Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   F601_RS0105095 Genome accession   NZ_AQYA01000030
Coordinates   102555..103307 (+) Length   250 a.a.
NCBI ID   WP_018164590.1    Uniprot ID   -
Organism   Streptococcus henryi DSM 19005     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 97555..108307
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F601_RS13085 - 98476..98670 (+) 195 WP_074485590.1 hypothetical protein -
  F601_RS0105080 - 98794..99534 (-) 741 WP_018164587.1 amino acid ABC transporter ATP-binding protein -
  F601_RS0105085 - 99534..101099 (-) 1566 WP_018164588.1 ABC transporter substrate-binding protein/permease -
  F601_RS0105090 - 101381..102220 (+) 840 WP_018164589.1 undecaprenyl-diphosphate phosphatase -
  F601_RS0105095 mecA 102555..103307 (+) 753 WP_018164590.1 adaptor protein MecA Regulator
  F601_RS0105100 - 103309..104466 (+) 1158 WP_018164591.1 glycosyltransferase family 4 protein -
  F601_RS0105105 sufC 104665..105435 (+) 771 WP_018164592.1 Fe-S cluster assembly ATPase SufC -
  F601_RS0105110 sufD 105470..106732 (+) 1263 WP_018164593.1 Fe-S cluster assembly protein SufD -
  F601_RS0105115 - 106784..108016 (+) 1233 WP_026183114.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28717.43 Da        Isoelectric Point: 4.1368

>NTDB_id=111272 F601_RS0105095 WP_018164590.1 102555..103307(+) (mecA) [Streptococcus henryi DSM 19005]
MEMKQISETTLKITISMEDLEEHGMELKDFLIPQEKTEEFFYNVMDELDLPDNFKNSGMLSFRVTPRKDRIDVFVTKSEI
NKDLNFEDLADLGDVSNMSPEDFFKTLKQSMRSKGDTDAHEKLEKIEEIMEAVADEAMNEQAVEESEEAVEPADYVHYVL
DFASLEDAVLFSKTVDFPVEASELYKQSDAYHMTVLLNLVNKPSYFANVMYARMLEHAAPGTKTRAYLQEHGVQLLMDDA
VQKLQLIDLV

Nucleotide


Download         Length: 753 bp        

>NTDB_id=111272 F601_RS0105095 WP_018164590.1 102555..103307(+) (mecA) [Streptococcus henryi DSM 19005]
ATGGAAATGAAACAAATCAGTGAGACGACACTGAAAATAACAATTAGCATGGAGGATTTGGAAGAACATGGCATGGAGCT
TAAGGACTTCCTTATCCCTCAAGAAAAGACTGAGGAGTTTTTCTATAACGTTATGGATGAACTTGATCTGCCTGATAATT
TCAAAAACAGTGGTATGCTCAGTTTTCGCGTGACACCAAGGAAAGATCGTATTGATGTCTTTGTGACTAAGTCTGAAATT
AATAAAGATTTAAACTTTGAAGATTTAGCAGATCTTGGTGATGTATCAAATATGTCCCCAGAAGATTTTTTCAAGACATT
GAAACAAAGCATGCGCTCTAAAGGTGACACGGATGCCCATGAAAAGCTTGAAAAAATCGAAGAAATAATGGAAGCTGTCG
CGGACGAAGCTATGAATGAGCAGGCTGTTGAAGAGTCTGAGGAAGCAGTGGAACCAGCTGACTACGTTCACTATGTGTTG
GATTTTGCTAGTCTGGAAGATGCTGTACTTTTTTCTAAAACGGTTGATTTTCCTGTTGAAGCTTCAGAGTTATATAAACA
GTCTGATGCTTATCATATGACTGTTTTGCTTAATTTAGTTAATAAACCAAGTTATTTTGCTAATGTCATGTATGCTCGTA
TGTTAGAACATGCAGCTCCTGGTACTAAAACACGCGCTTATCTCCAAGAACATGGCGTTCAGCTGTTAATGGATGATGCT
GTTCAAAAACTACAATTGATAGATTTGGTGTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

70.04

98.8

0.692
  mecA Streptococcus thermophilus LMD-9

60.976

98.4

0.6
  mecA Streptococcus thermophilus LMG 18311

60.163

98.4

0.592
  mecA Streptococcus pneumoniae Rx1

51.2

100

0.512
  mecA Streptococcus pneumoniae D39

51.2

100

0.512
  mecA Streptococcus pneumoniae R6

51.2

100

0.512
  mecA Streptococcus pneumoniae TIGR4

50.8

100

0.508

Multiple sequence alignment