Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   HMPREF9319_RS04880 Genome accession   NZ_GL397128
Coordinates   1018569..1019909 (-) Length   446 a.a.
NCBI ID   WP_003064880.1    Uniprot ID   A0AAW6YHF0
Organism   Streptococcus equinus ATCC 700338     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1013569..1024909
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9319_RS04855 (HMPREF9319_1002) - 1014121..1015185 (-) 1065 WP_003064867.1 BMP family lipoprotein -
  HMPREF9319_RS04860 (HMPREF9319_1003) deoC 1015380..1016042 (-) 663 WP_003064871.1 deoxyribose-phosphate aldolase -
  HMPREF9319_RS04865 (HMPREF9319_1004) - 1016498..1017091 (-) 594 WP_003064873.1 class I SAM-dependent methyltransferase -
  HMPREF9319_RS04870 (HMPREF9319_1005) coaA 1017207..1018127 (+) 921 WP_003064875.1 type I pantothenate kinase -
  HMPREF9319_RS04875 (HMPREF9319_1006) rpsT 1018202..1018453 (+) 252 WP_003064878.1 30S ribosomal protein S20 -
  HMPREF9319_RS04880 (HMPREF9319_1007) ciaH 1018569..1019909 (-) 1341 WP_003064880.1 sensor histidine kinase Regulator
  HMPREF9319_RS04885 (HMPREF9319_1008) ciaR 1019899..1020573 (-) 675 WP_003064882.1 response regulator transcription factor Regulator
  HMPREF9319_RS04890 (HMPREF9319_1009) - 1020766..1023309 (-) 2544 WP_003064884.1 M1 family metallopeptidase -
  HMPREF9319_RS04895 (HMPREF9319_1010) phoU 1023532..1024185 (-) 654 WP_003064885.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 49991.74 Da        Isoelectric Point: 5.2300

>NTDB_id=1111688 HMPREF9319_RS04880 WP_003064880.1 1018569..1019909(-) (ciaH) [Streptococcus equinus ATCC 700338]
MLNKLQKKLSSGTFSHFFHFFAVFTGIFVIMTVIILQIMRYGLYSSVDTSLQNAADNADDYVARTMERSDTLQSDDSSTD
AFSGGTGSSGKAKPSTGGVGLSNVSVLLYDEDGKILNALDAFVQFGTLSTTFDEDSVGEIKEQKITTIFGQTEKYHVLAV
KVSSSEYPSIKYATFLVSVRQLDEANERYVTITITVMVIFWIISVVASVYLANWTRKPIMESYEKQKSFVENASHELRTP
LAVLQNRLESLFRRPDATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEDIQPATFNEIFENYDMIAEENG
KTFIGHNLAERPIKSDRTLLKQLMTILFDNAIKYTDDDGVIEFTVKTTDKQTILTVADNGPGISDADKVKIFDRFYRVDK
ARTRQKGGFGLGLSLAKQIVDVLKGDIQVKDNQPKGTIFEVRFNRH

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=1111688 HMPREF9319_RS04880 WP_003064880.1 1018569..1019909(-) (ciaH) [Streptococcus equinus ATCC 700338]
ATGCTGAATAAATTACAGAAAAAATTATCATCAGGGACATTTTCACATTTCTTTCATTTCTTTGCTGTCTTTACAGGGAT
TTTTGTCATCATGACAGTGATTATTTTGCAGATTATGCGTTATGGACTTTATTCCTCTGTTGATACGAGTTTGCAAAATG
CAGCAGACAATGCTGATGATTATGTCGCGCGAACTATGGAACGTAGTGATACTTTGCAATCGGACGATTCTTCTACGGAC
GCTTTTTCAGGAGGAACAGGTAGTTCTGGGAAAGCGAAACCTAGTACCGGCGGAGTTGGTCTAAGCAACGTTAGCGTTCT
TCTTTATGATGAAGACGGTAAAATTTTAAATGCTTTGGATGCTTTTGTTCAATTTGGAACCTTATCGACAACTTTTGATG
AAGATAGTGTCGGTGAAATCAAAGAACAGAAGATTACGACCATTTTTGGTCAAACCGAGAAATATCATGTGTTGGCTGTA
AAAGTGAGTAGTAGCGAGTATCCTAGTATAAAATACGCTACTTTCCTTGTTAGTGTTCGTCAGTTAGATGAAGCTAACGA
ACGATACGTGACAATTACGATTACTGTTATGGTTATTTTCTGGATTATTTCGGTCGTAGCAAGTGTTTATCTTGCCAATT
GGACAAGAAAACCAATTATGGAAAGCTATGAAAAACAAAAATCCTTTGTCGAAAATGCTAGTCATGAGTTGCGTACACCG
CTTGCTGTTTTGCAGAATCGTTTAGAAAGTCTCTTTAGGCGACCTGATGCTACAATTTTGGACAATAGTGAAAGTATTGC
TGCCAGTCTAGACGAAGTTCGAAATATGCGAATTCTGACCACAAATCTGTTAAATTTAGCACGTCGTGACGATGGTTTGA
AAGTTGAGTTAGAGGATATTCAACCAGCAACTTTCAATGAAATCTTTGAAAATTACGATATGATTGCTGAAGAAAATGGC
AAGACGTTTATCGGACATAATTTGGCAGAGCGACCAATCAAATCAGACCGTACATTGTTAAAACAACTGATGACTATCTT
ATTTGATAATGCCATAAAATATACCGACGATGATGGTGTCATTGAATTTACTGTTAAAACAACAGATAAACAAACAATTC
TGACAGTTGCTGATAACGGCCCAGGGATTAGCGACGCTGATAAAGTTAAGATTTTTGACCGTTTTTATCGTGTGGATAAA
GCACGGACACGTCAAAAAGGCGGTTTTGGTCTAGGATTGTCACTTGCTAAGCAAATTGTTGATGTTTTAAAAGGCGATAT
TCAAGTCAAAGATAACCAACCAAAAGGAACTATTTTTGAAGTTCGTTTTAATCGTCATTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(227-292)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(336-443)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.142

99.327

0.587
  ciaH Streptococcus pneumoniae Rx1

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae D39

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae R6

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae TIGR4

51.467

99.327

0.511

Multiple sequence alignment