Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   EQB41_RS00500 Genome accession   NZ_LR129840
Coordinates   78085..79434 (+) Length   449 a.a.
NCBI ID   WP_050107888.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4496 isolate 4496     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 73085..84434
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQB41_RS00475 plsX 73206..74198 (+) 993 WP_000717458.1 phosphate acyltransferase PlsX -
  EQB41_RS00480 - 74204..74437 (+) 234 WP_000136447.1 acyl carrier protein -
  EQB41_RS00485 - 74474..74773 (+) 300 Protein_90 transposase family protein -
  EQB41_RS00490 blpU 74976..75206 (+) 231 WP_127820691.1 bacteriocin-like peptide BlpU -
  EQB41_RS12560 - 75209..75334 (+) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  EQB41_RS00495 comA 75919..78072 (+) 2154 WP_000668306.1 peptide cleavage/export ABC transporter ComA Regulator
  EQB41_RS00500 comB 78085..79434 (+) 1350 WP_050107888.1 competence pheromone export protein ComB Regulator
  EQB41_RS00505 purC 79604..80311 (+) 708 WP_000043300.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  EQB41_RS12685 - 80322..80432 (+) 111 WP_078065395.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  EQB41_RS00515 - 80513..84238 (+) 3726 WP_127820692.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49557.39 Da        Isoelectric Point: 5.5485

>NTDB_id=1116173 EQB41_RS00500 WP_050107888.1 78085..79434(+) (comB) [Streptococcus pneumoniae strain 4496 isolate 4496]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGHQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQSEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1116173 EQB41_RS00500 WP_050107888.1 78085..79434(+) (comB) [Streptococcus pneumoniae strain 4496 isolate 4496]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCCAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCCACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAATCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCTTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATTGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTATGGGGTGGAAGGCCG
TTTACAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

99.109

100

0.991
  comB Streptococcus pneumoniae Rx1

98.886

100

0.989
  comB Streptococcus pneumoniae D39

98.886

100

0.989
  comB Streptococcus pneumoniae R6

98.886

100

0.989
  comB Streptococcus mitis SK321

94.655

100

0.947
  comB Streptococcus mitis NCTC 12261

94.209

100

0.942
  comB Streptococcus gordonii str. Challis substr. CH1

55.111

100

0.552

Multiple sequence alignment