Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   - Genome accession   NZ_AUKZ01000006
Coordinates   82440..82532 (+) Length   31 a.a.
NCBI ID   - Uniprot ID   -
Organism   Streptococcus castoreus DSM 17536     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context


Location: 77440..87532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H346_RS0102765 purE 77466..77954 (+) 489 WP_027969739.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  H346_RS0102770 purK 77941..79023 (+) 1083 WP_027969740.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  H346_RS0102775 - 79034..79261 (+) 228 WP_027969741.1 hypothetical protein -
  H346_RS0102780 - 79258..80004 (+) 747 WP_027969742.1 hypothetical protein -
  H346_RS0102785 purB 80016..81308 (+) 1293 WP_027969743.1 adenylosuccinate lyase -
  H346_RS0102790 comR 81438..82349 (+) 912 WP_027969744.1 helix-turn-helix domain-containing protein Regulator
  H346_RS10710 comS 82440..82532 (+) 93 WP_208595719.1 quorum-sensing system DWW-type pheromone Regulator
  H346_RS0102800 ruvB 82595..83602 (+) 1008 WP_027969745.1 Holliday junction branch migration DNA helicase RuvB -
  H346_RS0102805 - 83741..84178 (+) 438 WP_027969746.1 low molecular weight protein-tyrosine-phosphatase -
  H346_RS0102810 - 84203..84604 (+) 402 WP_027969747.1 MORN repeat-containing protein -
  H346_RS0102815 - 84601..86376 (+) 1776 WP_027969748.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 31 a.a.        Molecular weight: 3889.67 Da        Isoelectric Point: 9.6620

>NTDB_id=571 82440..82532(+) (comS) [Streptococcus castoreus DSM 17536]
MFKKYQYYFALIALLSFKAVQMISEVDWWRL

Nucleotide


Download         Length: 93 bp        

>NTDB_id=571 82440..82532(+) (comS) [Streptococcus castoreus DSM 17536]
ATGTTCAAAAAATATCAGTATTACTTTGCTCTTATTGCTTTATTGTCTTTTAAAGCTGTTCAAATGATCAGTGAAGTTGA
CTGGTGGCGCCTA

XIP


This gene is known to encode the precursor of σX inducing peptide (XIP), which involves in competence development. The mature XIP sequence is displayed as below:

EVDWWRL


Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

70.968

100

0.71

  comS Streptococcus pyogenes MGAS315

38.71

100

0.387


Multiple sequence alignment