Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   HMPREF9425_RS05265 Genome accession   NZ_GL831112
Coordinates   1073097..1073840 (+) Length   247 a.a.
NCBI ID   WP_003097341.1    Uniprot ID   -
Organism   Streptococcus vestibularis ATCC 49124     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1068097..1078840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9425_RS05250 (HMPREF9425_1101) - 1068104..1068466 (-) 363 WP_003097334.1 hypothetical protein -
  HMPREF9425_RS05255 (HMPREF9425_1102) - 1068593..1071637 (-) 3045 WP_003097336.1 SEC10/PgrA surface exclusion domain-containing protein -
  HMPREF9425_RS05260 (HMPREF9425_1103) - 1071797..1072123 (+) 327 WP_003097338.1 helix-turn-helix domain-containing protein -
  HMPREF9425_RS05265 (HMPREF9425_1105) comE/blpR 1073097..1073840 (+) 744 WP_003097341.1 response regulator transcription factor Regulator
  HMPREF9425_RS05270 (HMPREF9425_1106) - 1073850..1075157 (+) 1308 WP_003097342.1 sensor histidine kinase -
  HMPREF9425_RS05275 (HMPREF9425_1107) - 1075398..1075964 (-) 567 WP_003097344.1 hypothetical protein -
  HMPREF9425_RS05280 (HMPREF9425_1108) - 1076656..1077894 (+) 1239 WP_003097346.1 hypothetical protein -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28810.22 Da        Isoelectric Point: 6.1726

>NTDB_id=1111748 HMPREF9425_RS05265 WP_003097341.1 1073097..1073840(+) (comE/blpR) [Streptococcus vestibularis ATCC 49124]
MLNIFILEDEFLQQTRIETVIKDVIAKKSLKCKGPEIFGKPSQLLDAITERGYHQLFFLDIEIKGEEKKGLDIAKEIRKK
DPNATIVFVTTHSEFMPVTFKYRVAALDFIDKALDDEDFYERVHLAIEYTMDKMGATIAQDSFTFETATAHVQVPFNNIL
FFETSPTIHKVILHTKEERMEFYASISEVERADDRLYRCHRSFIVNPENIIRINKEEKIVMFENNNECPISRTKYKGLLE
KVKSLKS

Nucleotide


Download         Length: 744 bp        

>NTDB_id=1111748 HMPREF9425_RS05265 WP_003097341.1 1073097..1073840(+) (comE/blpR) [Streptococcus vestibularis ATCC 49124]
TTGTTAAATATTTTTATTTTAGAAGACGAATTTTTACAACAAACACGAATAGAGACCGTTATTAAGGATGTTATTGCAAA
AAAATCTCTAAAATGTAAAGGACCTGAGATTTTTGGAAAACCTAGCCAGCTACTTGACGCAATAACCGAAAGAGGTTATC
ATCAACTTTTCTTTTTAGATATTGAAATTAAAGGAGAAGAAAAAAAGGGGCTAGACATTGCAAAAGAAATTCGAAAAAAA
GACCCTAATGCAACAATTGTTTTTGTAACAACACATTCAGAATTTATGCCAGTCACTTTTAAATATAGAGTTGCTGCACT
AGATTTTATTGATAAAGCTTTGGATGATGAAGATTTTTATGAACGTGTTCATTTAGCAATTGAATATACCATGGATAAAA
TGGGTGCCACTATTGCCCAAGATTCATTTACTTTTGAAACAGCTACGGCCCATGTTCAAGTGCCTTTTAACAATATTTTA
TTTTTTGAAACATCTCCAACAATACATAAAGTTATTTTGCATACTAAAGAAGAACGCATGGAGTTCTACGCCAGTATTTC
AGAAGTTGAACGAGCTGATGATCGCCTGTATCGATGCCATCGTTCATTTATCGTTAATCCTGAAAATATCATAAGGATCA
ATAAAGAAGAGAAAATAGTAATGTTTGAAAATAATAATGAATGTCCCATTTCGCGTACGAAATATAAGGGCCTCCTAGAA
AAAGTTAAATCTCTGAAAAGCTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-241)

Response regulator receiver domain (Response_reg)

(4-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.942

97.571

0.526
  comE/comE1 Streptococcus equinus JB1

45.679

98.381

0.449
  comE/comE2 Streptococcus equinus JB1

39.431

99.595

0.393
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.247

100

0.372
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.247

100

0.372

Multiple sequence alignment