Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACJWMC_RS01650 Genome accession   NZ_CP177181
Coordinates   313080..313769 (+) Length   229 a.a.
NCBI ID   WP_002883757.1    Uniprot ID   A0AB33ZE44
Organism   Streptococcus salivarius strain MRD1919     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 308080..318769
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMC_RS01625 - 308383..309213 (+) 831 WP_002889956.1 energy-coupling factor transporter transmembrane component T family protein -
  ACJWMC_RS01630 - 309302..309973 (-) 672 WP_002889958.1 potassium channel family protein -
  ACJWMC_RS01635 - 310013..311307 (-) 1295 Protein_283 TrkH family potassium uptake protein -
  ACJWMC_RS01640 rsmG 311376..312089 (-) 714 WP_002889960.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  ACJWMC_RS01645 - 312388..312924 (+) 537 WP_002889961.1 DUF177 domain-containing protein -
  ACJWMC_RS01650 covR 313080..313769 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  ACJWMC_RS01655 covS 313766..315295 (+) 1530 WP_002889963.1 HAMP domain-containing histidine kinase Regulator
  ACJWMC_RS01660 nrdR 315417..315896 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  ACJWMC_RS01665 - 315893..317068 (+) 1176 WP_002889965.1 DnaD domain protein -
  ACJWMC_RS01670 dnaI 317072..317974 (+) 903 WP_002889966.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26501.51 Da        Isoelectric Point: 4.6354

>NTDB_id=1085924 ACJWMC_RS01650 WP_002883757.1 313080..313769(+) (covR) [Streptococcus salivarius strain MRD1919]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1085924 ACJWMC_RS01650 WP_002883757.1 313080..313769(+) (covR) [Streptococcus salivarius strain MRD1919]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGTGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGCTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCCCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGTGGTGCTGATGACTATATTGTAAAACCTTTTGCGATTGA
AGAACTATTGGCACGTATTCGTGCAACCTTCCGTCGCCAAGATATCGAAGCTGCTAAGAATGCACCAGCTAAAGCGTCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCAATCGAAACAAACGTTGTAGATGTTTATATTCGTTACTTGCGTGGAAAAATCGATGTTCCAGGTAAGGAAT
CATACATTCAAACAGTGCGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

100

100

1
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

45.923

100

0.467
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445

Multiple sequence alignment