Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ABXG87_RS01580 Genome accession   NZ_AP031488
Coordinates   296956..297645 (+) Length   229 a.a.
NCBI ID   WP_002886589.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NBRC 13956     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 291956..302645
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABXG87_RS01555 (Ssa13956_02540) - 292186..293016 (+) 831 WP_002886584.1 energy-coupling factor transporter transmembrane component T -
  ABXG87_RS01560 (Ssa13956_02550) - 293105..293776 (-) 672 WP_014633599.1 TrkA family potassium uptake protein -
  ABXG87_RS01565 (Ssa13956_02560) - 293816..295180 (-) 1365 WP_081370834.1 potassium transporter TrkG -
  ABXG87_RS01570 (Ssa13956_02570) rsmG 295249..295965 (-) 717 WP_214252773.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  ABXG87_RS01575 (Ssa13956_02580) - 296264..296800 (+) 537 WP_353551702.1 YceD family protein -
  ABXG87_RS01580 (Ssa13956_02590) covR 296956..297645 (+) 690 WP_002886589.1 response regulator transcription factor Regulator
  ABXG87_RS01585 (Ssa13956_02600) covS 297642..299171 (+) 1530 WP_353551704.1 HAMP domain-containing histidine kinase Regulator
  ABXG87_RS01590 (Ssa13956_02610) nrdR 299293..299772 (+) 480 WP_002886592.1 transcriptional regulator NrdR -
  ABXG87_RS01595 (Ssa13956_02620) - 299769..300944 (+) 1176 WP_049529055.1 DnaD domain protein -
  ABXG87_RS01600 (Ssa13956_02630) dnaI 300948..301850 (+) 903 WP_002883792.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26517.51 Da        Isoelectric Point: 4.6354

>NTDB_id=109774 ABXG87_RS01580 WP_002886589.1 296956..297645(+) (covR) [Streptococcus salivarius strain NBRC 13956]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIESAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=109774 ABXG87_RS01580 WP_002886589.1 296956..297645(+) (covR) [Streptococcus salivarius strain NBRC 13956]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAATCTGCTAAGAATGCACCAGCAAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTGGTAGATGTTTATATTCGTTATTTGCGTGGAAAAATCGACGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

99.563

100

0.996
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

46.352

100

0.472
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445

Multiple sequence alignment