC -
  ELZ47_RS02075 (NCTC10904_00412) sufD 411167..412429 (+) 1263 WP_126435144.1 Fe-S cluster assembly protein SufD -
  ELZ47_RS02080 (NCTC10904_00413) - 412470..413702 (+) 1233 WP_126435146.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28911.50 Da        Isoelectric Point: 3.9791

>NTDB_id=1117796 ELZ47_RS02060 WP_125445632.1 408356..409108(+) (mecA) [Streptococcus sanguinis strain NCTC 10904]
MEMKQISDSTIKITIQLEDLEERGMEMADFLVPQEKTEEFFYTILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKL
DKNLSFEDLADLPDMDELSHMSPDEFLKTLEKSIFEKSKEDIEAVQSLETAEAEEREQLSQEEADEQSAENAERYIYYIL
RFEDIKAAAAFAQTVDYKIDLSELYKYDSAYYLTILVDVEGFPERYPAWLLAKMREFADDSDITRAVLQEHGHLLLVTDA
VSGLQKVECL

Nucleotide


Download         Length: 753 bp        

>NTDB_id=1117796 ELZ47_RS02060 WP_125445632.1 408356..409108(+) (mecA) [Streptococcus sanguinis strain NCTC 10904]
ATGGAAATGAAACAGATTAGTGATTCGACCATAAAAATCACGATTCAGCTGGAAGATTTGGAAGAGCGTGGCATGGAAAT
GGCCGATTTCTTGGTCCCCCAAGAAAAGACAGAAGAGTTTTTCTATACCATCTTAGATGAGTTGGAAATGCCGGATAATT
TTTTGGACAGCGGTATGCTGAGTTTTCGAGTGACGCCTAAGCCAGATAAGGTGGATGTTTTTGTTACCAAATCTAAATTG
GATAAGAATCTGAGTTTTGAGGATTTGGCAGATCTGCCAGACATGGACGAGCTGTCTCATATGTCTCCAGATGAATTCCT
CAAGACACTAGAAAAGAGCATTTTTGAAAAGAGTAAGGAAGACATAGAAGCAGTCCAATCTTTGGAAACAGCCGAAGCAG
AGGAAAGGGAGCAGCTTTCTCAGGAGGAGGCTGATGAGCAGTCAGCAGAAAATGCAGAGCGTTACATTTACTATATCCTG
CGTTTTGAAGATATTAAGGCTGCTGCGGCCTTTGCCCAGACGGTGGACTATAAGATTGACTTATCAGAGCTTTATAAGTA
TGATTCAGCTTATTATTTGACGATTTTAGTAGATGTTGAGGGCTTTCCAGAGCGCTATCCAGCTTGGCTCTTGGCCAAGA
TGCGTGAATTCGCAGATGACTCAGATATCACTCGGGCAGTGCTGCAGGAGCACGGTCATCTGCTTTTGGTGACAGATGCG
GTCTCCGGTCTGCAGAAGGTTGAATGCCTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

68.826

98.8

0.68
  mecA Streptococcus pneumoniae D39

68.826

98.8

0.68
  mecA Streptococcus pneumoniae R6

68.826

98.8

0.68
  mecA Streptococcus pneumoniae TIGR4

68.421

98.8

0.676
  mecA Streptococcus mutans UA159

49.798

98.8

0.492
  mecA Streptococcus thermophilus LMD-9

48.996

99.6

0.488
  mecA Streptococcus thermophilus LMG 18311

48.594

99.6

0.484

Multiple sequence alignment