Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   HMPREF9425_RS07580 Genome accession   NZ_GL831112
Coordinates   1570470..1571987 (-) Length   505 a.a.
NCBI ID   WP_003097950.1    Uniprot ID   -
Organism   Streptococcus vestibularis ATCC 49124     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1565470..1576987
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9425_RS07555 (HMPREF9425_1582) - 1565663..1566310 (-) 648 WP_003092227.1 hypothetical protein -
  HMPREF9425_RS07560 (HMPREF9425_1583) der 1566375..1567685 (-) 1311 WP_003092252.1 ribosome biogenesis GTPase Der -
  HMPREF9425_RS07565 (HMPREF9425_1584) dnaI 1567791..1568693 (-) 903 WP_003097946.1 primosomal protein DnaI -
  HMPREF9425_RS07570 (HMPREF9425_1585) - 1568697..1569872 (-) 1176 WP_003097948.1 DnaD domain protein -
  HMPREF9425_RS07575 (HMPREF9425_1586) nrdR 1569869..1570348 (-) 480 WP_003092257.1 transcriptional regulator NrdR -
  HMPREF9425_RS07580 (HMPREF9425_1587) covS 1570470..1571987 (-) 1518 WP_003097950.1 HAMP domain-containing sensor histidine kinase Regulator
  HMPREF9425_RS07585 (HMPREF9425_1588) covR 1571984..1572673 (-) 690 WP_003097952.1 response regulator transcription factor Regulator
  HMPREF9425_RS07590 (HMPREF9425_1589) - 1572830..1573366 (-) 537 WP_003097953.1 DUF177 domain-containing protein -
  HMPREF9425_RS07595 (HMPREF9425_1590) rsmG 1573665..1574378 (+) 714 WP_003097955.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  HMPREF9425_RS07600 (HMPREF9425_1591) - 1574447..1575810 (+) 1364 Protein_1546 TrkH family potassium uptake protein -
  HMPREF9425_RS07605 (HMPREF9425_1592) - 1575850..1576521 (+) 672 WP_003092220.1 potassium channel family protein -
  HMPREF9425_RS10405 - 1576538..1576708 (-) 171 Protein_1548 ascorbate 6-phosphate lactonase -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57509.65 Da        Isoelectric Point: 5.0935

>NTDB_id=1111763 HMPREF9425_RS07580 WP_003097950.1 1570470..1571987(-) (covS) [Streptococcus vestibularis ATCC 49124]
MSKLFGKVTIRKKLTITAAVVFFIVLSMFTLVVVLSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPESLLSALY
SPKNIYGSMINGVLSEKHSLDGQVAVSNKLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKSVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLEFYYALKERLIFLLIFLEVGITVLVIAVTVVVLTSILRPMRQLHETMGIITDSPSDLELR
SKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQVITILIDNAVKY
SPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAGSETTTPQLED

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=1111763 HMPREF9425_RS07580 WP_003097950.1 1570470..1571987(-) (covS) [Streptococcus vestibularis ATCC 49124]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATAACAGCTGCTGTGGTCTTCTTTATTGTATTGTC
GATGTTCACTCTGGTTGTTGTTCTCTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAATCGCTTTTATCGGCCCTTTAT
TCACCGAAAAATATCTATGGATCAATGATTAATGGAGTGCTTTCTGAAAAGCATTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAAATTATATTCCAATCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTCGGTTTCCTATAAAGGTAAACGTGGTTTCTTATTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTTTACTATGCGTTAAA
AGAGCGTCTAATTTTTCTATTGATATTCCTTGAAGTAGGAATAACTGTCTTAGTTATTGCAGTAACTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTGCACGAAACGATGGGTATTATTACAGATTCGCCAAGTGACTTGGAGCTTCGT
TCTAAGATTGAGAGTCATGATGAGATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCAATTGCAGTTATTAAGGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTCCGTGTCCTACATGAAGACTACCAATTCTACCTCAATGATTTTGAGA
GTTCAGAGCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCAGTCAAGTAT
TCGCCTGTTAATAAGGAAATCCAGGTTACTATCAAGGCTCTGGAAGATGAGATGTTAGTACAGGTACAGGATAATGGTGA
GGGTATCTCCAAAGAAGATATTGAACATATCTTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAACCGTACGACAACCC
AATCTGGTGTGGGTATTGGCTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATTGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGGGTCAGAAACTACGACACCTCAACTTGAGGATTAA

Domains

Predicted by InterproScan.

ArlS sensor domain (ArlS_N)

(39-187)

HAMP domain (HAMP)

(213-265)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-493)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

95.817

99.406

0.952

Multiple sequence alignment