Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACL43R_RS02230 Genome accession   NZ_CP180647
Coordinates   454317..455012 (+) Length   231 a.a.
NCBI ID   WP_017368870.1    Uniprot ID   A0A9Q8Y2F9
Organism   Lactococcus formosensis strain JAL11     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 449317..460012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACL43R_RS02205 (ACL43R_02205) - 449540..450241 (+) 702 WP_017368868.1 DeoR/GlpR family DNA-binding transcription regulator -
  ACL43R_RS02210 (ACL43R_02210) pfkB 450238..451155 (+) 918 WP_416037667.1 1-phosphofructokinase -
  ACL43R_RS02215 (ACL43R_02215) - 451189..453093 (+) 1905 WP_096368615.1 fructose-specific PTS transporter subunit EIIC -
  ACL43R_RS02220 (ACL43R_02220) - 453205..453447 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  ACL43R_RS02225 (ACL43R_02225) - 453665..454216 (+) 552 WP_416037668.1 YceD family protein -
  ACL43R_RS02230 (ACL43R_02230) covR 454317..455012 (+) 696 WP_017368870.1 response regulator transcription factor Regulator
  ACL43R_RS02235 (ACL43R_02235) covS 455100..456590 (+) 1491 WP_270740608.1 HAMP domain-containing histidine kinase Regulator
  ACL43R_RS02240 (ACL43R_02240) - 456986..458557 (+) 1572 WP_416037669.1 ABC transporter permease subunit -
  ACL43R_RS02245 (ACL43R_02245) - 458558..459295 (+) 738 WP_017368873.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 27023.75 Da        Isoelectric Point: 5.2713

>NTDB_id=1097147 ACL43R_RS02230 WP_017368870.1 454317..455012(+) (covR) [Lactococcus formosensis strain JAL11]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQDNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTVEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=1097147 ACL43R_RS02230 WP_017368870.1 454317..455012(+) (covR) [Lactococcus formosensis strain JAL11]
ATGAATTCATCTAAACGTATTTTAATTATCGAGGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGGTATCAAACTGCGGTTCAAGACAATGGTCGTAAAGGTCTTGAAGAAGCGATGTCAAAAGATTACGATTTGATTTTGC
TTGACTTAATGCTCCCAGAACTGGATGGCTTTGAAGTTGCACGACGCTTACGCCGTGAAAAAGATACACATATTATCATG
ATGACTGCACGTGATTCAACAATGGACCGTGTTGCTGGTCTTGATATTGGAGCGGATGATTATATTACAAAACCATTCGC
AATTGAAGAGTTGTTAGCACGTGTGCGTTCACTCTTCCGTCGTGAAGATCATATCCATACTGTTGAAAAGTCAGACAACA
CTTCATTCCGTGACTTGGTAATTGATAAAACAAACCGCACAGTACACCGTGGTAAAAAAGTCATTGACCTTACACGTCGT
GAGTACGACTTACTCTTGACTTTGATGCAAAATGTGGGGGATGTCGTAACACGCGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTTGACGTTTATATCCGTTACCTACGTAACAAGATTGATGTCGAAGGCCGTG
AAAGTTATATCCAAACTGTTCGTGGCATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-116)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

88.646

99.134

0.879
  covR Streptococcus salivarius strain HSISS4

66.81

100

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424

Multiple sequence alignment