Detailed information NTG0109078

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: ACAM21_RS10055
• Genome accession: NZ_AP031395
• Coordinates: 1917129..1917590 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250548.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16P29
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1912129..1922590

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM21_RS10020 (SPNE16P29_19480)	-	1912440..1913264 (-)	825	WP_369608070.1	membrane protein insertase YidC	-
ACAM21_RS10025 (SPNE16P29_19490)	rnpA	1913239..1913610 (-)	372	WP_000739246.1	ribonuclease P protein component	-
ACAM21_RS10030	-	1913627..1913758 (-)	132	WP_000768903.1	hypothetical protein	-
ACAM21_RS10035 (SPNE16P29_19500)	-	1913759..1914949 (-)	1191	WP_000167759.1	acetate kinase	-
ACAM21_RS10040 (SPNE16P29_19510)	comYH	1915000..1915953 (-)	954	WP_000345123.1	class I SAM-dependent methyltransferase	Machinery gene
ACAM21_RS10045 (SPNE16P29_19520)	-	1916014..1916601 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
ACAM21_RS10050 (SPNE16P29_19530)	comGG/cglG	1916738..1917151 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
ACAM21_RS10055 (SPNE16P29_19540)	comGF/cglF	1917129..1917590 (-)	462	WP_000250548.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACAM21_RS10060 (SPNE16P29_19550)	comGE/cglE	1917553..1917855 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
ACAM21_RS10065 (SPNE16P29_19560)	comGD/cglD	1917818..1918222 (-)	405	WP_000588007.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACAM21_RS10070 (SPNE16P29_19570)	comGC/cglC	1918215..1918541 (-)	327	WP_000738624.1	competence type IV pilus major pilin ComGC	Machinery gene
ACAM21_RS10075 (SPNE16P29_19580)	comGB/cglB	1918543..1919559 (-)	1017	WP_073177425.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACAM21_RS10080 (SPNE16P29_19590)	comGA/cglA/cilD	1919507..1920448 (-)	942	WP_000249559.1	competence type IV pilus ATPase ComGA	Machinery gene
ACAM21_RS10085 (SPNE16P29_19600)	-	1920524..1920889 (-)	366	WP_000286415.1	DUF1033 family protein	-
ACAM21_RS10090 (SPNE16P29_19610)	-	1921156..1922411 (+)	1256	WP_088804233.1	ISL3 family transposase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17851.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=109078 ACAM21_RS10055 WP_000250548.1 1917129..1917590(-) (comGF/cglF) [Streptococcus pneumoniae strain 16P29]
MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVESN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=109078 ACAM21_RS10055 WP_000250548.1 1917129..1917590(-) (comGF/cglF) [Streptococcus pneumoniae strain 16P29]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTGCT
CGTCATCAGTGGAGGCTTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAAGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae D39	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae R6	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae TIGR4	93.464	100	0.935
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909
comYF	Streptococcus mutans UA159	41.791	87.582	0.366
comYF	Streptococcus mutans UA140	41.791	87.582	0.366