Detailed information
Bioinformatically predicted
Overview
| Name | comA | Type | Regulator |
| Locus tag | KCX75_RS01980 | Genome accession | NZ_CP177271 |
| Coordinates | 376010..378169 (-) | Length | 719 a.a. |
| NCBI ID | WP_003649216.1 | Uniprot ID | A0AB33C8C0 |
| Organism | Lactobacillus gasseri strain LG-145 | ||
| Function | processing and transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| IS/Tn | 374005..375054 | 376010..378169 | flank | 956 |
Gene organization within MGE regions
Location: 374005..378169
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KCX75_RS01970 (KCX75_01970) | - | 374005..375054 (-) | 1050 | WP_024273054.1 | IS30-like element ISLga1 family transposase | - |
| KCX75_RS01975 (KCX75_01975) | - | 375406..375999 (-) | 594 | WP_003649215.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| KCX75_RS01980 (KCX75_01980) | comA | 376010..378169 (-) | 2160 | WP_003649216.1 | peptide cleavage/export ABC transporter | Regulator |
Sequence
Protein
Download Length: 719 a.a. Molecular weight: 81069.37 Da Isoelectric Point: 7.7712
>NTDB_id=1086490 KCX75_RS01980 WP_003649216.1 376010..378169(-) (comA) [Lactobacillus gasseri strain LG-145]
MLFKYKSVYVPQVDEMDCGVACLAMILKQYHSRVSLAHLRHEARTNLEGTTALGLVKTAQKFNFKTEAVKADMSLFDENS
IQYPFIAHVLKQGELLHYYVVLKNAKNYLVIADPDPSVGVVKMPKDKFAQEWTGVALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYVFNSIFSYGQNFLLNILGQRLSI
DLNLRYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLSIVIVMGLVLAAQNMTLFGITLLALPIYA
VVILGFTKKFEKLNNEQMESNAVLSSSVIEDIQGIETIKALNSENTRYRRIDSQFVDYLKKSFKYSKTESLQTALKTFIQ
LSLNVIVLWVGAKIVMQGQLSIGQLMTFNALLAYFIDPLQSIINLQPRLQSASVAQNRLNEVYQVKSEFNQKATIEDRKL
LEGNIEYKNVDYSYGYGTDVLKDINLKISQGEKLTIVGMSGSGKSTMVKLLVDFFSPSKGQVTLNGHATSEIDKHTLRSY
VNYVPQTPYIFSGTVKENLLLGCRPDITEEDVIKACQIAEIDQEIANLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKKVIDNLMKLKDKTIIFIAHRLAIAERADKVVVIDHGQIVEEGSHSELMSKHGFYYDLVKG
MLFKYKSVYVPQVDEMDCGVACLAMILKQYHSRVSLAHLRHEARTNLEGTTALGLVKTAQKFNFKTEAVKADMSLFDENS
IQYPFIAHVLKQGELLHYYVVLKNAKNYLVIADPDPSVGVVKMPKDKFAQEWTGVALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYVFNSIFSYGQNFLLNILGQRLSI
DLNLRYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLSIVIVMGLVLAAQNMTLFGITLLALPIYA
VVILGFTKKFEKLNNEQMESNAVLSSSVIEDIQGIETIKALNSENTRYRRIDSQFVDYLKKSFKYSKTESLQTALKTFIQ
LSLNVIVLWVGAKIVMQGQLSIGQLMTFNALLAYFIDPLQSIINLQPRLQSASVAQNRLNEVYQVKSEFNQKATIEDRKL
LEGNIEYKNVDYSYGYGTDVLKDINLKISQGEKLTIVGMSGSGKSTMVKLLVDFFSPSKGQVTLNGHATSEIDKHTLRSY
VNYVPQTPYIFSGTVKENLLLGCRPDITEEDVIKACQIAEIDQEIANLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKKVIDNLMKLKDKTIIFIAHRLAIAERADKVVVIDHGQIVEEGSHSELMSKHGFYYDLVKG
