Detailed information NTG0109030

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ACAM21_RS02845
• Genome accession: NZ_AP031395
• Coordinates: 535535..537211 (-)
• Length: 558 a.a.
• NCBI ID: WP_196299874.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16P29
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 530535..542211

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM21_RS02815 (SPNE16P29_05500)	-	530867..531196 (-)	330	WP_000132583.1	hypothetical protein	-
ACAM21_RS02820 (SPNE16P29_05510)	-	531473..531811 (+)	339	WP_000682136.1	LytTR family DNA-binding domain-containing protein	-
ACAM21_RS02825 (SPNE16P29_05520)	comE/blpR	531816..532553 (+)	738	WP_001219136.1	LytTR family DNA-binding domain-containing protein	Regulator
ACAM21_RS02830 (SPNE16P29_05530)	-	532567..533907 (+)	1341	WP_001017643.1	sensor histidine kinase	-
ACAM21_RS02835 (SPNE16P29_05540)	blpC	533978..534106 (-)	129	WP_000358815.1	quorum-sensing system pheromone BlpC	-
ACAM21_RS02840 (SPNE16P29_05550)	-	534163..535524 (-)	1362	Protein_559	bacteriocin secretion accessory protein	-
ACAM21_RS02845 (SPNE16P29_05570)	comA/nlmT	535535..537211 (-)	1677	WP_196299874.1	peptide cleavage/export ABC transporter	Regulator
ACAM21_RS02850 (SPNE16P29_05580)	comA/nlmT	537105..537692 (-)	588	WP_000205166.1	cysteine peptidase family C39 domain-containing protein	Regulator
ACAM21_RS02855 (SPNE16P29_05590)	blpI	537974..538171 (+)	198	WP_001093261.1	bacteriocin-like peptide BlpI	-
ACAM21_RS02860 (SPNE16P29_05610)	blpJ	538638..538907 (+)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
ACAM21_RS02865 (SPNE16P29_05620)	blpU	538976..539206 (+)	231	WP_000379967.1	bacteriocin-like peptide BlpU	-
ACAM21_RS02870	-	539209..539328 (+)	120	WP_000346298.1	PncF family bacteriocin immunity protein	-
ACAM21_RS02875 (SPNE16P29_05630)	-	539625..539789 (+)	165	WP_000727118.1	hypothetical protein	-
ACAM21_RS02880 (SPNE16P29_05640)	-	539786..540190 (+)	405	WP_000846944.1	hypothetical protein	-
ACAM21_RS02885	-	540393..541198 (+)	806	Protein_568	IS5 family transposase	-
ACAM21_RS02890 (SPNE16P29_05670)	blpM	541348..541602 (+)	255	WP_000379877.1	two-peptide bacteriocin subunit BlpM	-
ACAM21_RS02895 (SPNE16P29_05680)	blpN	541618..541821 (+)	204	WP_001099492.1	two-peptide bacteriocin subunit BlpN	-

Sequence

Protein

• Length: 558 a.a.
• Molecular weight: 62923.20 Da
• Isoelectric Point: 6.7844

>NTDB_id=109030 ACAM21_RS02845 WP_196299874.1 535535..537211(-) (comA/nlmT) [Streptococcus pneumoniae strain 16P29]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 1677 bp

>NTDB_id=109030 ACAM21_RS02845 WP_196299874.1 535535..537211(-) (comA/nlmT) [Streptococcus pneumoniae strain 16P29]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGATCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGCCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (341-490)

• ABC transporter transmembrane region (ABC_membrane) (10-279)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.89	99.821	0.728
comA	Streptococcus mitis NCTC 12261	67.204	100	0.672
comA	Streptococcus pneumoniae D39	66.846	100	0.668
comA	Streptococcus pneumoniae R6	66.846	100	0.668
comA	Streptococcus pneumoniae Rx1	66.846	100	0.668
comA	Streptococcus mitis SK321	66.667	100	0.667
comA	Streptococcus gordonii str. Challis substr. CH1	66.547	100	0.667
comA	Streptococcus pneumoniae TIGR4	66.487	100	0.665