Detailed information
Bioinformatically predicted
Overview
| Name | comFC/cflB | Type | Machinery gene |
| Locus tag | HAS68_RS03195 | Genome accession | NZ_CP002007 |
| Coordinates | 607831..608496 (+) | Length | 221 a.a. |
| NCBI ID | WP_004194119.1 | Uniprot ID | A0A140EWV9 |
| Organism | Streptococcus suis 05HAS68 | ||
| Function | ssDNA transport into the cell (predicted from homology) DNA binding and uptake |
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Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 570662..607838 | 607831..608496 | flank | -7 |
Gene organization within MGE regions
Location: 570662..608496
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HAS68_RS03025 (HAS68_0529) | - | 570662..571606 (+) | 945 | WP_024409330.1 | IS30 family transposase | - |
| HAS68_RS11705 (HAS68_0530) | - | 571608..573008 (+) | 1401 | WP_238580467.1 | DNA methyltransferase | - |
| HAS68_RS11710 (HAS68_0531) | - | 572998..574278 (+) | 1281 | WP_238580468.1 | type IIL restriction-modification enzyme MmeI | - |
| HAS68_RS03035 (HAS68_0532) | - | 574275..576197 (+) | 1923 | WP_002935380.1 | DEAD/DEAH box helicase family protein | - |
| HAS68_RS03040 (HAS68_0533) | - | 576194..576484 (+) | 291 | WP_002935381.1 | hypothetical protein | - |
| HAS68_RS03045 (HAS68_0534) | - | 576474..577352 (+) | 879 | WP_029694137.1 | GIY-YIG nuclease family protein | - |
| HAS68_RS03050 (HAS68_0535) | - | 577677..578423 (+) | 747 | WP_002935387.1 | hypothetical protein | - |
| HAS68_RS03055 | tnpA | 578581..579112 (+) | 532 | Protein_562 | IS200/IS605 family transposase | - |
| HAS68_RS03060 (HAS68_0536) | - | 579275..580993 (-) | 1719 | WP_002935389.1 | phospho-sugar mutase | - |
| HAS68_RS03065 (HAS68_0537) | - | 581084..581653 (-) | 570 | WP_002935390.1 | ECF transporter S component | - |
| HAS68_RS03070 (HAS68_0538) | coaC | 581640..582188 (-) | 549 | WP_002935392.1 | phosphopantothenoylcysteine decarboxylase | - |
| HAS68_RS03075 (HAS68_0539) | - | 582181..582876 (-) | 696 | WP_022540619.1 | phosphopantothenate--cysteine ligase | - |
| HAS68_RS03080 (HAS68_0540) | - | 583380..585050 (+) | 1671 | WP_002935394.1 | formate--tetrahydrofolate ligase | - |
| HAS68_RS03085 (HAS68_0541) | - | 585094..585903 (-) | 810 | WP_002935395.1 | PrsW family glutamic-type intramembrane protease | - |
| HAS68_RS03090 (HAS68_0542) | - | 586120..587431 (+) | 1312 | Protein_569 | FAD-containing oxidoreductase | - |
| HAS68_RS03095 (HAS68_0543) | - | 587678..588418 (-) | 741 | WP_225585614.1 | PrsW family glutamic-type intramembrane protease | - |
