Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   ACM3H0_RS02395 Genome accession   NZ_CP180685
Coordinates   416066..416746 (+) Length   226 a.a.
NCBI ID   WP_057990271.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain M14     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 411066..421746
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM3H0_RS02380 (ACM3H0_02380) pstB 411764..412522 (+) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -
  ACM3H0_RS02385 (ACM3H0_02385) phoU 412556..413209 (+) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  ACM3H0_RS02390 (ACM3H0_02390) - 413355..415904 (+) 2550 WP_000859383.1 M1 family metallopeptidase -
  ACM3H0_RS02395 (ACM3H0_02395) ciaR 416066..416746 (+) 681 WP_057990271.1 response regulator transcription factor Regulator
  ACM3H0_RS02400 (ACM3H0_02400) ciaH 416730..418043 (+) 1314 WP_000042576.1 sensor histidine kinase Regulator
  ACM3H0_RS02405 (ACM3H0_02405) - 418132..418464 (+) 333 WP_000402075.1 putative DNA-binding protein -
  ACM3H0_RS02410 (ACM3H0_02410) ffh 418482..420047 (+) 1566 WP_000863589.1 signal recognition particle protein -
  ACM3H0_RS02415 (ACM3H0_02415) - 420114..420800 (+) 687 WP_000280305.1 SatD family protein -
  ACM3H0_RS02420 (ACM3H0_02420) - 420790..421563 (+) 774 WP_000622398.1 DUF3307 domain-containing protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 25851.64 Da        Isoelectric Point: 4.2854

>NTDB_id=1097392 ACM3H0_RS02395 WP_057990271.1 416066..416746(+) (ciaR) [Streptococcus agalactiae strain M14]
MIKILLIEDDLSLSNSVFNFLDDFADVMQIFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KESIDDKGQGFDLGADDYLTKPFYLEELKMRIQALLKRSGKFNDNSLIYGDIRVDMSTNSTFVNQTEVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTLFSENLQTLRSVGYILKHVETD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=1097392 ACM3H0_RS02395 WP_057990271.1 416066..416746(+) (ciaR) [Streptococcus agalactiae strain M14]
ATGATAAAAATTTTATTAATTGAAGATGACTTGAGTCTTTCCAATTCCGTTTTTAATTTCCTTGATGACTTTGCCGATGT
CATGCAAATTTTTGATGGAGAAGAGGGTCTTTACGAAGCCGAAAGTGGAGTCTATGATCTGATTCTTCTAGATCTCATGT
TACCTGAAAAAAACGGCTTCCAAGTGTTGAAAGAGCTACGTGAAAAAGGTATTACAACCCCTGTATTAATAATGACCGCT
AAAGAAAGCATTGATGATAAGGGACAAGGTTTCGACTTAGGTGCTGATGATTATCTAACAAAACCTTTTTACCTAGAAGA
ACTAAAAATGCGAATTCAGGCTCTTTTAAAGCGTTCTGGAAAATTTAATGATAACAGCCTAATTTATGGTGATATTCGCG
TAGACATGTCTACTAACTCAACCTTTGTTAATCAAACAGAAGTTGAGCTCTTAGGTAAAGAGTTTGATCTTTTAGTCTAT
TTCCTTCAAAATCAAAATGTTATCTTACCGAAATCTCAAATCTTTGATCGTATTTGGGGATTTGATAGTGATACAACGAT
TTCAGTTGTAGAAGTCTATGTCTCTAAGGTTCGGAAAAAATTAAAAGGAACACTTTTTTCAGAAAACCTTCAAACTTTGC
GTAGTGTAGGATATATTTTAAAGCATGTCGAAACCGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae TIGR4

87.946

99.115

0.872
  ciaR Streptococcus pneumoniae D39

87.946

99.115

0.872
  ciaR Streptococcus pneumoniae R6

87.946

99.115

0.872
  ciaR Streptococcus pneumoniae Rx1

87.946

99.115

0.872
  ciaR Streptococcus mutans UA159

88.235

97.788

0.863
  vicR Streptococcus mutans UA159

35.622

100

0.367
  covR Lactococcus lactis subsp. lactis strain DGCC12653

36.607

99.115

0.363

Multiple sequence alignment