Detailed information NTG1097148

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: ACL43R_RS02235
• Genome accession: NZ_CP180647
• Coordinates: 455100..456590 (+)
• Length: 496 a.a.
• NCBI ID: WP_270740608.1
• Uniprot ID: -
• Organism: Lactococcus formosensis strain JAL11
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 450100..461590

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACL43R_RS02210 (ACL43R_02210)	pfkB	450238..451155 (+)	918	WP_416037667.1	1-phosphofructokinase	-
ACL43R_RS02215 (ACL43R_02215)	-	451189..453093 (+)	1905	WP_096368615.1	fructose-specific PTS transporter subunit EIIC	-
ACL43R_RS02220 (ACL43R_02220)	-	453205..453447 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
ACL43R_RS02225 (ACL43R_02225)	-	453665..454216 (+)	552	WP_416037668.1	YceD family protein	-
ACL43R_RS02230 (ACL43R_02230)	covR	454317..455012 (+)	696	WP_017368870.1	response regulator transcription factor	Regulator
ACL43R_RS02235 (ACL43R_02235)	covS	455100..456590 (+)	1491	WP_270740608.1	HAMP domain-containing histidine kinase	Regulator
ACL43R_RS02240 (ACL43R_02240)	-	456986..458557 (+)	1572	WP_416037669.1	ABC transporter permease subunit	-
ACL43R_RS02245 (ACL43R_02245)	-	458558..459295 (+)	738	WP_017368873.1	amino acid ABC transporter ATP-binding protein	-
ACL43R_RS02250 (ACL43R_02250)	murD	459434..460795 (+)	1362	WP_279362653.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56900.91 Da
• Isoelectric Point: 5.0530

>NTDB_id=1097148 ACL43R_RS02235 WP_270740608.1 455100..456590(+) (covS) [Lactococcus formosensis strain JAL11]
MVKFFDSKKKKTETLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMRALNNVEQSLSQSVNKLS
EENLANYLAYAKGYTASSQGRENELETLGSMIGSRKSFYVFDVGENLIYSTNSYGFPLRKDVGDSSQAVRTFGEYSGYLV
ERPVHSKKTGELIGYVQAFYDMSYYYSVRTKLLVALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLESIDFQDEDLICDPTEVSNFLKKNFLLIHPDLKLTVENDLPSGRLAHIYPNHYEQGLKILIDNAI
KYSPEDRQEVKIHLEEDDEYIITTVEDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYEGDVSVTS
VVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=1097148 ACL43R_RS02235 WP_270740608.1 455100..456590(+) (covS) [Lactococcus formosensis strain JAL11]
ATGGTAAAATTTTTTGATTCTAAGAAGAAAAAAACAGAAACTCTTCCCGAGCGTAAGCGGAGCATCATGCTACGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACTTTCACTATTTTTACAGTATTGGTTTATCAACTAACGATAACTACTTTCA
TCAATTCTGAAAAAGAGGATATGATGAGGGCTTTAAATAATGTTGAACAAAGTCTGTCCCAATCGGTAAACAAACTGTCG
GAAGAAAATCTTGCGAATTATTTGGCTTATGCCAAAGGCTATACAGCCTCCAGTCAGGGAAGAGAAAATGAACTTGAAAC
ACTAGGAAGTATGATTGGTTCAAGAAAGTCCTTTTATGTCTTCGATGTAGGTGAGAACCTGATTTACTCGACCAATTCGT
ATGGTTTTCCTCTAAGGAAAGATGTGGGTGATTCATCGCAAGCTGTACGTACATTTGGCGAATATTCTGGTTATTTGGTT
GAGCGACCTGTGCATTCTAAAAAAACGGGTGAACTGATCGGCTATGTACAGGCTTTTTATGATATGAGCTATTATTATAG
TGTGCGTACAAAGCTACTTGTTGCCTTGATTATCTTAGAAATTATAGCTCTCTTTATAGCTCAGTTTGTTGGTTACTTTA
TGGCGAGTCGCTATATCAAGCCTTTGGAACGTTTGCACGATGCAATCACTACACGTGCCAATAATTTGAAAGCAGATTTC
AAACCTGTCGTTATTCAGACAGGGGATGAAATTGAGGAACTTGCAACAGTTTATAATGATATGATGATCAAGCTTAATGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCCGATGTCAGTCATGAGTTACGGACGCCACTTGCAGTTTTGGATGGGCATT
TGAATCTCTTGAATCGTTGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTTAGT
ACGATGAGAACGATGTTGGAAGAGATGCTCGCATTGGCGCGTCTTGAAAGCATTGATTTTCAAGATGAAGACCTAATCTG
TGATCCGACAGAAGTTTCGAATTTTCTTAAGAAAAATTTTCTACTCATCCATCCTGATTTAAAGTTAACTGTTGAAAATG
ACTTGCCATCAGGAAGATTAGCACATATATATCCCAACCATTATGAGCAAGGTTTGAAAATATTGATTGATAATGCGATA
AAATACTCGCCTGAAGATCGTCAAGAAGTCAAGATACATCTTGAAGAAGATGATGAATATATCATTACAACTGTGGAGGA
CCGTGGTTATGGTATTAGCCAAGAAGATTTAAAACATGTATTTGAACGTTTCTTCCGTGCGGATAAAGCACGAAATCGAG
ATATAGGAGGAACTGGGCTTGGGCTATCTATTATTCAACGTATAGTGGAGAACTATGAGGGAGATGTTAGCGTGACTTCC
GTTGTAGGAGAGGGTTCAAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• HAMP domain (HAMP) (214-266)

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• ArlS sensor domain (ArlS_N) (52-190)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.823	100	0.56