Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ABXG87_RS04115 Genome accession   NZ_AP031488
Coordinates   913217..914632 (+) Length   471 a.a.
NCBI ID   WP_004182392.1    Uniprot ID   A0AB33ZDN7
Organism   Streptococcus salivarius strain NBRC 13956     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 908217..919632
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABXG87_RS04090 (Ssa13956_07500) - 908668..909240 (-) 573 WP_353551988.1 ECF transporter S component -
  ABXG87_RS04095 (Ssa13956_07510) coaC 909269..909814 (-) 546 WP_084871335.1 phosphopantothenoylcysteine decarboxylase -
  ABXG87_RS04100 (Ssa13956_07520) - 909807..910490 (-) 684 WP_084871336.1 phosphopantothenate--cysteine ligase -
  ABXG87_RS04105 (Ssa13956_07530) - 910684..912354 (+) 1671 WP_084871337.1 formate--tetrahydrofolate ligase -
  ABXG87_RS04110 (Ssa13956_07540) ciaR 912553..913227 (+) 675 WP_049546057.1 response regulator transcription factor Regulator
  ABXG87_RS04115 (Ssa13956_07550) ciaH 913217..914632 (+) 1416 WP_004182392.1 HAMP domain-containing sensor histidine kinase Regulator
  ABXG87_RS04120 (Ssa13956_07560) rpsT 914710..914946 (-) 237 WP_004182129.1 30S ribosomal protein S20 -
  ABXG87_RS04125 (Ssa13956_07570) coaA 915016..915936 (-) 921 WP_004182393.1 type I pantothenate kinase -
  ABXG87_RS04130 (Ssa13956_07580) - 916049..916639 (+) 591 WP_004182394.1 class I SAM-dependent methyltransferase -
  ABXG87_RS04135 (Ssa13956_07590) - 916636..917913 (+) 1278 WP_004182395.1 pyrimidine-nucleoside phosphorylase -
  ABXG87_RS04140 (Ssa13956_07600) deoC 917947..918609 (+) 663 WP_004182396.1 deoxyribose-phosphate aldolase -
  ABXG87_RS04145 (Ssa13956_07610) - 918596..918994 (+) 399 WP_004182397.1 cytidine deaminase -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53504.28 Da        Isoelectric Point: 8.7661

>NTDB_id=109794 ABXG87_RS04115 WP_004182392.1 913217..914632(+) (ciaH) [Streptococcus salivarius strain NBRC 13956]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKESTAETPDSSGSKKEPKKKSKIEDTPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVGRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=109794 ABXG87_RS04115 WP_004182392.1 913217..914632(+) (ciaH) [Streptococcus salivarius strain NBRC 13956]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTGCAGATTCTGAGTTACGGCGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCCACTAAAACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAAAGAGTCGACAGCTGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAACCTAAGAAGAAATCAAAAATTGAAGATACCCCTCACGATTTATCTGTTGCGGCAAATACTAGTGTCT
TGGTACTTGATAAGAATGGAAAAGTCCTTAATGTCGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGACAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTACCGTCTGATTACTGAAAAAGT
AGATAATAGCCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCCACTGAACGTT
ATGTTAAGCTAATTGTCATCATGATGAGTTTCTTCTGGCTTTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAGAATGCTAGCCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTCTAGATAATTCAGAGAATATTGCTTCAA
GTCTTGATGAAGTACGCAACATGCGTCTTTTGACGACTAATCTTTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAATCAAGTTGGTCGTCCAATCCAGACTGATAAAACGTTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGATGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGAATATCAGATAGTGATAAGAAAAAAATCTTTGATCGCTTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCTCTAGCGCAACAAATTGTTTTAGCCCTAAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATCACCGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.739

97.665

0.554
  ciaH Streptococcus pneumoniae Rx1

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae D39

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae R6

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.216

98.514

0.495

Multiple sequence alignment