Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   ACJWMD_RS02855 Genome accession   NZ_CP177182
Coordinates   556842..558722 (+) Length   626 a.a.
NCBI ID   WP_002886860.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD6060     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 551842..563722
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMD_RS02840 fmt 553814..554749 (+) 936 WP_002886857.1 methionyl-tRNA formyltransferase -
  ACJWMD_RS02845 rsmB 554739..556061 (+) 1323 WP_002886858.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ACJWMD_RS02850 - 556105..556842 (+) 738 WP_002886859.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACJWMD_RS02855 stkP/pknB 556842..558722 (+) 1881 WP_002886860.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ACJWMD_RS02860 - 558868..559032 (+) 165 WP_411888504.1 hypothetical protein -
  ACJWMD_RS02865 - 559038..559556 (+) 519 WP_411888505.1 potassium channel family protein -
  ACJWMD_RS02870 liaF 559720..560418 (+) 699 WP_002886862.1 cell wall-active antibiotics response protein LiaF -
  ACJWMD_RS02875 - 560415..561425 (+) 1011 WP_002886863.1 sensor histidine kinase -
  ACJWMD_RS02880 - 561415..562059 (+) 645 WP_002884791.1 response regulator transcription factor -
  ACJWMD_RS02895 rimM 562754..563272 (+) 519 WP_002884411.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 626 a.a.        Molecular weight: 68145.84 Da        Isoelectric Point: 7.6981

>NTDB_id=1086006 ACJWMD_RS02855 WP_002886860.1 556842..558722(+) (stkP/pknB) [Streptococcus salivarius strain MRD6060]
MIQVGKLFAGRYRILKAIGRGGMADVYLANDLILDNEKVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEILSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGRIPYDGDSAVTIALQHFQKPLPSILAENHNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLYPSHSRDAKVVFDDMTDTKTLPKVTPVPSVSSEKKATAKSSESKQAV
SKQPRKNSTLAKNKKKKKKKSFFSTSLKVFLGLVFIGIIIFAYLVFTNPDSTQVPNVVGQELSTAQTKIEGAGFKVGEVK
EVEDDSVDTGKVVKTDPTAGTTRKEGSSIDIYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEE
GEILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGAKLDKDKVPSST
EVLYQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTESTSSSTETPTEATHTDQQ

Nucleotide


Download         Length: 1881 bp        

>NTDB_id=1086006 ACJWMD_RS02855 WP_002886860.1 556842..558722(+) (stkP/pknB) [Streptococcus salivarius strain MRD6060]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAAGCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATCTTGGATAATGAGAAAGTGGCCATTAAGGTGCTTCGTACTAATTATCAAACCGATCAGGTAG
CTGTGGCACGTTTCCAGCGTGAAGCACGTGCCATGGCAGAACTCAGTCATCCCAATATCGTTGCAATCCGAGACATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTACGTGGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCACC
ACTTTCTAACCAAGATGTTGTGCGTATTATGGGAGAGATTCTTTCTGCCATGACTCTTGCCCATCAAAAGGGTATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTAGGGCCAAAGTTACAGACTTCGGGATTGCGGTTGCC
TTTGCAGAGACTAGTTTGACTCAAACCAATTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCGCGTGGATC
TAAAGCAACTATCCAAAGTGATATCTATGCTATGGGTATCATGCTCTTTGAAATGTTGACAGGGCGTATTCCATATGATG
GTGATAGTGCAGTTACCATCGCTCTTCAGCATTTCCAAAAACCATTACCATCAATCTTGGCTGAGAATCATAATGTTCCT
CAGGCATTGGAAAATGTGGTTATTCGAGCGACAGCTAAAAAGCTTGAAAATCGTTATAACAGTACTTTGGAAATGAGCCG
AGATTTAGTAACTAGCTTATATCCTAGCCATAGCCGTGATGCGAAGGTAGTCTTTGATGACATGACGGATACTAAGACTT
TGCCTAAGGTTACTCCAGTTCCGTCAGTAAGCTCTGAGAAAAAGGCAACTGCCAAGTCATCAGAGTCAAAACAAGCTGTA
AGTAAGCAACCAAGGAAAAATTCAACACTAGCTAAGAATAAAAAGAAGAAAAAAAAGAAAAGCTTTTTCTCGACATCACT
CAAGGTATTCCTGGGGTTGGTCTTTATCGGGATTATCATTTTTGCCTATTTGGTATTTACCAACCCTGATAGTACTCAGG
TGCCTAACGTGGTCGGTCAAGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGTGAAGTTAAG
GAAGTGGAAGATGACTCTGTCGATACAGGCAAGGTCGTAAAGACTGATCCTACAGCTGGAACCACACGAAAAGAAGGATC
AAGCATTGATATCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAAGGTAAAAATTATAAGGATGCCA
TTGAGGATTTAACTTCGAATTATGGCGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAG
GGAGAAATCCTATCTCAAAGTCCAGGTAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCCAAGATTAAGTTCCGTGT
GGCAACTCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGA
GTATCTCAAGTAGTAGCATCGAGTATCATGACTATAATACTGGTGCTAAGTTAGACAAGGATAAGGTTCCTAGCAGTACA
GAGGTCCTTTATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGCAAG
TTCAAGCCTACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGAAAGCACAAGCTCTAGTA
CTGAAACACCGACAGAGGCTACTCACACAGACCAACAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(373-434)

PASTA domain (PASTA)

(443-507)

PASTA domain (PASTA)

(513-582)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

93.142

100

0.933
  pknB Streptococcus mutans UA159

65.993

86.901

0.573
  stkP Streptococcus pneumoniae TIGR4

51.286

93.131

0.478
  stkP Streptococcus pneumoniae D39

51.115

93.131

0.476
  stkP Streptococcus pneumoniae R6

51.115

93.131

0.476
  stkP Streptococcus pneumoniae Rx1

50.943

93.131

0.474

Multiple sequence alignment