Detailed information NTG0111299

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: H346_RS0102790
• Genome accession: NZ_AUKZ01000006
• Coordinates: 81438..82349 (+)
• Length: 303 a.a.
• NCBI ID: WP_027969744.1
• Uniprot ID: -
• Organism: Streptococcus castoreus DSM 17536
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 76438..87349

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H346_RS10780	-	77082..77249 (+)	168	WP_244147246.1	hypothetical protein	-
H346_RS0102765	purE	77466..77954 (+)	489	WP_027969739.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
H346_RS0102770	purK	77941..79023 (+)	1083	WP_027969740.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
H346_RS0102775	-	79034..79261 (+)	228	WP_027969741.1	hypothetical protein	-
H346_RS0102780	-	79258..80004 (+)	747	WP_027969742.1	hypothetical protein	-
H346_RS0102785	purB	80016..81308 (+)	1293	WP_027969743.1	adenylosuccinate lyase	-
H346_RS0102790	comR	81438..82349 (+)	912	WP_027969744.1	helix-turn-helix domain-containing protein	Regulator
H346_RS10710	comS	82440..82532 (+)	93	WP_208595719.1	quorum-sensing system DWW-type pheromone	Regulator
H346_RS0102800	ruvB	82595..83602 (+)	1008	WP_027969745.1	Holliday junction branch migration DNA helicase RuvB	-
H346_RS0102805	-	83741..84178 (+)	438	WP_027969746.1	low molecular weight protein-tyrosine-phosphatase	-
H346_RS0102810	-	84203..84604 (+)	402	WP_027969747.1	MORN repeat-containing protein	-
H346_RS0102815	-	84601..86376 (+)	1776	WP_027969748.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35632.03 Da
• Isoelectric Point: 4.6636

>NTDB_id=111299 H346_RS0102790 WP_027969744.1 81438..82349(+) (comR) [Streptococcus castoreus DSM 17536]
MLEYFGEKVRGLRHEKRISREDLCGDESELSVRQLARIELGQSIPSLAKVIFIAKALDVSVGYLTDGASLELPKRYKELK
YLILRTPTYMDDGKLQLREEQFDEIFEDYYEQLPEEEQLIIDCLQATLDTLLSGNINFGIDLLQEYFKQIKSKSRFREND
LILIELYLAYLDIEGLNGQYSDKSFNNSLLDILLHQFESFELDELFIMNKIIIGISSLSLKNDKLDNLEKTIEMSQKIMA
KIQDWNRMPILKLIEWKYFLIKQKNKQKAKEAFVKACLFAQVTGDKYLEKQLNEEWERDINSY

Nucleotide

• Length: 912 bp

>NTDB_id=111299 H346_RS0102790 WP_027969744.1 81438..82349(+) (comR) [Streptococcus castoreus DSM 17536]
ATGTTAGAATATTTTGGTGAAAAAGTGAGGGGACTTAGGCATGAAAAAAGGATTAGCAGAGAGGACTTATGTGGGGATGA
GTCTGAGTTATCCGTTCGTCAGTTAGCACGAATAGAGTTGGGGCAATCAATACCAAGCTTGGCAAAAGTTATATTTATTG
CGAAAGCCCTGGATGTTAGTGTTGGTTATTTAACAGATGGAGCTAGTTTGGAATTGCCCAAACGTTACAAGGAGTTGAAA
TATTTAATTTTGAGAACACCAACCTATATGGATGATGGGAAATTACAACTTCGAGAAGAACAATTTGACGAAATTTTTGA
AGATTACTACGAACAACTACCTGAGGAAGAGCAGTTAATCATTGATTGTTTACAGGCGACCTTAGATACTTTATTGAGTG
GGAATATCAATTTTGGGATTGATTTGTTGCAAGAATATTTTAAACAAATAAAAAGTAAGTCTCGATTTAGAGAAAATGAC
CTAATACTTATTGAATTGTATTTGGCTTATCTTGATATTGAAGGTTTGAATGGTCAGTATTCAGATAAATCTTTTAATAA
TTCATTGCTAGATATTCTTTTGCATCAATTTGAGAGTTTTGAATTAGACGAATTATTTATAATGAATAAAATAATTATTG
GTATTTCTTCACTAAGTCTAAAAAATGATAAACTTGATAATCTGGAAAAGACTATTGAAATGAGTCAAAAGATTATGGCA
AAAATTCAAGACTGGAATAGGATGCCTATACTAAAGTTAATAGAATGGAAATACTTTTTAATTAAACAAAAAAATAAACA
AAAAGCAAAAGAAGCGTTTGTAAAGGCGTGTCTTTTTGCTCAAGTCACGGGTGATAAGTATTTGGAAAAACAATTAAATG
AAGAATGGGAAAGGGATATTAATAGTTATTAA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (27-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	83.168	100	0.832
comR	Streptococcus pyogenes MGAS315	55.15	99.34	0.548
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	48.288	96.37	0.465
comR	Streptococcus mutans UA159	47.157	98.68	0.465