Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   HMPREF9319_RS01250 Genome accession   NZ_GL397128
Coordinates   249416..250171 (+) Length   251 a.a.
NCBI ID   WP_003063294.1    Uniprot ID   -
Organism   Streptococcus equinus ATCC 700338     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 244416..255171
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9319_RS01235 (HMPREF9319_0242) - 244825..246396 (-) 1572 WP_003063286.1 ABC transporter permease subunit -
  HMPREF9319_RS01240 (HMPREF9319_0243) - 246529..248424 (+) 1896 WP_003063289.1 DUF2207 domain-containing protein -
  HMPREF9319_RS01245 (HMPREF9319_0244) - 248476..249315 (+) 840 WP_003063292.1 undecaprenyl-diphosphate phosphatase -
  HMPREF9319_RS01250 (HMPREF9319_0245) mecA 249416..250171 (+) 756 WP_003063294.1 adaptor protein MecA Regulator
  HMPREF9319_RS01255 (HMPREF9319_0246) - 250173..251336 (+) 1164 WP_003063296.1 glycosyltransferase family 4 protein -
  HMPREF9319_RS01260 (HMPREF9319_0247) sufC 251450..252220 (+) 771 WP_003063299.1 Fe-S cluster assembly ATPase SufC -
  HMPREF9319_RS01265 (HMPREF9319_0248) sufD 252294..253556 (+) 1263 WP_013851460.1 Fe-S cluster assembly protein SufD -
  HMPREF9319_RS01270 (HMPREF9319_0249) - 253558..254790 (+) 1233 WP_003063302.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 28931.69 Da        Isoelectric Point: 4.0627

>NTDB_id=1111669 HMPREF9319_RS01250 WP_003063294.1 249416..250171(+) (mecA) [Streptococcus equinus ATCC 700338]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRIDVFVTKSEI
NKEINFEDLAAFDDVSNMSPEEFFKTLEQTMLSKGDTEAHEKLGKIEEMMESAVEEVLTEQAQTEPSEDDINPSDYVHYV
FDFQTLEAVVAFAKAIDFPVEASELYKDGGLYHMTILLDLQNHPSYYANLMYARLLEYASTGTKTRAYLQEHGLEMLADD
AVVKLKMIELV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=1111669 HMPREF9319_RS01250 WP_003063294.1 249416..250171(+) (mecA) [Streptococcus equinus ATCC 700338]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTGGAAGAACGTGGCATGGAGTT
GAAAGATTTTTTGATTCCACAAGAAAAGACAGAGGAGTTCTTCTACTCAGTAATGGACGAATTAGATTTACCAGATAATT
TCAAAGATAGCGGAATGCTTAGTTTCCGTGTGACACCAAGAAAAGACCGTATTGATGTCTTTGTTACAAAATCTGAAATT
AATAAAGAAATTAATTTTGAAGATTTAGCTGCATTTGACGACGTGTCAAACATGTCACCTGAGGAATTTTTCAAAACATT
GGAACAAACAATGCTTTCTAAAGGTGATACTGAAGCGCATGAAAAATTAGGAAAAATTGAAGAAATGATGGAAAGTGCTG
TTGAGGAGGTTCTCACAGAACAAGCTCAAACAGAACCATCAGAAGATGACATTAATCCATCTGACTATGTTCATTATGTC
TTTGATTTTCAAACGCTTGAAGCTGTAGTAGCCTTTGCTAAAGCAATTGATTTTCCGGTTGAAGCATCAGAACTCTACAA
AGATGGTGGTCTTTACCACATGACCATTTTACTTGATTTACAAAATCATCCGTCATACTATGCGAATTTGATGTATGCTC
GTTTGTTGGAATATGCTAGCACAGGTACAAAAACGCGTGCTTATTTGCAAGAGCACGGTCTTGAAATGTTAGCAGATGAC
GCTGTTGTAAAATTAAAAATGATTGAGTTGGTATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

66.532

98.805

0.657
  mecA Streptococcus thermophilus LMD-9

59.919

98.406

0.59
  mecA Streptococcus thermophilus LMG 18311

59.514

98.406

0.586
  mecA Streptococcus pneumoniae Rx1

48.221

100

0.486
  mecA Streptococcus pneumoniae D39

48.221

100

0.486
  mecA Streptococcus pneumoniae R6

48.221

100

0.486
  mecA Streptococcus pneumoniae TIGR4

48.221

100

0.486

Multiple sequence alignment