Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ACM2W4_RS04680 Genome accession   NZ_CP181086
Coordinates   976210..977514 (-) Length   434 a.a.
NCBI ID   WP_010747716.1    Uniprot ID   A0A242C4H0
Organism   Enterococcus casseliflavus strain B6     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 971210..982514
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM2W4_RS04650 (ACM2W4_04650) - 971217..972251 (+) 1035 WP_005225424.1 hypothetical protein -
  ACM2W4_RS04655 (ACM2W4_04655) - 972312..972656 (-) 345 WP_005225425.1 peptidase -
  ACM2W4_RS04660 (ACM2W4_04660) pepA 972949..974025 (+) 1077 WP_005225427.1 glutamyl aminopeptidase -
  ACM2W4_RS04665 (ACM2W4_04665) - 974159..974479 (+) 321 WP_005225428.1 thioredoxin family protein -
  ACM2W4_RS04670 (ACM2W4_04670) - 974492..974953 (+) 462 WP_005225429.1 universal stress protein -
  ACM2W4_RS04675 (ACM2W4_04675) ytpR 975527..976141 (+) 615 WP_005225431.1 YtpR family tRNA-binding protein -
  ACM2W4_RS04680 (ACM2W4_04680) htrA 976210..977514 (-) 1305 WP_010747716.1 S1C family serine protease Regulator
  ACM2W4_RS04685 (ACM2W4_04685) rlmH 977889..978368 (+) 480 WP_010747717.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACM2W4_RS04690 (ACM2W4_04690) truA 978434..979171 (+) 738 WP_005225435.1 tRNA pseudouridine(38-40) synthase TruA -
  ACM2W4_RS04695 (ACM2W4_04695) map 979214..979972 (+) 759 WP_005225436.1 type I methionyl aminopeptidase -
  ACM2W4_RS04700 (ACM2W4_04700) - 980542..981915 (+) 1374 WP_416135971.1 C40 family peptidase -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 44836.30 Da        Isoelectric Point: 4.0084

>NTDB_id=1098078 ACM2W4_RS04680 WP_010747716.1 976210..977514(-) (htrA) [Enterococcus casseliflavus strain B6]
MARKYVTPGKKTSPGLLKRLGIGILGGMVGGLLTFGGLYLAMGSSLTSTPETTTNSGVQDSNGQTQVSNVKLDVTSDVTE
AVEKVQDSVVSIINLQQSQSNDWNSLFGQQGGQSEGDSQSDDDSALEASSEGSGVIYKIDGDDAYVVTNNHVVEGQDGLE
VVLADGTKVKAELVGTDAYTDLAVLKISSEHVTTAATFGDSSALKVGEPAIAIGSPLGSDYANSVTQGIVSSLNRQVTSQ
NESGGTISINAIQTDAAINPGNSGGPLINVDGQVIGINSSKIASTSGSASGVSVEGMGFAIPSNDVVEIINQLEADGKVV
RPALGIQTIDLGSITSQQQEQILKVPSSVTSGVVIYSVNNATPAEQAGLQQYDVITKIDDTEVSTTTDLQSALYKHKVGD
TITVTFYRGDEEKTAEVKLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=1098078 ACM2W4_RS04680 WP_010747716.1 976210..977514(-) (htrA) [Enterococcus casseliflavus strain B6]
ATGGCAAGAAAATATGTCACACCAGGCAAGAAAACTTCTCCTGGTTTATTAAAACGATTAGGTATTGGGATTTTAGGCGG
TATGGTCGGCGGTTTATTGACCTTCGGCGGTCTGTATCTGGCAATGGGTTCCTCTTTGACTTCAACACCAGAAACCACGA
CCAACAGCGGGGTCCAAGATTCTAACGGACAAACCCAAGTATCCAATGTAAAACTTGATGTGACTAGCGATGTCACTGAG
GCAGTTGAAAAAGTACAAGATTCTGTCGTTTCCATCATTAATCTACAACAAAGTCAAAGCAACGACTGGAACAGCCTCTT
TGGTCAGCAAGGCGGACAAAGTGAAGGCGATAGCCAAAGCGACGACGACAGTGCTTTAGAAGCTTCTTCTGAAGGGAGTG
GAGTCATCTACAAAATCGATGGCGACGATGCCTATGTTGTAACCAACAACCACGTCGTAGAAGGTCAAGACGGTTTGGAA
GTTGTTTTAGCAGACGGTACGAAAGTTAAAGCTGAATTGGTCGGTACTGACGCTTACACAGACTTAGCTGTATTGAAAAT
CTCTTCAGAGCATGTGACGACTGCCGCAACATTTGGTGATTCAAGTGCCTTGAAAGTCGGCGAACCAGCCATCGCGATCG
GTTCACCTCTCGGCTCTGACTACGCAAACTCTGTGACACAAGGGATCGTTTCTTCCTTGAATCGTCAAGTAACAAGCCAA
AACGAATCTGGTGGTACGATCAGCATCAATGCGATCCAAACGGATGCTGCGATCAACCCAGGGAACTCTGGTGGTCCACT
GATCAACGTTGATGGTCAAGTGATTGGGATCAACTCAAGTAAAATCGCCAGCACCTCTGGCTCTGCTTCAGGTGTTAGTG
TCGAAGGGATGGGCTTTGCGATCCCAAGTAACGATGTCGTTGAAATCATCAATCAACTAGAAGCAGACGGCAAAGTGGTC
CGCCCTGCACTAGGTATCCAAACGATCGATTTAGGTTCCATCACATCACAACAACAAGAACAAATCTTGAAAGTTCCTTC
ATCCGTAACTTCAGGCGTTGTGATCTATTCAGTCAACAATGCAACACCAGCAGAACAAGCAGGATTGCAACAATATGATG
TTATCACGAAGATCGATGATACAGAAGTCAGCACAACAACGGATCTACAATCTGCGTTGTACAAACACAAAGTCGGTGAC
ACGATCACTGTAACCTTCTATCGTGGCGATGAAGAAAAAACGGCAGAAGTAAAACTTTCCGTTGATACATCGATCAACGA
ACAATCAACAGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(19-420)

Trypsin-like peptidase domain (Trypsin_2)

(132-277)

PDZ domain (PDZ_2)

(322-419)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A242C4H0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.423

91.475

0.516
  htrA Streptococcus gordonii str. Challis substr. CH1

50.835

96.544

0.491
  htrA Streptococcus mitis NCTC 12261

55.71

82.719

0.461
  htrA Streptococcus pneumoniae TIGR4

57.31

78.802

0.452
  htrA Streptococcus pneumoniae D39

57.31

78.802

0.452
  htrA Streptococcus pneumoniae Rx1

57.31

78.802

0.452
  htrA Streptococcus pneumoniae R6

57.31

78.802

0.452

Multiple sequence alignment