Detailed information NTG1114551

Bioinformatically predicted

Overview

• Name: comB
• Type: Regulator
• Locus tag: A66_RS00280
• Genome accession: NZ_LN847353
• Coordinates: 46773..48122 (+)
• Length: 449 a.a.
• NCBI ID: WP_000801611.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain A66
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 41773..53122

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A66_RS10520	-	42680..43162 (+)	483	WP_001232094.1	stage II sporulation protein M	-
A66_RS00265 (A66_00051)	-	43159..43755 (+)	597	WP_000687787.1	ATP-binding cassette domain-containing protein	-
A66_RS00270	-	43736..44227 (+)	492	WP_000671990.1	hypothetical protein	-
A66_RS00275 (A66_00053)	comA	44607..46760 (+)	2154	WP_053039413.1	peptide cleavage/export ABC transporter ComA	Regulator
A66_RS00280 (A66_00054)	comB	46773..48122 (+)	1350	WP_000801611.1	competence pheromone export protein ComB	Regulator
A66_RS00285 (A66_00055)	purC	48292..48999 (+)	708	WP_000043300.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
A66_RS12825	-	49010..49144 (+)	135	WP_000429436.1	hypothetical protein	-
A66_RS00295 (A66_00056)	-	49201..52926 (+)	3726	WP_000361194.1	phosphoribosylformylglycinamidine synthase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 49601.49 Da
• Isoelectric Point: 5.5642

>NTDB_id=1114551 A66_RS00280 WP_000801611.1 46773..48122(+) (comB) [Streptococcus pneumoniae strain A66]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKVTASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKYVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide

• Length: 1350 bp

>NTDB_id=1114551 A66_RS00280 WP_000801611.1 46773..48122(+) (comB) [Streptococcus pneumoniae strain A66]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTTGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCCAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATTTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAGTTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCTTATCTAAGTTCAAAATATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB	Streptococcus pneumoniae TIGR4	100	100	1
comB	Streptococcus pneumoniae Rx1	98.886	100	0.989
comB	Streptococcus pneumoniae D39	98.886	100	0.989
comB	Streptococcus pneumoniae R6	98.886	100	0.989
comB	Streptococcus mitis SK321	94.655	100	0.947
comB	Streptococcus mitis NCTC 12261	94.209	100	0.942
comB	Streptococcus gordonii str. Challis substr. CH1	55.111	100	0.552