Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACNR93_RS01805 Genome accession   NZ_CP184736
Coordinates   338878..339639 (+) Length   253 a.a.
NCBI ID   WP_039691988.1    Uniprot ID   -
Organism   Streptococcus equinus strain NM-2-29     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 333878..344639
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNR93_RS01790 (ACNR93_01790) - 334284..335855 (-) 1572 WP_074567328.1 ABC transporter permease subunit -
  ACNR93_RS01795 (ACNR93_01795) - 335992..337884 (+) 1893 WP_420543766.1 DUF2207 family protein -
  ACNR93_RS01800 (ACNR93_01800) - 337936..338775 (+) 840 WP_003067592.1 undecaprenyl-diphosphate phosphatase -
  ACNR93_RS01805 (ACNR93_01805) mecA 338878..339639 (+) 762 WP_039691988.1 adaptor protein MecA Regulator
  ACNR93_RS01810 (ACNR93_01810) - 339641..340804 (+) 1164 WP_024344760.1 glycosyltransferase family 4 protein -
  ACNR93_RS01815 (ACNR93_01815) sufC 340926..341696 (+) 771 WP_003067585.1 Fe-S cluster assembly ATPase SufC -
  ACNR93_RS01820 (ACNR93_01820) sufD 341774..343036 (+) 1263 WP_074629241.1 Fe-S cluster assembly protein SufD -
  ACNR93_RS01825 (ACNR93_01825) - 343038..344270 (+) 1233 WP_420543767.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29055.86 Da        Isoelectric Point: 4.0441

>NTDB_id=1110930 ACNR93_RS01805 WP_039691988.1 338878..339639(+) (mecA) [Streptococcus equinus strain NM-2-29]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINFEDLAAFDDVSNMSPEEFFKTLEQTMMAKGDTEAHEKLGKIEEMMEGAVEEVLTEHAKQADTEPEEDVNPSDYVH
YVLDFPSLEATVAFSKAIDFPVEASELYKMDGAYYMTILLDLQNQPSYYANLMYARMLEYAGAGTKTRAYLQEHAVELLT
DDAVAKLKMIELV

Nucleotide


Download         Length: 762 bp        

>NTDB_id=1110930 ACNR93_RS01805 WP_039691988.1 338878..339639(+) (mecA) [Streptococcus equinus strain NM-2-29]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGAGGAATGGAGTT
AAAAGACTTTTTGATTCCGCAAGAAAAGACAGAAGAGTTCTTCTATTCAGTAATGGATGAGTTAGATTTACCAGATAATT
TCAAAGATAGCGGCATGCTTAGTTTTCGTGTGACACCACGTAAAGACCGTCTTGATGTATTTGTCACAAAATCAGAAATC
AACAAAGATATCAATTTTGAGGATTTAGCTGCGTTCGACGATGTGTCTAACATGTCACCAGAAGAATTCTTTAAAACGTT
AGAACAAACAATGATGGCTAAAGGTGACACTGAAGCTCATGAAAAATTAGGTAAAATCGAAGAAATGATGGAAGGTGCTG
TTGAAGAAGTCTTGACAGAGCACGCTAAGCAAGCAGATACAGAACCTGAAGAAGATGTAAACCCATCTGATTATGTTCAT
TACGTCTTAGATTTTCCAAGTTTAGAAGCAACAGTTGCTTTTTCTAAAGCGATTGATTTTCCTGTGGAAGCTTCTGAACT
TTACAAGATGGACGGCGCTTATTACATGACAATTTTGCTTGATTTGCAGAACCAACCTTCTTATTATGCAAATTTGATGT
ATGCCCGTATGTTAGAATACGCTGGCGCTGGTACAAAAACTCGTGCTTACTTACAAGAGCACGCAGTTGAACTATTGACG
GATGATGCCGTTGCAAAATTAAAAATGATTGAGTTGGTATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

66.4

98.814

0.656
  mecA Streptococcus thermophilus LMD-9

60.643

98.419

0.597
  mecA Streptococcus thermophilus LMG 18311

59.839

98.419

0.589
  mecA Streptococcus pneumoniae Rx1

49.02

100

0.494
  mecA Streptococcus pneumoniae D39

49.02

100

0.494
  mecA Streptococcus pneumoniae R6

49.02

100

0.494
  mecA Streptococcus pneumoniae TIGR4

49.02

100

0.494

Multiple sequence alignment