Nucleotide
Download Length: 2160 bp
>NTDB_id=1086490 KCX75_RS01980 WP_003649216.1 376010..378169(-) (comA) [Lactobacillus gasseri strain LG-145]
ATGTTATTCAAATATAAATCCGTATACGTGCCACAAGTGGATGAGATGGATTGCGGCGTTGCTTGTCTAGCAATGATCTT
AAAGCAATATCATTCTCGCGTATCTTTAGCACATTTACGTCATGAAGCTCGTACTAATCTTGAAGGCACAACTGCTTTAG
GACTAGTGAAGACAGCACAAAAATTTAATTTCAAAACAGAAGCCGTAAAAGCAGATATGTCTTTATTTGATGAGAATAGT
ATTCAATATCCTTTTATTGCCCACGTCCTAAAACAAGGAGAACTACTTCATTATTACGTAGTTCTTAAAAATGCTAAGAA
TTATTTAGTAATTGCAGATCCTGATCCATCAGTTGGTGTAGTAAAGATGCCAAAAGACAAATTTGCTCAAGAATGGACTG
GTGTTGCACTCTTTATGGTTCCTAACGAAGACTTTGAACCAATCAAAGAAAAGAAGAATAATTTATGGTCTCTCTTTCCA
TATATGTTTAAACAAAAGCGGCTGATGATTAACATCATTTTAGCCGCTTTATTAATGACCATAATTAGTATCTGTAGTTC
ATATTTTGTTCAAGGAATAATTGATACTTACATTCCAGATGGAACCTATCAGACTCTTTCGATCTTAGCTGTTGGACTAT
TAATTGCTTATGTCTTTAATTCAATTTTTTCTTATGGACAGAATTTTTTATTAAATATTTTAGGTCAAAGATTAAGTATT
GATCTAAATCTGCGATACATCAGGCATATTTTTGAATTACCAATGGAATTCTTTGTAACAAGAAGAACGGGTGAAATTAC
TTCGCGTTTTTCTGATGCAAGTAGAATTATTGACGCTTTGGCAAGTACAGTTATTTCGCTCTTCTTAGACCTCTCAATTG
TGATTGTGATGGGATTAGTCTTAGCAGCACAAAATATGACATTATTTGGGATTACACTGTTAGCTTTGCCTATTTATGCA
GTTGTAATTCTAGGTTTTACTAAAAAGTTTGAAAAACTAAATAACGAACAAATGGAAAGTAATGCTGTTTTGAGTTCTTC
AGTTATTGAAGATATTCAAGGAATTGAAACTATTAAAGCTTTAAATAGTGAGAATACAAGATATAGAAGAATCGACAGTC
AGTTTGTAGATTACTTAAAGAAGTCATTTAAATATAGTAAGACTGAGAGTTTACAGACAGCACTCAAGACATTTATTCAA
TTATCTCTTAATGTAATTGTTCTTTGGGTTGGTGCAAAGATTGTAATGCAAGGACAATTGAGCATTGGTCAGTTAATGAC
GTTCAATGCATTGCTGGCATATTTCATTGATCCCTTGCAAAGTATTATTAATTTACAACCGCGACTTCAATCAGCTAGTG
TTGCTCAAAATCGATTAAATGAGGTCTATCAAGTAAAAAGTGAATTCAATCAGAAGGCTACTATTGAAGATCGTAAGCTC
CTAGAAGGAAATATTGAATATAAGAATGTGGATTATAGCTATGGTTATGGCACAGATGTCTTAAAAGATATTAATCTCAA
AATTAGCCAGGGCGAAAAATTAACGATTGTTGGAATGAGTGGTTCTGGAAAATCTACGATGGTTAAGTTGTTAGTAGATT
TCTTTTCGCCAAGTAAAGGTCAGGTTACATTAAATGGACATGCAACAAGTGAGATTGATAAGCATACGTTGCGGTCATAT
GTAAATTATGTACCTCAAACTCCATATATCTTTTCTGGAACAGTTAAAGAGAATTTGTTGTTAGGTTGTAGGCCAGATAT
CACTGAAGAAGATGTAATAAAGGCTTGTCAAATTGCTGAGATTGACCAAGAAATAGCTAATCTACCTTTGCAATTTGAAA
CAAAATTAGATGAAAATGCCAAAATTTTATCTGGTGGACAAAAACAAAGGTTAACTATTGCCCGGGCATTACTATCTCCT
GCAAAGGTATTTATTTTTGATGAAGTAACAAGTGGCTTAGATACAATTACTGAGAAGAAAGTGATTGATAATTTGATGAA
GCTAAAGGATAAGACAATTATCTTTATTGCGCATCGACTAGCAATTGCAGAACGGGCAGACAAGGTAGTTGTAATTGATC
ATGGTCAAATAGTTGAAGAAGGCAGCCACAGCGAATTGATGAGTAAGCATGGTTTTTACTATGACTTAGTGAAGGGATAG
ATGTTATTCAAATATAAATCCGTATACGTGCCACAAGTGGATGAGATGGATTGCGGCGTTGCTTGTCTAGCAATGATCTT
AAAGCAATATCATTCTCGCGTATCTTTAGCACATTTACGTCATGAAGCTCGTACTAATCTTGAAGGCACAACTGCTTTAG
GACTAGTGAAGACAGCACAAAAATTTAATTTCAAAACAGAAGCCGTAAAAGCAGATATGTCTTTATTTGATGAGAATAGT
