Detailed information NTG0108999

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: ACAM23_RS10050
• Genome accession: NZ_AP031394
• Coordinates: 1916575..1916877 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413380.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16P28
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1911575..1921877

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM23_RS10015 (SPNE16P28_19430)	rnpA	1912261..1912632 (-)	372	WP_000739246.1	ribonuclease P protein component	-
ACAM23_RS10020	-	1912649..1912780 (-)	132	WP_000768903.1	hypothetical protein	-
ACAM23_RS10025 (SPNE16P28_19440)	-	1912781..1913971 (-)	1191	WP_000167759.1	acetate kinase	-
ACAM23_RS10030 (SPNE16P28_19450)	comYH	1914022..1914975 (-)	954	WP_000345123.1	class I SAM-dependent methyltransferase	Machinery gene
ACAM23_RS10035 (SPNE16P28_19460)	-	1915036..1915623 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
ACAM23_RS10040 (SPNE16P28_19470)	comGG/cglG	1915760..1916173 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
ACAM23_RS10045 (SPNE16P28_19480)	comGF/cglF	1916151..1916612 (-)	462	WP_000250548.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACAM23_RS10050 (SPNE16P28_19490)	comGE/cglE	1916575..1916877 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
ACAM23_RS10055 (SPNE16P28_19500)	comGD/cglD	1916840..1917244 (-)	405	WP_000588007.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACAM23_RS10060 (SPNE16P28_19510)	comGC/cglC	1917237..1917563 (-)	327	WP_000738624.1	competence type IV pilus major pilin ComGC	Machinery gene
ACAM23_RS10065 (SPNE16P28_19520)	comGB/cglB	1917565..1918581 (-)	1017	WP_073177425.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACAM23_RS10070 (SPNE16P28_19530)	comGA/cglA/cilD	1918529..1919470 (-)	942	WP_000249559.1	competence type IV pilus ATPase ComGA	Machinery gene
ACAM23_RS10075 (SPNE16P28_19540)	-	1919546..1919911 (-)	366	WP_000286415.1	DUF1033 family protein	-
ACAM23_RS10080 (SPNE16P28_19550)	-	1920178..1921433 (+)	1256	WP_088804233.1	ISL3 family transposase	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11135.11 Da
• Isoelectric Point: 9.7273

>NTDB_id=108999 ACAM23_RS10050 WP_000413380.1 1916575..1916877(-) (comGE/cglE) [Streptococcus pneumoniae strain 16P28]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=108999 ACAM23_RS10050 WP_000413380.1 1916575..1916877(-) (comGE/cglE) [Streptococcus pneumoniae strain 16P28]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus mitis NCTC 12261	99	100	0.99
comGE/cglE	Streptococcus pneumoniae Rx1	99	100	0.99
comGE/cglE	Streptococcus pneumoniae D39	99	100	0.99
comGE/cglE	Streptococcus pneumoniae R6	99	100	0.99
comGE/cglE	Streptococcus pneumoniae TIGR4	99	100	0.99
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	43.333	90	0.39
comYE	Streptococcus mutans UA159	43.333	90	0.39