Detailed information NTG0109079

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: ACAM21_RS10060
• Genome accession: NZ_AP031395
• Coordinates: 1917553..1917855 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413380.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16P29
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1912553..1922855

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM21_RS10025 (SPNE16P29_19490)	rnpA	1913239..1913610 (-)	372	WP_000739246.1	ribonuclease P protein component	-
ACAM21_RS10030	-	1913627..1913758 (-)	132	WP_000768903.1	hypothetical protein	-
ACAM21_RS10035 (SPNE16P29_19500)	-	1913759..1914949 (-)	1191	WP_000167759.1	acetate kinase	-
ACAM21_RS10040 (SPNE16P29_19510)	comYH	1915000..1915953 (-)	954	WP_000345123.1	class I SAM-dependent methyltransferase	Machinery gene
ACAM21_RS10045 (SPNE16P29_19520)	-	1916014..1916601 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
ACAM21_RS10050 (SPNE16P29_19530)	comGG/cglG	1916738..1917151 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
ACAM21_RS10055 (SPNE16P29_19540)	comGF/cglF	1917129..1917590 (-)	462	WP_000250548.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACAM21_RS10060 (SPNE16P29_19550)	comGE/cglE	1917553..1917855 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
ACAM21_RS10065 (SPNE16P29_19560)	comGD/cglD	1917818..1918222 (-)	405	WP_000588007.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACAM21_RS10070 (SPNE16P29_19570)	comGC/cglC	1918215..1918541 (-)	327	WP_000738624.1	competence type IV pilus major pilin ComGC	Machinery gene
ACAM21_RS10075 (SPNE16P29_19580)	comGB/cglB	1918543..1919559 (-)	1017	WP_073177425.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACAM21_RS10080 (SPNE16P29_19590)	comGA/cglA/cilD	1919507..1920448 (-)	942	WP_000249559.1	competence type IV pilus ATPase ComGA	Machinery gene
ACAM21_RS10085 (SPNE16P29_19600)	-	1920524..1920889 (-)	366	WP_000286415.1	DUF1033 family protein	-
ACAM21_RS10090 (SPNE16P29_19610)	-	1921156..1922411 (+)	1256	WP_088804233.1	ISL3 family transposase	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11135.11 Da
• Isoelectric Point: 9.7273

>NTDB_id=109079 ACAM21_RS10060 WP_000413380.1 1917553..1917855(-) (comGE/cglE) [Streptococcus pneumoniae strain 16P29]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=109079 ACAM21_RS10060 WP_000413380.1 1917553..1917855(-) (comGE/cglE) [Streptococcus pneumoniae strain 16P29]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus mitis NCTC 12261	99	100	0.99
comGE/cglE	Streptococcus pneumoniae Rx1	99	100	0.99
comGE/cglE	Streptococcus pneumoniae D39	99	100	0.99
comGE/cglE	Streptococcus pneumoniae R6	99	100	0.99
comGE/cglE	Streptococcus pneumoniae TIGR4	99	100	0.99
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	43.333	90	0.39
comYE	Streptococcus mutans UA159	43.333	90	0.39