Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   ID09_RS00245 Genome accession   NZ_CP008921
Coordinates   37947..38846 (+) Length   299 a.a.
NCBI ID   WP_024382136.1    Uniprot ID   -
Organism   Streptococcus suis 6407     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 32947..43846
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ID09_RS00230 (ID09_00250) - 33714..35426 (+) 1713 WP_014917170.1 ABC transporter ATP-binding protein -
  ID09_RS12130 - 35528..35701 (+) 174 WP_014735240.1 hypothetical protein -
  ID09_RS00235 (ID09_00260) ruvB 35996..36997 (+) 1002 WP_024377694.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  ID09_RS00240 (ID09_00265) - 37065..37700 (+) 636 WP_024382137.1 HAD-IA family hydrolase -
  ID09_RS00245 (ID09_00270) comR 37947..38846 (+) 900 WP_024382136.1 helix-turn-helix domain-containing protein Regulator
  ID09_RS00250 (ID09_00275) - 39272..40460 (+) 1189 Protein_30 IS110 family transposase -
  ID09_RS00255 (ID09_00280) - 41135..42073 (-) 939 WP_024381983.1 IS4 family transposase -
  ID09_RS00260 (ID09_00285) - 42210..43430 (+) 1221 WP_024381982.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35425.29 Da        Isoelectric Point: 4.6492

>NTDB_id=110810 ID09_RS00245 WP_024382136.1 37947..38846(+) (comR) [Streptococcus suis 6407]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPISKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=110810 ID09_RS00245 WP_024382136.1 37947..38846(+) (comR) [Streptococcus suis 6407]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTACTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTACGTATCCTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTCTAAGGGATACATTATTATCCTGTG
TAAACATTTTGGGAAGTAAAAAATATTACGAACCAATATCAAAGATATTTGATAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAAAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterProScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

99.331

100

0.993
  comR Streptococcus suis 05ZYH33

99.331

100

0.993
  comR Streptococcus suis D9

61.462

100

0.619
  comR Streptococcus mutans UA159

43.813

100

0.438
  comR Streptococcus pyogenes MGAS315

37.374

99.331

0.371

Multiple sequence alignment