Detailed information NTG1094901

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: ACMATP_RS01740
• Genome accession: NZ_CP180259
• Coordinates: 378057..380207 (+)
• Length: 716 a.a.
• NCBI ID: WP_027821502.1
• Uniprot ID: L7ZAH2
• Organism: Lactiplantibacillus plantarum strain V2
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 373057..385207

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACMATP_RS01710 (ACMATP_01710)	-	374003..374170 (+)	168	WP_153302738.1	hypothetical protein	-
ACMATP_RS01715 (ACMATP_01715)	-	374188..375528 (+)	1341	WP_027821504.1	GHKL domain-containing protein	-
ACMATP_RS01720 (ACMATP_01720)	-	375529..376272 (+)	744	WP_015825122.1	response regulator transcription factor	-
ACMATP_RS01725 (ACMATP_01725)	-	376566..377339 (-)	774	WP_027821503.1	CPBP family intramembrane glutamic endopeptidase	-
ACMATP_RS01730 (ACMATP_01730)	plnF	377438..377596 (-)	159	WP_003643811.1	two-peptide bacteriocin plantaricin EF subunit PlnF	-
ACMATP_RS01735 (ACMATP_01735)	plnE	377621..377791 (-)	171	WP_003641985.1	two-peptide bacteriocin plantaricin EF subunit PlnE	-
ACMATP_RS01740 (ACMATP_01740)	comA	378057..380207 (+)	2151	WP_027821502.1	peptide cleavage/export ABC transporter	Regulator
ACMATP_RS01745 (ACMATP_01745)	-	380224..381600 (+)	1377	WP_027821501.1	HlyD family secretion protein	-
ACMATP_RS01750 (ACMATP_01750)	-	381690..382379 (+)	690	WP_027821500.1	CPBP family intramembrane glutamic endopeptidase	-
ACMATP_RS01755 (ACMATP_01755)	-	382447..383115 (+)	669	WP_027821499.1	CPBP family intramembrane glutamic endopeptidase	-
ACMATP_RS01760 (ACMATP_01760)	-	383202..383882 (+)	681	WP_027821498.1	CPBP family intramembrane glutamic endopeptidase	-
ACMATP_RS01765 (ACMATP_01765)	-	383976..384662 (+)	687	WP_027821497.1	CPBP family intramembrane glutamic endopeptidase	-
ACMATP_RS01770 (ACMATP_01770)	-	384800..385003 (+)	204	WP_027821496.1	hypothetical protein	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 79956.67 Da
• Isoelectric Point: 6.6530

>NTDB_id=1094901 ACMATP_RS01740 WP_027821502.1 378057..380207(+) (comA) [Lactiplantibacillus plantarum strain V2]
MHWRNYVAQVDEMDCGVAALAMILKNYGSTTSLAYLRNIAKTSLEGTTALGLVKTAEKLGFETKAIQADMSLFDVQDLPL
PFIVHVTKNGDLQHFYVVVKTSKTHVVIADPDPTVAVISMSKERFESEWSGVALFFAPKSEYKPVKQDKGSLWGFIPSLL
KQRRLVINIVLAAVLITIISICGSYFLQAVIDTYIPNNMHSTLAVVAIGLIVFYTFQAIFTYAQNFLLAVLGQRLSIEII
LGYIRHVFELPMSFFATRRTGEIVSRFTDASKIIDALASTIVSLFLDVSIVIIMGAILVIQNMTLFWITLLSLPIYAVVI
LAFNKSFERLNQKEMESNAILSSAIIEDLHGIETVKALNGETERYQKIDSEFVDYLRKSLAYLKADTLQQALKLFIQLVL
EVVVLWVGANLVIHNQLSVGELMTYNALLAYFVNPLQNIINLQTKLQSAKVANNRLNEVYLVASEFEASRPIHNESQLNG
DIKLQGVSYRYGYGENVLDDVNLTIRQHDKVAIVGMSGSGKSTLVKLLIDFYQPNSGDVMLNGFNVKNIDKHTLRTHINY
IPQEPYIFSATIEENLRLGNRSGITEKDIAKACQLALIDTDINKMAMQYQTKLDENGNTLSGGQRQRLTIARALLSPAQV
LIFDESTSGLDAITEKQLIDNLVAMTDKTIIFIAHRLSIAKRTNHIIVLHDGRVAEEGTHAALLNEHGYYYDLINS

