Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   ACNR93_RS02395 Genome accession   NZ_CP184736
Coordinates   458053..459927 (+) Length   624 a.a.
NCBI ID   WP_420543810.1    Uniprot ID   -
Organism   Streptococcus equinus strain NM-2-29     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 453053..464927
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNR93_RS02380 (ACNR93_02380) fmt 455031..455966 (+) 936 WP_024344647.1 methionyl-tRNA formyltransferase -
  ACNR93_RS02385 (ACNR93_02385) rsmB 455956..457278 (+) 1323 WP_420543809.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ACNR93_RS02390 (ACNR93_02390) - 457316..458053 (+) 738 WP_024344649.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACNR93_RS02395 (ACNR93_02395) pknB 458053..459927 (+) 1875 WP_420543810.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ACNR93_RS02400 (ACNR93_02400) liaF 460071..460766 (+) 696 WP_420543811.1 cell wall-active antibiotics response protein LiaF -
  ACNR93_RS02405 (ACNR93_02405) - 460763..461788 (+) 1026 WP_021141792.1 sensor histidine kinase -
  ACNR93_RS02410 (ACNR93_02410) - 461772..462416 (+) 645 WP_024344653.1 response regulator transcription factor -
  ACNR93_RS02415 (ACNR93_02415) - 462540..463940 (+) 1401 WP_029876003.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ACNR93_RS02420 (ACNR93_02420) - 463940..464296 (+) 357 WP_027968108.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 68207.96 Da        Isoelectric Point: 5.2471

>NTDB_id=1110936 ACNR93_RS02395 WP_420543810.1 458053..459927(+) (pknB) [Streptococcus equinus strain NM-2-29]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSRERKLVFEDTENTKTLPKVTTSTPVPSTTEQLLKKQKAAKEN
KEVANQKAPKAKTKKKKSHRMFGTLMKIFFAVVVVAIAIFTYLTLSTPASVNVPDVSGAALSDAKTSLLSSGLKIGDIHK
VSSDTVAEGYVVKTDPTAGSSKKEGAKVDIYVSKGSSEFKMKDYTGQNYQDVIKELEKKHDISSKMIDIEWVTDTSYDSG
TIISQTPEEGTKVGDKDKITFEVAAITMPSLIGYTYQEAIAELNSMGVSSSHITIYMADATSSTGYSRVNSVSSSAVVVA
QDPYYGGAVEGEVNLYFSSETAAQPSEEPSQSVPESSETSETSESSSSSSSTEESSEASTEMQQ

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=1110936 ACNR93_RS02395 WP_420543810.1 458053..459927(+) (pknB) [Streptococcus equinus strain NM-2-29]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGTATCCTTAAATCAATCGGACGGGGTGGAATGGCAGATGTTTA
TCTTGCCAAAGATCTAATTCTTGATAATGAAGAAGTGGCTATCAAAGTCCTTCGAACTAATTATCAAACAGATCAAATTG
CCGTTGCTCGTTTCCAACGTGAAGCGCGTGCCATGGCAGAGCTAAACCATCCAAATATCGTTTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
TCTATCTAATAACGAAGTTGTTAGAATTATGGAAGAAGTCTTGTCAGCAATGACTCTTGCCCATCAACAAGGAATTGTTC
ACCGTGACTTAAAACCACAAAATATTTTGTTGACTAAAGACGGAACTGTAAAAGTTACTGACTTTGGTATTGCTGTAGCT
TTTGCAGAAACAAGTTTAACACAGACAAACTCAATGCTTGGTAGTGTGCATTATTTGTCACCTGAACAAGCGCGCGGTTC
AAAAGCCACTGTTCAAAGTGATATCTATGCTATGGGGATTATGTTGTTTGAAATGTTAACTGGACACATTCCTTATGATG
GTGACTCAGCTGTTACCATTGCACTTCAACATTTCCAAAAACCACTTCCATCAATCATTGATGAAAACAAAAATGTTCCT
CAAGCTTTGGAAAATGTAGTTATCAAAGCAACAGCAAAACGTTTAAGCGACCGTTATGCATCAACGTTTGAAATGAGTCG
TGATTTGATGACGGCACTTTCATACAACCGTAGTCGAGAACGTAAACTTGTTTTTGAGGATACAGAAAATACTAAGACAC
TTCCAAAAGTGACTACTTCAACACCTGTTCCATCAACGACAGAACAATTGTTGAAAAAACAAAAAGCTGCAAAAGAAAAT
AAAGAAGTAGCTAATCAAAAAGCACCTAAAGCGAAGACTAAAAAGAAAAAATCTCATCGTATGTTTGGTACTTTGATGAA
AATCTTCTTTGCAGTTGTTGTTGTTGCGATTGCTATCTTTACTTACTTAACTTTAAGTACACCAGCTTCAGTTAATGTTC
CAGATGTATCTGGTGCGGCTTTATCTGATGCTAAGACAAGCTTGTTATCATCTGGTTTGAAGATTGGTGATATCCACAAA
GTTTCTAGTGATACAGTTGCTGAAGGTTACGTTGTTAAAACAGATCCGACTGCTGGTTCATCTAAGAAAGAAGGAGCTAA
AGTTGATATTTATGTATCAAAAGGAAGTTCTGAATTCAAGATGAAAGATTACACTGGTCAAAATTATCAAGATGTCATCA
AGGAGCTTGAAAAGAAACATGATATTTCAAGTAAAATGATTGATATCGAGTGGGTAACTGATACTTCATATGATAGTGGT
ACTATTATCAGCCAAACTCCAGAAGAAGGAACAAAAGTTGGTGACAAAGATAAAATTACTTTTGAAGTAGCAGCAATCAC
AATGCCTAGTCTGATTGGTTATACTTACCAAGAAGCGATTGCTGAGTTAAATTCTATGGGTGTGTCAAGCTCACATATTA
CAATTTATATGGCAGATGCAACTTCATCAACAGGATACTCTCGAGTAAACTCAGTATCAAGTTCTGCGGTTGTCGTTGCT
CAGGATCCTTATTATGGTGGGGCTGTTGAAGGAGAGGTTAACCTTTACTTCTCTTCAGAAACGGCTGCGCAACCATCTGA
AGAACCGTCACAATCAGTTCCAGAATCATCTGAAACAAGTGAGACAAGTGAATCAAGTTCATCAAGTAGTAGTACTGAAG
AAAGTTCAGAAGCATCTACTGAAATGCAACAATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-247)

PASTA domain (PASTA)

(506-578)

PASTA domain (PASTA)

(440-503)

PASTA domain (PASTA)

(371-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

66.608

91.667

0.611
  stkP/pknB Streptococcus salivarius strain HSISS4

63.667

94.391

0.601
  stkP Streptococcus pneumoniae TIGR4

57.643

87.019

0.502
  stkP Streptococcus pneumoniae D39

57.459

87.019

0.5
  stkP Streptococcus pneumoniae R6

57.459

87.019

0.5
  stkP Streptococcus pneumoniae Rx1

57.274

87.019

0.498

Multiple sequence alignment