Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACJWMD_RS00955 Genome accession   NZ_CP177182
Coordinates   170055..170804 (+) Length   249 a.a.
NCBI ID   WP_002886435.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD6060     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 165055..175804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMD_RS00935 - 166069..166809 (-) 741 WP_002886432.1 amino acid ABC transporter ATP-binding protein -
  ACJWMD_RS00940 - 166809..168356 (-) 1548 WP_002886433.1 ABC transporter substrate-binding protein/permease -
  ACJWMD_RS00945 - 168562..169416 (+) 855 WP_002883622.1 undecaprenyl-diphosphate phosphatase -
  ACJWMD_RS00950 - 169476..169847 (-) 372 WP_002886434.1 DUF3021 family protein -
  ACJWMD_RS00955 mecA 170055..170804 (+) 750 WP_002886435.1 adaptor protein MecA Regulator
  ACJWMD_RS00960 - 170808..171965 (+) 1158 WP_002886436.1 glycosyltransferase family 4 protein -
  ACJWMD_RS00965 sufC 172127..172897 (+) 771 WP_411888499.1 Fe-S cluster assembly ATPase SufC -
  ACJWMD_RS00970 sufD 172934..174196 (+) 1263 WP_002886437.1 Fe-S cluster assembly protein SufD -
  ACJWMD_RS00975 - 174250..175140 (+) 891 Protein_141 aminotransferase class V-fold PLP-dependent enzyme -
  ACJWMD_RS00980 - 175142..175285 (+) 144 Protein_142 SseB family protein -
  ACJWMD_RS00985 - 175287..175622 (+) 336 Protein_143 aminotransferase class V-fold PLP-dependent enzyme -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29072.63 Da        Isoelectric Point: 4.0148

>NTDB_id=1085983 ACJWMD_RS00955 WP_002886435.1 170055..170804(+) (mecA) [Streptococcus salivarius strain MRD6060]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEENIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEDDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=1085983 ACJWMD_RS00955 WP_002886435.1 170055..170804(+) (mecA) [Streptococcus salivarius strain MRD6060]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGATCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGATGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTAAAGGCTCT
TGAGGGTAATTTTATGGACAAGGGTGACATCGAAGCACACCATAAGCTTGAAGAGCTTGAAAAGACCTTGGAAGAGGTTG
ATAAAGCTATGACAGAGCCTACTAAGGAAGTGGCTGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCCTTT
TCTGATTTTGATCAAGTGGTGACTTTTACGCAAGGTTTGAAGGATGTACCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GGATGTCTACTACATGACGATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTGCCTACCTACAAGAGCATGCAACAATCTTGATGGAAGATGATGCTTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.976

100

0.94
  mecA Streptococcus thermophilus LMG 18311

93.173

100

0.932
  mecA Streptococcus mutans UA159

60.246

97.992

0.59
  mecA Streptococcus pneumoniae Rx1

47.39

100

0.474
  mecA Streptococcus pneumoniae D39

47.39

100

0.474
  mecA Streptococcus pneumoniae R6

47.39

100

0.474
  mecA Streptococcus pneumoniae TIGR4

47.39

100

0.474

Multiple sequence alignment