Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ACLSIV_RS01080 Genome accession   NZ_CP178385
Coordinates   198480..199727 (-) Length   415 a.a.
NCBI ID   WP_412921736.1    Uniprot ID   -
Organism   Lactococcus raffinolactis strain GCULR     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 193480..204727
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLSIV_RS01045 (ACLSIV_01045) - 193975..194721 (+) 747 WP_096039852.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ACLSIV_RS01050 (ACLSIV_01050) - 194714..195004 (+) 291 WP_096039853.1 GIY-YIG nuclease family protein -
  ACLSIV_RS01055 (ACLSIV_01055) - 195065..195289 (-) 225 WP_061775128.1 DUF1797 family protein -
  ACLSIV_RS01060 (ACLSIV_01060) - 195350..196681 (-) 1332 WP_096039854.1 glycosyltransferase family 4 protein -
  ACLSIV_RS01065 (ACLSIV_01065) - 196781..197779 (-) 999 WP_061775126.1 glycosyltransferase -
  ACLSIV_RS01075 (ACLSIV_01075) - 198245..198439 (+) 195 WP_412921734.1 hypothetical protein -
  ACLSIV_RS01080 (ACLSIV_01080) htrA 198480..199727 (-) 1248 WP_412921736.1 S1C family serine protease Regulator
  ACLSIV_RS01085 (ACLSIV_01085) rlmH 200024..200500 (+) 477 WP_096039856.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACLSIV_RS01090 (ACLSIV_01090) - 200497..201159 (+) 663 WP_061775122.1 DNA alkylation repair protein -
  ACLSIV_RS01095 (ACLSIV_01095) - 201224..201901 (+) 678 WP_167839619.1 YoaK family protein -
  ACLSIV_RS01100 (ACLSIV_01100) guaB 202121..203602 (+) 1482 WP_061775120.1 IMP dehydrogenase -
  ACLSIV_RS01105 (ACLSIV_01105) - 203877..204722 (+) 846 WP_167839620.1 PRD domain-containing protein -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 43465.78 Da        Isoelectric Point: 5.3584

>NTDB_id=1089275 ACLSIV_RS01080 WP_412921736.1 198480..199727(-) (htrA) [Lactococcus raffinolactis strain GCULR]
MKNSKKTTVKLIAAGIIGGAVSLGGNIAYDHFTGDTPIKTNQTSTTKVSDVSYKVSSSTTKAIAKVSDAVVSVINYQKAS
SSNSLDDLFGDSSSTNKDNAKEQPAGEGSGVIYKKDGDYAYIVTNNHVVDGASSLEIMLSNGNKVKGTLVGKDAYSDLAV
IKIPSKEVTKVAEFGDSSKLTVGEPAIAIGSPLGSEYANSATEGIISSLSRKVIMQNESNETVNVNAIQTDAAINPGNSG
GALINVEGQVIGINSSKISATGSSSRDVSVEGMGFAIPSNDVVEIISKLEKDGEIKRPALGVQMVDLTGINSRYIDELKL
PDSVTAGVVVAKVQKGLPADTAGLKKYDVITKIGDTKVTTSTELQSALYKYNVGDEMKVTYYREGKEKTATVKLATSSDK
LDFKDAESAKAEQDK

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=1089275 ACLSIV_RS01080 WP_412921736.1 198480..199727(-) (htrA) [Lactococcus raffinolactis strain GCULR]
ATGAAAAATAGTAAAAAAACTACTGTAAAATTAATCGCTGCTGGGATTATCGGTGGTGCTGTTTCATTAGGTGGTAATAT
CGCCTACGACCATTTTACGGGTGATACGCCTATCAAGACGAATCAAACCAGCACGACCAAAGTGTCTGATGTTTCTTATA
AAGTATCAAGTAGTACGACTAAAGCGATTGCCAAAGTATCTGATGCCGTTGTCTCTGTCATTAATTATCAAAAAGCGTCG
TCAAGCAACTCATTAGATGATCTTTTTGGTGATAGCTCATCTACTAATAAGGATAATGCTAAAGAACAACCCGCAGGTGA
AGGCTCTGGTGTCATCTATAAAAAAGACGGTGATTACGCTTATATCGTTACCAACAACCACGTCGTTGATGGTGCAAGCT
CACTAGAAATCATGCTATCAAATGGTAATAAGGTCAAAGGTACTTTAGTCGGGAAAGATGCTTATAGCGATTTAGCGGTC
ATTAAAATTCCATCTAAAGAAGTCACAAAAGTTGCTGAATTCGGCGATTCTTCCAAGCTTACTGTTGGAGAGCCCGCCAT
TGCTATCGGCTCTCCTCTAGGAAGTGAATATGCTAACTCAGCCACTGAAGGGATTATCTCTAGTCTATCACGCAAGGTTA
TCATGCAAAATGAAAGCAATGAAACCGTCAATGTTAATGCCATTCAAACCGATGCCGCGATTAATCCCGGCAACTCTGGT
GGTGCTTTGATCAACGTCGAAGGTCAAGTCATCGGCATCAACTCAAGCAAGATCTCTGCAACAGGTTCATCTTCAAGAGA
TGTTTCTGTTGAAGGGATGGGCTTCGCCATTCCATCCAATGATGTCGTTGAAATTATCAGTAAACTCGAAAAAGACGGTG
AAATCAAGCGCCCAGCACTCGGCGTGCAAATGGTTGATCTCACTGGCATTAACTCGCGCTATATCGACGAGCTCAAACTT
CCTGACTCTGTCACAGCAGGTGTCGTGGTCGCCAAAGTTCAAAAAGGTCTACCAGCCGACACTGCGGGACTTAAAAAATA
TGATGTGATCACGAAAATTGGTGATACTAAAGTGACAACTAGTACTGAACTTCAAAGCGCGCTTTACAAATACAATGTCG
GAGACGAGATGAAAGTCACTTACTACCGTGAGGGTAAAGAAAAAACAGCAACTGTTAAACTTGCTACATCCTCTGATAAG
TTAGACTTTAAAGATGCTGAGTCTGCCAAGGCTGAACAAGATAAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(108-253)

PDZ domain (PDZ_2)

(298-394)

Peptidase family M50 (Peptidase_M50)

(263-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

56.127

98.313

0.552
  htrA Streptococcus mutans UA159

57.979

90.602

0.525
  htrA Streptococcus mitis NCTC 12261

53.061

94.458

0.501
  htrA Streptococcus pneumoniae Rx1

55.493

85.542

0.475
  htrA Streptococcus pneumoniae D39

55.493

85.542

0.475
  htrA Streptococcus pneumoniae R6

55.493

85.542

0.475
  htrA Streptococcus pneumoniae TIGR4

55.493

85.542

0.475

Multiple sequence alignment