Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   V3C22_RS01285 Genome accession   NZ_CP183775
Coordinates   268794..269516 (+) Length   240 a.a.
NCBI ID   WP_226708967.1    Uniprot ID   -
Organism   Streptococcus mutans strain Xc     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 263794..274516
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V3C22_RS01270 (V3C22_01270) - 264194..265747 (-) 1554 WP_002280005.1 ABC transporter substrate-binding protein/permease -
  V3C22_RS01275 (V3C22_01275) - 265900..267801 (+) 1902 WP_019321894.1 DUF2207 domain-containing protein -
  V3C22_RS01280 (V3C22_01280) - 267859..268704 (+) 846 WP_002262750.1 undecaprenyl-diphosphate phosphatase -
  V3C22_RS01285 (V3C22_01285) mecA 268794..269516 (+) 723 WP_226708967.1 adaptor protein MecA Regulator
  V3C22_RS01290 (V3C22_01290) rgpG 269522..270682 (+) 1161 WP_002276222.1 rhamnose-glucose polysaccharide biosynthesis protein RgpB -
  V3C22_RS01295 (V3C22_01295) sufC 270756..271526 (+) 771 WP_002262747.1 Fe-S cluster assembly ATPase SufC -
  V3C22_RS01300 (V3C22_01300) sufD 271564..272826 (+) 1263 WP_002270785.1 Fe-S cluster assembly protein SufD -
  V3C22_RS01305 (V3C22_01305) - 272831..274060 (+) 1230 WP_002301853.1 cysteine desulfurase -
  V3C22_RS01310 (V3C22_01310) sufU 274047..274481 (+) 435 WP_002262744.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27970.59 Da        Isoelectric Point: 4.2574

>NTDB_id=1105920 V3C22_RS01285 WP_226708967.1 268794..269516(+) (mecA) [Streptococcus mutans strain Xc]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKGSGMLSFRVTPRNDRIDVFVTKSEI
NKNLNLEDLSDFDDISKMSPEDFFNTLEETMREKGDAAALDKLAEIEKREEEKTQQEKGETKEKRDYVHFVLDFPNIQQV
ISFAKTVDYDVEASELFKESDAYHMTVLLNLEDKPDYYADLMFARMLEHAGRGTKTRAYLLEHGVQLIKADALQELQMIG

Nucleotide


Download         Length: 723 bp        

>NTDB_id=1105920 V3C22_RS01285 WP_226708967.1 268794..269516(+) (mecA) [Streptococcus mutans strain Xc]
ATGGAAATGAAACAAATCAGCGAAACAACATTAAAAATCACCATCAGTATGGAAGATTTAGAAGAAAGAGGCATGGAATT
AAAAGATTTCTTGATTCCGCAGGAAAAGACGGAAGAATTTTTCTATACTGTTATGGATGAGCTGGACTTGCCTGAAAATT
TCAAGGGCAGTGGGATGTTAAGCTTTCGAGTAACACCAAGGAATGATCGCATTGATGTTTTTGTCACTAAGTCAGAAATC
AATAAAAATCTTAATTTGGAGGATTTGTCTGATTTTGATGATATTTCAAAAATGTCCCCGGAGGATTTCTTTAATACCTT
GGAGGAAACCATGCGTGAAAAAGGGGATGCTGCAGCTCTGGATAAATTGGCTGAAATTGAAAAAAGAGAAGAAGAGAAGA
CTCAGCAGGAAAAAGGTGAAACTAAGGAAAAAAGAGATTACGTTCACTTTGTGCTGGATTTTCCTAATATTCAGCAAGTC
ATAAGTTTTGCTAAGACAGTTGACTATGATGTAGAGGCTTCAGAACTTTTTAAGGAGTCTGACGCTTATCACATGACTGT
TCTGCTTAATCTCGAAGATAAACCTGACTATTATGCTGATCTTATGTTTGCAAGAATGTTGGAGCATGCTGGTAGAGGAA
CAAAGACACGTGCTTATCTATTAGAACATGGAGTTCAGCTCATTAAAGCAGATGCTCTGCAAGAATTACAAATGATTGGA
TAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

99.167

100

0.992
  mecA Streptococcus thermophilus LMD-9

57.787

100

0.588
  mecA Streptococcus thermophilus LMG 18311

57.377

100

0.583
  mecA Streptococcus pneumoniae Rx1

48.163

100

0.492
  mecA Streptococcus pneumoniae D39

48.163

100

0.492
  mecA Streptococcus pneumoniae R6

48.163

100

0.492
  mecA Streptococcus pneumoniae TIGR4

48.163

100

0.492

Multiple sequence alignment