ATTCAATATCCTTTTATTGCCCACGTCCTAAAACAAGGAGAACTACTTCATTATTACGTAGTTCTTAAAAATGCTAAGAA
TTATTTAGTAATTGCAGATCCTGATCCATCAGTTGGTGTAGTAAAGATGCCAAAAGACAAATTTGCTCAAGAATGGACTG
GTGTTGCACTCTTTATGGTTCCTAACGAAGACTTTGAACCAATCAAAGAAAAGAAGAATAATTTATGGTCTCTCTTTCCA
TATATGTTTAAACAAAAGCGGCTGATGATTAACATCATTTTAGCCGCTTTATTAATGACCATAATTAGTATCTGTAGTTC
ATATTTTGTTCAAGGAATAATTGATACTTACATTCCAGATGGAACCTATCAGACTCTTTCGATCTTAGCTGTTGGACTAT
TAATTGCTTATGTCTTTAATTCAATTTTTTCTTATGGACAGAATTTTTTATTAAATATTTTAGGTCAAAGATTAAGTATT
GATCTAAATCTGCGATACATCAGGCATATTTTTGAATTACCAATGGAATTCTTTGTAACAAGAAGAACGGGTGAAATTAC
TTCGCGTTTTTCTGATGCAAGTAGAATTATTGACGCTTTGGCAAGTACAGTTATTTCGCTCTTCTTAGACCTCTCAATTG
TGATTGTGATGGGATTAGTCTTAGCAGCACAAAATATGACATTATTTGGGATTACACTGTTAGCTTTGCCTATTTATGCA
GTTGTAATTCTAGGTTTTACTAAAAAGTTTGAAAAACTAAATAACGAACAAATGGAAAGTAATGCTGTTTTGAGTTCTTC
AGTTATTGAAGATATTCAAGGAATTGAAACTATTAAAGCTTTAAATAGTGAGAATACAAGATATAGAAGAATCGACAGTC
AGTTTGTAGATTACTTAAAGAAGTCATTTAAATATAGTAAGACTGAGAGTTTACAGACAGCACTCAAGACATTTATTCAA
TTATCTCTTAATGTAATTGTTCTTTGGGTTGGTGCAAAGATTGTAATGCAAGGACAATTGAGCATTGGTCAGTTAATGAC
GTTCAATGCATTGCTGGCATATTTCATTGATCCCTTGCAAAGTATTATTAATTTACAACCGCGACTTCAATCAGCTAGTG
TTGCTCAAAATCGATTAAATGAGGTCTATCAAGTAAAAAGTGAATTCAATCAGAAGGCTACTATTGAAGATCGTAAGCTC
CTAGAAGGAAATATTGAATATAAGAATGTGGATTATAGCTATGGTTATGGCACAGATGTCTTAAAAGATATTAATCTCAA
AATTAGCCAGGGCGAAAAATTAACGATTGTTGGAATGAGTGGTTCTGGAAAATCTACGATGGTTAAGTTGTTAGTAGATT
TCTTTTCGCCAAGTAAAGGTCAGGTTACATTAAATGGACATGCAACAAGTGAGATTGATAAGCATACGTTGCGGTCATAT
GTAAATTATGTACCTCAAACTCCATATATCTTTTCTGGAACAGTTAAAGAGAATTTGTTGTTAGGTTGTAGGCCAGATAT
CACTGAAGAAGATGTAATAAAGGCTTGTCAAATTGCTGAGATTGACCAAGAAATAGCTAATCTACCTTTGCAATTTGAAA
CAAAATTAGATGAAAATGCCAAAATTTTATCTGGTGGACAAAAACAAAGGTTAACTATTGCCCGGGCATTACTATCTCCT
GCAAAGGTATTTATTTTTGATGAAGTAACAAGTGGCTTAGATACAATTACTGAGAAGAAAGTGATTGATAATTTGATGAA
GCTAAAGGATAAGACAATTATCTTTATTGCGCATCGACTAGCAATTGCAGAACGGGCAGACAAGGTAGTTGTAATTGATC
ATGGTCAAATAGTTGAAGAAGGCAGCCACAGCGAATTGATGAGTAAGCATGGTTTTTACTATGACTTAGTGAAGGGATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comA | Streptococcus mitis NCTC 12261 |
57.725 |
99.026 |
0.572 |
| comA | Streptococcus mitis SK321 |
57.444 |
99.026 |
0.569 |
| comA | Streptococcus pneumoniae Rx1 |
57.303 |
99.026 |
0.567 |
| comA | Streptococcus pneumoniae D39 |
57.303 |
99.026 |
0.567 |
| comA | Streptococcus pneumoniae R6 |
57.303 |
99.026 |
0.567 |
| comA | Streptococcus pneumoniae TIGR4 |
57.163 |
99.026 |
0.566 |
| comA | Streptococcus gordonii str. Challis substr. CH1 |
55.478 |
99.026 |
0.549 |
| comA/nlmT | Streptococcus mutans UA159 |
53.748 |
98.331 |
0.529 |