Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   HMPREF9425_RS05525 Genome accession   NZ_GL831112
Coordinates   1124536..1125951 (-) Length   471 a.a.
NCBI ID   WP_003097403.1    Uniprot ID   -
Organism   Streptococcus vestibularis ATCC 49124     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1119536..1130951
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9425_RS05495 (HMPREF9425_1153) - 1120065..1120463 (-) 399 WP_003097396.1 cytidine deaminase -
  HMPREF9425_RS05500 (HMPREF9425_1154) deoC 1120450..1121112 (-) 663 WP_003097397.1 deoxyribose-phosphate aldolase -
  HMPREF9425_RS05505 (HMPREF9425_1155) - 1121146..1122423 (-) 1278 WP_003097398.1 pyrimidine-nucleoside phosphorylase -
  HMPREF9425_RS05510 (HMPREF9425_1156) - 1122420..1123010 (-) 591 WP_003093879.1 class I SAM-dependent methyltransferase -
  HMPREF9425_RS05515 (HMPREF9425_1157) coaA 1123225..1124145 (+) 921 WP_037621505.1 type I pantothenate kinase -
  HMPREF9425_RS05520 (HMPREF9425_1158) rpsT 1124214..1124449 (+) 236 Protein_1124 30S ribosomal protein S20 -
  HMPREF9425_RS05525 (HMPREF9425_1159) ciaH 1124536..1125951 (-) 1416 WP_003097403.1 sensor histidine kinase Regulator
  HMPREF9425_RS05530 (HMPREF9425_1160) ciaR 1125941..1126615 (-) 675 WP_003093839.1 response regulator transcription factor Regulator
  HMPREF9425_RS05535 (HMPREF9425_1161) - 1126810..1128480 (-) 1671 WP_003097405.1 formate--tetrahydrofolate ligase -
  HMPREF9425_RS05540 (HMPREF9425_1162) - 1128675..1129358 (+) 684 WP_003094310.1 phosphopantothenate--cysteine ligase -
  HMPREF9425_RS05545 (HMPREF9425_1163) coaC 1129351..1129914 (+) 564 WP_003097406.1 phosphopantothenoylcysteine decarboxylase -
  HMPREF9425_RS05550 (HMPREF9425_1164) - 1129907..1130479 (+) 573 WP_037621508.1 ECF transporter S component -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53414.06 Da        Isoelectric Point: 6.8901

>NTDB_id=1111750 HMPREF9425_RS05525 WP_003097403.1 1124536..1125951(-) (ciaH) [Streptococcus vestibularis ATCC 49124]
MLTKCFNYLFMRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VNQNNTTTIYQAYDTKSSTAETPDSSGSKKESKKKSKMEDAPHDLSVAANTSVLVLDKNGEVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTENYRLITEKVDNNFYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSIVASLYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEALFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLDSSFFDTVFTNYAMIAEESEKGFTAQNQVGRSIQTDKTLLKQLMTILFDNAIKYTEDDGQVTFTVRTNDRHLYIT
VADNGPGIADEDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIIVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=1111750 HMPREF9425_RS05525 WP_003097403.1 1124536..1125951(-) (ciaH) [Streptococcus vestibularis ATCC 49124]
ATGCTGACTAAATGTTTCAATTATCTCTTCATGAGAATCAAGTCAGACGGCTTTAAGTCCTTCATCCATTTCTTTGCAAC
TTTTTCTGGTATTTTCCTTATCATGACTGTTATGATTTTGCAGATTCTGAGTTACGGTGTTTATTCCAATGTTGACTCTA
GTCTGAAAATGGCAGCGACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTATTTCTGACCTCTGAG
GTAAATCAAAATAATACGACAACCATTTATCAGGCTTATGATACTAAAAGTTCTACAGCTGAAACACCTGACTCGAGTGG
CTCTAAGAAAGAATCTAAGAAGAAATCAAAGATGGAAGATGCCCCACATGATTTATCTGTTGCTGCTAATACCAGTGTCT
TAGTACTTGATAAGAATGGAGAGGTCCTCAATGTCGTTGATAAATTTTCAAGCTTATCCAATCTACCAATAGATAAAAAT
AATATTGATGTTATCAGTAAGGGAAGTGCTCAGAACTATTTTGATCAAACAGAAAATTATCGCTTGATTACTGAAAAAGT
AGATAATAATTTCTATCCTGATGCTAAGTACCTTGTTATTGCAATCAATACGACGCAATTAGAAGAAGCCACTGAACGTT
ATGTAAAACTAATTGTCATTATGATGAGTTTTTTTTGGCTACTATCTATCGTAGCTAGTTTGTATTTGGCAAAATGGTCA
AGACGGCCTATACAGGAAAGTCTGGAGAAGCAGAAGGCATTTGTTGAGAATGCTAGCCACGAGTTGCGTACGCCACTTGC
TGTGATTCAAAACCGACTAGAGGCGCTTTTCCGTAAGCCTGAAAGTACCATTTTAGATAATTCAGAAAACATTGCTTCAA
GTCTTGATGAAGTCCGAAATATGCGTCTTTTGACGACCAATCTCTTGAATTTGGCTCGTCGTGATGATGGTATTAAACCA
GAAATTGAAACCTTAGATTCTTCTTTCTTTGATACAGTCTTTACCAATTATGCTATGATTGCTGAAGAAAGTGAAAAGGG
GTTTACTGCTCAAAATCAGGTTGGGCGCTCAATCCAAACTGATAAGACTCTATTGAAGCAGCTCATGACAATTTTATTCG
ATAATGCTATCAAATATACAGAAGATGATGGCCAGGTGACTTTCACCGTTCGTACTAATGATCGTCATCTTTATATTACA
GTGGCAGACAATGGCCCTGGTATTGCAGATGAAGATAAGAAAAAAATCTTTGATCGTTTCTACCGAGTAGACAAAGCTAG
AACTAGACAAAAAGGTGGTTTTGGGTTGGGCTTATCTTTAGCACAACAGATTGTTCTTGCTCTTAAAGGAACGATAATTG
TCAAGGACAATCAGCCGAAGGGGACTATTTTTGAAGTTAAAATTACCGGAGTCTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.696

95.117

0.539
  ciaH Streptococcus pneumoniae Rx1

50.769

96.603

0.49
  ciaH Streptococcus pneumoniae D39

50.769

96.603

0.49
  ciaH Streptococcus pneumoniae R6

50.769

96.603

0.49
  ciaH Streptococcus pneumoniae TIGR4

50.769

96.603

0.49

Multiple sequence alignment