Nucleotide

• Length: 2151 bp

>NTDB_id=1094901 ACMATP_RS01740 WP_027821502.1 378057..380207(+) (comA) [Lactiplantibacillus plantarum strain V2]
ATGCATTGGAGAAACTATGTTGCGCAAGTTGACGAGATGGACTGTGGGGTCGCAGCTTTAGCAATGATTTTGAAAAATTA
TGGTTCGACAACATCATTGGCCTATCTAAGAAATATTGCTAAAACGAGTTTAGAAGGGACTACGGCATTAGGATTAGTAA
AAACGGCCGAAAAGTTAGGTTTTGAAACCAAAGCAATTCAAGCAGATATGAGTCTTTTCGATGTCCAAGATTTACCATTG
CCATTCATTGTGCATGTTACCAAAAATGGGGATCTACAGCATTTTTATGTTGTTGTAAAAACCTCGAAAACGCATGTCGT
GATTGCTGATCCGGACCCAACAGTTGCGGTTATCAGTATGTCAAAGGAACGGTTTGAAAGCGAATGGTCCGGAGTTGCCC
TTTTCTTTGCACCGAAGTCGGAATATAAGCCAGTTAAGCAAGATAAGGGCTCACTATGGGGATTTATTCCAAGCTTATTA
AAGCAGCGCCGACTGGTTATTAATATTGTGCTTGCTGCAGTTTTAATCACGATTATTAGTATCTGTGGGTCTTATTTCTT
ACAAGCGGTGATTGATACTTATATTCCTAATAATATGCACAGTACATTGGCAGTGGTGGCAATTGGTCTAATCGTTTTTT
ATACCTTTCAGGCTATCTTTACTTATGCCCAGAATTTTTTATTGGCGGTTTTAGGTCAACGACTTTCGATTGAAATTATT
TTAGGCTATATTCGGCACGTCTTTGAATTGCCAATGAGTTTTTTTGCCACTCGGCGGACGGGGGAAATTGTTTCAAGGTT
TACGGATGCCAGTAAGATTATTGATGCGTTAGCTAGCACAATTGTTTCGCTGTTTTTAGATGTCAGCATCGTTATTATTA
TGGGGGCAATCTTGGTAATCCAGAATATGACACTTTTTTGGATTACGTTACTCTCGTTGCCAATCTACGCGGTTGTCATC
TTAGCCTTTAATAAATCCTTTGAACGATTGAATCAAAAGGAAATGGAAAGCAATGCTATTTTGAGTTCAGCCATTATTGA
GGATCTTCATGGGATTGAAACTGTTAAGGCGCTGAATGGTGAGACGGAACGTTATCAGAAAATTGATTCAGAATTTGTTG
ATTATCTACGTAAGAGTTTAGCCTATCTTAAAGCGGATACTTTGCAACAGGCATTAAAACTGTTTATACAGTTAGTCTTA
GAAGTTGTTGTTCTATGGGTGGGCGCCAATCTCGTCATTCATAATCAGTTATCAGTTGGGGAGCTCATGACATATAATGC
TTTATTAGCCTATTTTGTTAATCCACTACAGAATATTATTAATTTGCAGACTAAGCTTCAAAGCGCTAAGGTCGCTAACA
ACCGGTTAAATGAAGTGTATTTGGTCGCTAGTGAATTTGAGGCGTCACGGCCAATTCATAATGAAAGTCAATTAAATGGT
GATATTAAGTTACAAGGGGTCAGCTATCGTTATGGTTACGGTGAAAATGTCTTAGATGATGTTAATTTGACGATTCGACA
ACATGATAAGGTTGCAATTGTGGGGATGAGTGGCTCTGGCAAGTCCACGTTAGTTAAATTGCTTATTGATTTTTATCAGC
CGAATAGTGGTGATGTCATGCTGAACGGCTTCAACGTTAAGAACATCGATAAGCATACATTGCGGACCCATATTAACTAC
ATCCCGCAGGAACCATACATCTTTTCAGCGACCATTGAAGAAAATTTAAGATTAGGTAATCGCAGCGGTATTACTGAGAA
AGATATTGCGAAGGCTTGCCAATTGGCGTTAATTGATACAGATATTAATAAAATGGCCATGCAATACCAAACTAAGCTAG
ATGAGAATGGTAATACACTATCAGGTGGTCAGCGACAACGATTAACGATTGCGAGAGCGTTATTATCTCCCGCTCAAGTC
TTGATATTTGATGAGTCGACGAGTGGACTGGATGCAATTACTGAGAAACAATTAATCGATAATTTAGTGGCAATGACTGA
CAAGACGATTATTTTTATTGCCCACCGGCTGTCGATTGCAAAGCGGACGAATCATATCATCGTTCTGCATGATGGTCGGG
TCGCTGAAGAGGGGACCCATGCGGCATTGTTGAATGAACATGGTTACTATTACGACTTGATCAATAGCTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (5-140)

• ABC transporter transmembrane region (ABC_membrane) (166-436)

• ABC transporter (ABC_tran) (498-648)

3D structure

• AlphaFold DB: L7ZAH2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	59.046	99.581	0.588
comA	Streptococcus pneumoniae Rx1	58.766	99.581	0.585
comA	Streptococcus pneumoniae D39	58.766	99.581	0.585
comA	Streptococcus pneumoniae R6	58.766	99.581	0.585
comA	Streptococcus pneumoniae TIGR4	58.626	99.581	0.584
comA	Streptococcus mitis SK321	58.485	99.581	0.582
comA	Streptococcus gordonii str. Challis substr. CH1	57.242	100	0.574
comA/nlmT	Streptococcus mutans UA159	54.735	100	0.549