| HAS68_RS03100 (HAS68_0544) | - | 588687..589304 (+) | 618 | WP_002935402.1 | DUF5052 family protein | - |
| HAS68_RS03105 (HAS68_0545) | - | 589305..589814 (+) | 510 | WP_002935404.1 | GNAT family N-acetyltransferase | - |
| HAS68_RS03110 (HAS68_0546) | - | 589804..590457 (+) | 654 | WP_002935405.1 | DNA alkylation repair protein | - |
| HAS68_RS03115 (HAS68_0547) | - | 590468..590755 (+) | 288 | WP_002935406.1 | DUF1905 domain-containing protein | - |
| HAS68_RS03120 (HAS68_0548) | - | 591052..591828 (-) | 777 | WP_002935416.1 | glycyl-radical enzyme activating protein | - |
| HAS68_RS03125 (HAS68_0549) | - | 591960..592703 (+) | 744 | WP_002935421.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| HAS68_RS03130 (HAS68_0550) | - | 592716..593690 (+) | 975 | WP_002935426.1 | sugar-binding transcriptional regulator | - |
| HAS68_RS03135 (HAS68_0551) | - | 593877..594200 (+) | 324 | WP_002935429.1 | PTS lactose/cellobiose transporter subunit IIA | - |
| HAS68_RS03140 (HAS68_0552) | - | 594233..594538 (+) | 306 | WP_002935430.1 | PTS sugar transporter subunit IIB | - |
| HAS68_RS03145 (HAS68_0553) | - | 594551..595852 (+) | 1302 | WP_002935431.1 | PTS sugar transporter subunit IIC | - |
| HAS68_RS03150 (HAS68_0554) | - | 596004..598448 (+) | 2445 | WP_002935432.1 | glycyl radical protein | - |
| HAS68_RS03155 (HAS68_0555) | - | 598463..599131 (+) | 669 | WP_002935438.1 | fructose-6-phosphate aldolase | - |
| HAS68_RS03160 (HAS68_0556) | - | 599163..600119 (+) | 957 | WP_002935440.1 | iron-containing alcohol dehydrogenase | - |
| HAS68_RS03165 (HAS68_0557) | - | 600240..601334 (+) | 1095 | WP_002935441.1 | glycerol dehydrogenase | - |
| HAS68_RS03170 (HAS68_0558) | - | 601503..602579 (+) | 1077 | WP_002935442.1 | aspartate-semialdehyde dehydrogenase | - |
| HAS68_RS03175 (HAS68_0559) | dapA | 602652..603587 (+) | 936 | WP_002935444.1 | 4-hydroxy-tetrahydrodipicolinate synthase | - |
| HAS68_RS11065 | - | 603845..604036 (+) | 192 | Protein_587 | aquaporin | - |
| HAS68_RS03180 (HAS68_0560) | - | 604381..605583 (+) | 1203 | WP_009909264.1 | IS110-like element ISSsu7 family transposase | - |
| HAS68_RS03185 (HAS68_0561) | - | 605857..606489 (-) | 633 | WP_004194123.1 | YigZ family protein | - |
| HAS68_RS03190 (HAS68_0562) | comFA/cflA | 606546..607838 (+) | 1293 | WP_004194121.1 | DEAD/DEAH box helicase | Machinery gene |
| HAS68_RS03195 (HAS68_0563) | comFC/cflB | 607831..608496 (+) | 666 | WP_004194119.1 | ComF family protein | Machinery gene |
Sequence
Protein
Download Length: 221 a.a. Molecular weight: 25748.55 Da Isoelectric Point: 8.2726
