Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ACKTSL_RS01980 Genome accession   NZ_AP035890
Coordinates   383699..384946 (-) Length   415 a.a.
NCBI ID   WP_311897334.1    Uniprot ID   A0AAW8TLX3
Organism   Enterococcus cecorum strain SMUHEc01     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 378699..389946
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKTSL_RS01945 (SMUE_03590) - 378847..379158 (+) 312 WP_191465211.1 thioredoxin family protein -
  ACKTSL_RS01950 (SMUE_03600) - 379181..379624 (+) 444 WP_168930744.1 universal stress protein -
  ACKTSL_RS01955 (SMUE_03610) - 379666..380271 (+) 606 WP_248622378.1 CadD family cadmium resistance transporter -
  ACKTSL_RS01960 (SMUE_03620) ytpR 380350..380961 (+) 612 WP_047341800.1 YtpR family tRNA-binding protein -
  ACKTSL_RS01965 (SMUE_03630) - 381029..381199 (-) 171 WP_168930749.1 hypothetical protein -
  ACKTSL_RS01970 (SMUE_03640) - 381202..382431 (-) 1230 WP_311897332.1 MFS transporter -
  ACKTSL_RS01975 (SMUE_03660) - 382801..383457 (+) 657 WP_311897333.1 Crp/Fnr family transcriptional regulator -
  ACKTSL_RS01980 (SMUE_03670) htrA 383699..384946 (-) 1248 WP_311897334.1 trypsin-like peptidase domain-containing protein Regulator
  ACKTSL_RS01985 (SMUE_03680) rlmH 385404..385883 (+) 480 WP_248622446.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACKTSL_RS01990 (SMUE_03690) - 385891..386589 (+) 699 WP_171301608.1 hydrolase -
  ACKTSL_RS01995 (SMUE_03700) - 386737..387915 (+) 1179 WP_322379970.1 MalY/PatB family protein -
  ACKTSL_RS02000 (SMUE_03710) - 387942..389042 (+) 1101 WP_322379969.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
  ACKTSL_RS02005 (SMUE_03720) - 389045..389794 (+) 750 WP_243190950.1 NADPH-dependent oxidoreductase -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 43220.22 Da        Isoelectric Point: 6.0507

>NTDB_id=110914 ACKTSL_RS01980 WP_311897334.1 383699..384946(-) (htrA) [Enterococcus cecorum strain SMUHEc01]
MSRRKNSNTIMKRFGIGICSGVIGGALAFGGLYAVTGMNHTTSSTGIQSAQTATKVQNAKYNVESDVTKAVSKVQGAVVS
IINLQKQNAQGTGGLEDFFGAQQGNSSNQNSGTLETASEGSGVIYKKEGKHAYIVTNNHVVEGQNALQVLLADGTKVDAE
LVGTDSYTDLAVIKIASDKVSTVATFGDSDNLKVGEPAIAIGSPLGTDYANSVTEGIISSLNRQVVSENDSGQEVNINAI
QTDAAINPGNSGGPLINIAGQVIGINSSKIATTSTSSSGVSVEGMGFAIPSNDVVNIINQLEQSGKVTRPALGVRTVDLN
ALSDQQKTNILKVPTSLNEGVVLAQVNSATPAEKAGLKQYDVITEIDGKKVNDGTELRAALYKKHVGDSIKVTYYRGNDK
KTTTVHLTVDQSINE

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=110914 ACKTSL_RS01980 WP_311897334.1 383699..384946(-) (htrA) [Enterococcus cecorum strain SMUHEc01]
ATGAGTAGAAGAAAAAATTCAAATACAATTATGAAAAGATTTGGTATCGGCATTTGTAGCGGTGTGATTGGTGGTGCTCT
TGCTTTTGGCGGCTTGTATGCAGTCACTGGAATGAATCATACGACTAGTTCAACAGGTATTCAAAGTGCACAAACAGCAA
CTAAAGTTCAAAATGCGAAATATAATGTAGAAAGCGACGTAACAAAAGCGGTCTCTAAAGTACAAGGTGCAGTCGTTTCA
ATCATTAATTTACAAAAACAAAACGCACAAGGCACAGGCGGTTTAGAAGATTTCTTTGGTGCCCAACAAGGAAATAGTAG
CAATCAAAATAGCGGCACTTTGGAAACAGCCAGTGAAGGTAGTGGCGTCATTTATAAAAAAGAAGGTAAACATGCTTATA
TCGTGACAAATAATCACGTGGTTGAAGGTCAAAATGCATTACAAGTCTTACTAGCAGACGGTACCAAAGTCGATGCTGAA
TTAGTTGGTACGGACAGCTATACTGACTTAGCGGTAATCAAGATTGCTAGCGATAAAGTTTCAACGGTTGCTACTTTTGG
CGATTCAGATAATCTAAAAGTTGGTGAACCTGCCATCGCCATCGGATCACCATTAGGAACCGATTATGCCAACTCAGTGA
CTGAAGGAATTATTTCTTCTTTAAATCGTCAAGTCGTGAGTGAAAATGATTCCGGCCAAGAAGTTAATATCAACGCTATC
CAAACTGATGCAGCGATTAACCCTGGTAACTCTGGTGGTCCATTAATTAATATCGCCGGTCAAGTTATCGGAATTAACTC
AAGTAAAATTGCTACCACTTCAACCTCAAGCTCTGGTGTAAGTGTTGAAGGTATGGGCTTTGCAATTCCAAGTAATGATG
TCGTCAATATTATTAACCAACTAGAACAAAGTGGGAAAGTGACTCGTCCTGCTTTAGGGGTTAGAACGGTTGATTTGAAT
GCTTTATCTGATCAACAAAAAACGAACATCTTAAAAGTACCTACCTCATTAAATGAAGGGGTCGTGCTTGCTCAAGTCAA
CAGTGCAACGCCTGCAGAAAAAGCTGGCTTGAAACAATATGATGTCATTACTGAAATTGATGGTAAAAAGGTCAATGATG
GCACTGAATTAAGAGCCGCTCTTTATAAAAAACATGTCGGTGACAGCATTAAAGTGACTTACTATCGTGGCAATGACAAA
AAGACAACCACCGTACACCTTACCGTCGACCAATCAATTAATGAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(310-407)

Peptidase family M50 (Peptidase_M50)

(251-410)

Trypsin-like peptidase domain (Trypsin_2)

(120-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

55.989

86.506

0.484
  htrA Streptococcus gordonii str. Challis substr. CH1

48.894

98.072

0.48
  htrA Streptococcus pneumoniae R6

48.293

98.795

0.477
  htrA Streptococcus pneumoniae TIGR4

48.293

98.795

0.477
  htrA Streptococcus pneumoniae D39

48.293

98.795

0.477
  htrA Streptococcus pneumoniae Rx1

48.293

98.795

0.477
  htrA Streptococcus mitis NCTC 12261

49.869

92.289

0.46

Multiple sequence alignment