Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LACPI_RS11420 Genome accession   NZ_LN774769
Coordinates   2344401..2345648 (+) Length   415 a.a.
NCBI ID   WP_047916410.1    Uniprot ID   A0A0D6DZL9
Organism   Lactococcus piscium MKFS47     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2339401..2350648
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LACPI_RS11400 (LACPI_2235) - 2341192..2341515 (-) 324 WP_047916406.1 hypothetical protein -
  LACPI_RS11405 (LACPI_2236) - 2341757..2342617 (-) 861 WP_047916407.1 hypothetical protein -
  LACPI_RS11410 (LACPI_2237) - 2342856..2343533 (-) 678 WP_099046828.1 YoaK family protein -
  LACPI_RS11415 (LACPI_2238) rlmH 2343626..2344102 (-) 477 WP_047916409.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LACPI_RS11420 (LACPI_2239) htrA 2344401..2345648 (+) 1248 WP_047916410.1 S1C family serine protease Regulator
  LACPI_RS11425 (LACPI_2240) - 2345735..2346064 (-) 330 WP_047916411.1 bacteriocin immunity protein -
  LACPI_RS11435 (LACPI_2241) - 2346406..2347356 (-) 951 WP_047914556.1 IS30 family transposase -
  LACPI_RS11440 (LACPI_2242) - 2347534..2348532 (+) 999 WP_047916412.1 glycosyltransferase family 4 protein -
  LACPI_RS11445 (LACPI_2243) - 2348635..2349966 (+) 1332 WP_047916413.1 glycosyltransferase family 4 protein -
  LACPI_RS11450 (LACPI_2244) - 2350025..2350249 (+) 225 WP_047916414.1 DUF1797 family protein -
  LACPI_RS11455 (LACPI_2245) - 2350300..2350566 (-) 267 WP_047916415.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 43089.38 Da        Isoelectric Point: 5.9639

>NTDB_id=1114004 LACPI_RS11420 WP_047916410.1 2344401..2345648(+) (htrA) [Lactococcus piscium MKFS47]
MKTNKKTAAKLITAGIIGGAVALGGNVVYDHFNTTGTSLNTSSTATKVDNTAYKVTSDTTKAISKVSDAVVSVINYQKAP
ESGSSIDDLFGDRDNATKKDDAKEQPAAEGSGVIYKKDGDTAYVVTNNHVVDGASSLEILLANGNKVKGTLVGKDAYSDL
AVIKMAAKDVSKVATFGDSTKLTVGEPAIAIGSPLGSQYANSATEGIISSLSRQVIMKNESNETVNINALQTDAAINPGN
SGGALVNVEGQVIGINSSKISATGASSSDVSVEGMGFAIPSNDVVSIISKLEKDGEIKRPALGVQMLDLASISSQNQAQL
KLPNSVTAGVVIAKVQDGLPAAAAGLKKYDVITKIGDTKVTSGTELQTALYKYNIGDSMKITYYRDGKENTATIKLDNTS
DKLKFDDAEKKNTDK

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=1114004 LACPI_RS11420 WP_047916410.1 2344401..2345648(+) (htrA) [Lactococcus piscium MKFS47]
ATGAAAACAAATAAAAAAACAGCTGCAAAATTAATCACTGCTGGTATCATAGGTGGTGCTGTCGCTCTAGGTGGTAACGT
CGTTTATGACCACTTTAACACGACTGGTACATCCCTAAATACTAGCAGTACTGCTACTAAGGTTGATAATACAGCCTACA
AGGTTACAAGTGACACAACCAAAGCAATCAGTAAAGTATCTGATGCCGTCGTCTCTGTTATCAACTACCAAAAAGCACCC
GAAAGCGGGTCTTCCATCGATGATCTCTTTGGCGACCGTGATAATGCGACAAAGAAAGATGACGCAAAAGAACAACCTGC
AGCAGAAGGATCTGGGGTCATCTATAAAAAAGATGGCGATACTGCCTATGTTGTCACCAATAACCATGTTGTAGACGGTG
CTAGCTCGCTAGAAATCCTGCTTGCTAACGGCAATAAAGTGAAAGGTACATTGGTTGGTAAAGATGCCTATAGTGATTTA
GCTGTCATCAAGATGGCTGCAAAAGATGTCTCTAAAGTGGCAACTTTTGGTGACTCAACAAAACTGACTGTGGGTGAACC
TGCCATCGCAATCGGCTCTCCTCTGGGCAGCCAATACGCAAACTCAGCAACTGAAGGGATTATCTCTAGTCTCTCAAGAC
AAGTCATCATGAAAAACGAAAGTAATGAGACGGTTAATATTAATGCCCTACAAACAGACGCTGCGATAAATCCTGGTAAC
TCTGGTGGTGCACTCGTTAATGTAGAGGGACAAGTCATCGGCATTAACTCAAGTAAAATTTCAGCAACAGGTGCCTCTTC
AAGTGATGTTTCTGTTGAAGGAATGGGATTTGCTATCCCGTCAAATGATGTTGTCAGCATCATCAGTAAACTTGAAAAAG
ATGGTGAGATCAAACGTCCAGCACTAGGTGTCCAAATGCTTGATCTTGCAAGCATCAGCTCGCAAAATCAAGCCCAACTC
AAACTCCCTAACTCAGTCACTGCTGGTGTTGTGATTGCCAAGGTTCAAGATGGTCTTCCTGCTGCTGCTGCTGGTCTTAA
GAAATATGATGTCATCACAAAAATTGGGGATACCAAGGTAACAAGTGGTACTGAACTCCAGACAGCACTTTACAAATATA
ATATTGGGGATAGTATGAAAATCACCTATTATCGTGATGGTAAAGAGAACACTGCCACCATTAAACTAGATAATACATCA
GATAAGTTAAAATTTGATGATGCTGAGAAGAAAAATACTGATAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(300-396)

Trypsin-like peptidase domain (Trypsin_2)

(110-255)

Peptidase family M50 (Peptidase_M50)

(285-401)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D6DZL9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.726

96.867

0.53
  htrA Streptococcus mutans UA159

55.585

90.602

0.504
  htrA Streptococcus mitis NCTC 12261

53.022

87.711

0.465
  htrA Streptococcus pneumoniae TIGR4

52.661

86.024

0.453
  htrA Streptococcus pneumoniae Rx1

52.661

86.024

0.453
  htrA Streptococcus pneumoniae D39

52.661

86.024

0.453
  htrA Streptococcus pneumoniae R6

52.661

86.024

0.453

Multiple sequence alignment