Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   ABXG87_RS01585 Genome accession   NZ_AP031488
Coordinates   297642..299171 (+) Length   509 a.a.
NCBI ID   WP_353551704.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NBRC 13956     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 292642..304171
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABXG87_RS01560 (Ssa13956_02550) - 293105..293776 (-) 672 WP_014633599.1 TrkA family potassium uptake protein -
  ABXG87_RS01565 (Ssa13956_02560) - 293816..295180 (-) 1365 WP_081370834.1 potassium transporter TrkG -
  ABXG87_RS01570 (Ssa13956_02570) rsmG 295249..295965 (-) 717 WP_214252773.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  ABXG87_RS01575 (Ssa13956_02580) - 296264..296800 (+) 537 WP_353551702.1 YceD family protein -
  ABXG87_RS01580 (Ssa13956_02590) covR 296956..297645 (+) 690 WP_002886589.1 response regulator transcription factor Regulator
  ABXG87_RS01585 (Ssa13956_02600) covS 297642..299171 (+) 1530 WP_353551704.1 HAMP domain-containing histidine kinase Regulator
  ABXG87_RS01590 (Ssa13956_02610) nrdR 299293..299772 (+) 480 WP_002886592.1 transcriptional regulator NrdR -
  ABXG87_RS01595 (Ssa13956_02620) - 299769..300944 (+) 1176 WP_049529055.1 DnaD domain protein -
  ABXG87_RS01600 (Ssa13956_02630) dnaI 300948..301850 (+) 903 WP_002883792.1 primosomal protein DnaI -
  ABXG87_RS01605 (Ssa13956_02640) der 301955..303265 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  ABXG87_RS01610 (Ssa13956_02650) - 303330..303959 (+) 630 WP_049529052.1 hypothetical protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58136.59 Da        Isoelectric Point: 5.5274

>NTDB_id=109775 ABXG87_RS01585 WP_353551704.1 297642..299171(+) (covS) [Streptococcus salivarius strain NBRC 13956]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSLFTLVVIFSANTLLLQRERQNVNTTIAKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLVFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERLAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALENEMLVQVQDNGEGISKEDINHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADRETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=109775 ABXG87_RS01585 WP_353551704.1 297642..299171(+) (covS) [Streptococcus salivarius strain NBRC 13956]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGTTGTTCACTCTGGTTGTTATTTTTTCAGCTAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCGCAAAAGTTGTTACTTACATCGAAAAGGATTGGGATTCGGATGAAGAATTAAGTCCAGAACCGCTCTTA
GCGGCTCTTTATTCGCCTAAAAATATCTATGCATCAATTATTAATGGCGTACTTTCTGAAAAGCACTCTTTGGATGGTCA
AGTTGCAATTTCTAATAAATTATATTCAAATCAGTCAGTTTTTGTGTATGACAAAAAAGGAACCTTTATCTTTACTTCTG
AGGAGAATACAGATTCGCCTCCCGGTATGTCCGAGGTAAACAAACTGAAGTCAGTATCCTATAAAGGAAAGCGTGGTTTC
TTACTACAAGTTCCAATTTACGGTAAGGATAAAAAGACCATCGTTGGCTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTTAAAGAGCGTTTGGTTTTCTTGTTGATTTTCCTAGAAGTGGGGATGACTGTCCTAGTTATCGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATTACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGCATGATGGATAAAAT
TCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTACGTACGCCGATTGCAGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAAGAAAGTCTTGAGGCTGCCAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCATAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGGAACTTCCGTGTCTTGCATGAAGACTATCAATTTTATCTCA
ATGATTTCGAAAGTTCAGAGCGTCTAGCACAGATTTATAGTCAGCACTTTGAACAGGCTATCACCATTTTGATTGATAAT
GCGGTCAAGTATTCGCCTGTCAATAAGGAAATACAGGTTACTATTAAAGCATTGGAAAATGAAATGTTGGTACAAGTGCA
AGATAACGGTGAGGGGATTTCAAAAGAAGATATCAATCATATTTTTGAACGTTTCTATCGTTCAGATAAGGCGCGTAACC
GTACAACAACTCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTATCAAATTGTGGAAGCTTATCGCTGCCGTATTGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATCGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

HAMP domain (HAMP)

(217-269)

ArlS sensor domain (ArlS_N)

(43-191)

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

98.428

100

0.984

Multiple sequence alignment