Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   ACN076_RS03540 Genome accession   NZ_CP184836
Coordinates   715565..717466 (+) Length   633 a.a.
NCBI ID   WP_420790137.1    Uniprot ID   -
Organism   Streptococcus sp. K0074     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 710565..722466
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACN076_RS03525 (ACN076_03525) fmt 712572..713507 (+) 936 WP_420790134.1 methionyl-tRNA formyltransferase -
  ACN076_RS03530 (ACN076_03530) rsmB 713500..714813 (+) 1314 WP_420790135.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ACN076_RS03535 (ACN076_03535) - 714828..715568 (+) 741 WP_420790136.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACN076_RS03540 (ACN076_03540) stkP 715565..717466 (+) 1902 WP_420790137.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ACN076_RS03545 (ACN076_03545) - 717555..718313 (+) 759 WP_153226634.1 threonine/serine exporter family protein -
  ACN076_RS03550 (ACN076_03550) - 718315..718764 (+) 450 WP_125443542.1 threonine/serine exporter family protein -
  ACN076_RS03555 (ACN076_03555) - 718878..720050 (+) 1173 WP_185756862.1 hydroxymethylglutaryl-CoA synthase -
  ACN076_RS03560 (ACN076_03560) - 720050..721324 (+) 1275 WP_203175985.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 69202.55 Da        Isoelectric Point: 9.4667

>NTDB_id=1111444 ACN076_RS03540 WP_420790137.1 715565..717466(+) (stkP) [Streptococcus sp. K0074]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSSLSYNRRNEPKLVFNDTTKADTKTLPKVSQSTLTSIPKVQTQSPKPQTA
KPSQQVSEDNYATKSVKKRKFRVRYMILLASIVLVAASLIWILSRTPATIAIPDVAGQTVAEAKETLKKANFEIGEEKSE
ASEKVEEGRIIRTDPEAGKTRKEGSKINLVVSSGKQSFQLSNYIGRKSTDVIAELKQKKVPENLIKIEEEESSESEAGTV
LRQSPAAGTTYDLSKASTITLTVAKKVTSVSMPSYKGSSLEFTKNNLIQIVGIKEANIEVVEVSTAPDGTAEGTVVEQSP
KAGEKVDLTKTRVKISIYKPKTPPSTSSSAPSQRGNQGSTTTPSQGNQQGNQRGNAATTTQSSSEDNHENSRD

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=1111444 ACN076_RS03540 WP_420790137.1 715565..717466(+) (stkP) [Streptococcus sp. K0074]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTGAAACAGATTGGCCGAGGAGGCATGGCGGATGTCTA
TTTGGCCAAGGATTTAATTCTAGACGGAGAAGAAGTGGCAGTAAAGGTCCTGAGGACCAACTACCAGACGGACCCGATAG
CTGTAGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATCTAGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTATCTTGCAATGGAGTATGTTGCTGGACTAGACCTTAAACGCTATATCAAGGAACACTATCC
TCTCTCTAATGAAGAAGCGGTCCGTATTATGGGACAAATCCTCCTAGCCATGCGTTTGGCCCATACCAGAGGAATTGTTC
ACCGGGACTTGAAACCTCAAAATATCCTCTTGACACCAGATGGGACTGCCAAGGTCACAGACTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGTCTGACTCAGACTAACTCTATGTTGGGCTCAGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
GAAGGCGACTGTACAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGCTGACAGGCCATATCCCTTATGACG
GGGATAGCGCGGTGACCATCGCCCTTCAGCATTTCCAGAAACCACTGCCATCGGTTATAGCTGAAAATCCATCTGTGCCT
CAGGCTTTGGAGAATGTTGTTATCAAGGCAACTGCCAAGAAATTGACAGATCGTTATCAGTCAGTTGCAGAGATGTATGT
GGACTTGTCTAGTAGCTTGTCTTACAATCGTCGCAATGAGCCTAAACTGGTATTTAATGATACTACTAAGGCGGATACCA
AGACACTACCAAAGGTATCTCAGAGTACCTTGACTTCGATTCCTAAGGTGCAAACACAAAGTCCGAAGCCACAGACTGCG
AAGCCGAGTCAGCAGGTTTCAGAAGACAATTACGCAACCAAGTCTGTTAAGAAACGGAAATTTAGAGTTCGTTATATGAT
TTTGTTGGCCAGCATTGTATTGGTGGCAGCTTCTCTTATTTGGATCTTATCCAGAACTCCTGCAACCATTGCCATCCCAG
ATGTGGCAGGTCAGACAGTTGCGGAGGCCAAGGAAACGCTCAAGAAAGCCAATTTTGAGATTGGCGAGGAGAAATCAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGAAGCTGGAAAGACTCGAAAAGAAGGTTCGAAAAT
CAATTTGGTTGTCTCATCAGGCAAGCAATCTTTCCAATTGAGTAACTATATCGGCCGTAAATCGACAGATGTTATAGCAG
AACTCAAGCAGAAGAAGGTTCCTGAAAATCTCATCAAGATTGAGGAAGAAGAATCAAGTGAGAGCGAAGCAGGAACTGTT
CTCAGACAGAGTCCAGCTGCTGGAACAACCTATGATTTGAGCAAGGCCTCAACGATTACCTTAACCGTTGCTAAGAAAGT
AACCAGCGTTTCTATGCCAAGTTATAAAGGATCTAGTCTTGAATTTACTAAAAATAATCTTATTCAAATTGTTGGGATTA
AGGAAGCCAATATTGAAGTTGTAGAAGTGTCGACAGCTCCTGATGGAACTGCTGAGGGTACAGTCGTTGAACAGAGTCCA
AAAGCGGGTGAAAAGGTTGATTTGACTAAGACGCGTGTCAAGATTTCAATCTACAAACCAAAAACACCACCGTCAACGTC
ATCATCAGCACCATCCCAACGTGGAAACCAAGGTTCTACTACGACACCAAGTCAGGGGAACCAACAAGGAAATCAACGAG
GGAATGCAGCTACTACGACTCAATCAAGCAGTGAAGACAACCACGAAAATTCTCGTGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(371-432)

PASTA domain (PASTA)

(441-505)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

79.5

94.787

0.754
  stkP Streptococcus pneumoniae D39

79.167

94.787

0.75
  stkP Streptococcus pneumoniae R6

79.167

94.787

0.75
  stkP Streptococcus pneumoniae Rx1

79

94.787

0.749
  pknB Streptococcus mutans UA159

55.268

91.469

0.506
  stkP/pknB Streptococcus salivarius strain HSISS4

54.467

91.943

0.501

Multiple sequence alignment