Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   HMPREF9425_RS07585 Genome accession   NZ_GL831112
Coordinates   1571984..1572673 (-) Length   229 a.a.
NCBI ID   WP_003097952.1    Uniprot ID   -
Organism   Streptococcus vestibularis ATCC 49124     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1566984..1577673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9425_RS07565 (HMPREF9425_1584) dnaI 1567791..1568693 (-) 903 WP_003097946.1 primosomal protein DnaI -
  HMPREF9425_RS07570 (HMPREF9425_1585) - 1568697..1569872 (-) 1176 WP_003097948.1 DnaD domain protein -
  HMPREF9425_RS07575 (HMPREF9425_1586) nrdR 1569869..1570348 (-) 480 WP_003092257.1 transcriptional regulator NrdR -
  HMPREF9425_RS07580 (HMPREF9425_1587) covS 1570470..1571987 (-) 1518 WP_003097950.1 HAMP domain-containing sensor histidine kinase Regulator
  HMPREF9425_RS07585 (HMPREF9425_1588) covR 1571984..1572673 (-) 690 WP_003097952.1 response regulator transcription factor Regulator
  HMPREF9425_RS07590 (HMPREF9425_1589) - 1572830..1573366 (-) 537 WP_003097953.1 DUF177 domain-containing protein -
  HMPREF9425_RS07595 (HMPREF9425_1590) rsmG 1573665..1574378 (+) 714 WP_003097955.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  HMPREF9425_RS07600 (HMPREF9425_1591) - 1574447..1575810 (+) 1364 Protein_1546 TrkH family potassium uptake protein -
  HMPREF9425_RS07605 (HMPREF9425_1592) - 1575850..1576521 (+) 672 WP_003092220.1 potassium channel family protein -
  HMPREF9425_RS10405 - 1576538..1576708 (-) 171 Protein_1548 ascorbate 6-phosphate lactonase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26584.64 Da        Isoelectric Point: 4.6958

>NTDB_id=1111764 HMPREF9425_RS07585 WP_003097952.1 1571984..1572673(-) (covR) [Streptococcus vestibularis ATCC 49124]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKNTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEATKNAPAKASTYRDLKLDVQNRAVIRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1111764 HMPREF9425_RS07585 WP_003097952.1 1571984..1572673(-) (covR) [Streptococcus vestibularis ATCC 49124]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
TGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAAAAAATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCCGGTTTGGACCGTGGAGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACCTTCCGTCGACAAGATATCGAAGCTACTAAGAATGCACCAGCTAAAGCGTCAA
CCTATCGCGATTTGAAATTGGATGTTCAAAACCGTGCAGTTATTCGTGGTGATGAGGCGATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACTCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

96.943

100

0.969
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.228

99.563

0.659
  vicR Streptococcus mutans UA159

44.397

100

0.45
  micA Streptococcus pneumoniae Cp1015

43.043

100

0.432

Multiple sequence alignment