>NTDB_id=111596 HAS68_RS03195 WP_004194119.1 607831..608496(+) (comFC/cflB) [Streptococcus suis 05HAS68]
MSNCLLCGQAMKNKTRFSDLIFFSKEKSGICEECFSTFEEIAEQHCPHCYKNGESESCKDCQYWQNQGKPVVHTALYQYN
QAMAHYFSRYKFQGDYVLRNIFAKKLRIALSQFPDYTIVPIPISQKRLSERGFNQVEGLLDATNIPYQSLLGKYESQKQS
SKNRAERLEAKQMFYLLDEKEVPEKILLFDDIYTTGATIQLAVELFMKIGRKEIKTFSLTR
MSNCLLCGQAMKNKTRFSDLIFFSKEKSGICEECFSTFEEIAEQHCPHCYKNGESESCKDCQYWQNQGKPVVHTALYQYN
QAMAHYFSRYKFQGDYVLRNIFAKKLRIALSQFPDYTIVPIPISQKRLSERGFNQVEGLLDATNIPYQSLLGKYESQKQS
SKNRAERLEAKQMFYLLDEKEVPEKILLFDDIYTTGATIQLAVELFMKIGRKEIKTFSLTR
Nucleotide
Download Length: 666 bp
>NTDB_id=111596 HAS68_RS03195 WP_004194119.1 607831..608496(+) (comFC/cflB) [Streptococcus suis 05HAS68]
ATGTCTAATTGTCTATTGTGCGGTCAAGCTATGAAAAATAAAACAAGATTTTCAGATCTCATCTTCTTTAGTAAAGAAAA
ATCGGGCATCTGTGAAGAATGTTTTTCGACTTTTGAGGAAATAGCAGAGCAACACTGTCCACATTGTTATAAAAATGGAG
AATCGGAAAGTTGCAAGGATTGTCAGTACTGGCAGAATCAAGGGAAACCAGTTGTCCACACAGCTTTGTACCAATATAAT
CAAGCGATGGCACATTATTTTAGTCGCTACAAATTTCAAGGAGACTATGTTTTAAGAAATATTTTTGCTAAAAAGCTTAG
AATAGCGTTAAGCCAATTTCCTGACTACACAATTGTTCCCATACCAATTAGTCAAAAACGACTATCAGAACGCGGTTTTA
ATCAAGTGGAAGGACTTTTGGATGCTACAAATATTCCTTATCAGTCCCTTCTTGGAAAGTATGAAAGCCAAAAACAATCA
TCTAAAAATCGTGCAGAGAGACTAGAAGCAAAACAGATGTTCTATCTATTAGATGAAAAAGAAGTGCCAGAAAAAATATT
ATTATTCGACGATATATATACAACAGGAGCCACAATCCAACTTGCTGTAGAACTTTTCATGAAAATTGGTAGGAAAGAAA
TCAAAACATTTTCACTAACACGATAA
ATGTCTAATTGTCTATTGTGCGGTCAAGCTATGAAAAATAAAACAAGATTTTCAGATCTCATCTTCTTTAGTAAAGAAAA
ATCGGGCATCTGTGAAGAATGTTTTTCGACTTTTGAGGAAATAGCAGAGCAACACTGTCCACATTGTTATAAAAATGGAG
AATCGGAAAGTTGCAAGGATTGTCAGTACTGGCAGAATCAAGGGAAACCAGTTGTCCACACAGCTTTGTACCAATATAAT
CAAGCGATGGCACATTATTTTAGTCGCTACAAATTTCAAGGAGACTATGTTTTAAGAAATATTTTTGCTAAAAAGCTTAG
AATAGCGTTAAGCCAATTTCCTGACTACACAATTGTTCCCATACCAATTAGTCAAAAACGACTATCAGAACGCGGTTTTA
ATCAAGTGGAAGGACTTTTGGATGCTACAAATATTCCTTATCAGTCCCTTCTTGGAAAGTATGAAAGCCAAAAACAATCA
TCTAAAAATCGTGCAGAGAGACTAGAAGCAAAACAGATGTTCTATCTATTAGATGAAAAAGAAGTGCCAGAAAAAATATT
ATTATTCGACGATATATATACAACAGGAGCCACAATCCAACTTGCTGTAGAACTTTTCATGAAAATTGGTAGGAAAGAAA
TCAAAACATTTTCACTAACACGATAA
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comFC/cflB | Streptococcus mitis SK321 |
49.083 |
98.643 |
0.484 |
| comFC/cflB | Streptococcus pneumoniae TIGR4 |
49.083 |
98.643 |
0.484 |
| comFC/cflB | Streptococcus pneumoniae Rx1 |
49.083 |
98.643 |
0.484 |
| comFC/cflB | Streptococcus pneumoniae D39 |
49.083 |
98.643 |
0.484 |
| comFC/cflB | Streptococcus pneumoniae R6 |
49.083 |
98.643 |
0.484 |
| comFC/cflB | Streptococcus mitis NCTC 12261 |
49.083 |
98.643 |
0.484 |