Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   ACJWMC_RS01655 Genome accession   NZ_CP177181
Coordinates   313766..315295 (+) Length   509 a.a.
NCBI ID   WP_002889963.1    Uniprot ID   J7SI89
Organism   Streptococcus salivarius strain MRD1919     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 308766..320295
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMC_RS01630 - 309302..309973 (-) 672 WP_002889958.1 potassium channel family protein -
  ACJWMC_RS01635 - 310013..311307 (-) 1295 Protein_283 TrkH family potassium uptake protein -
  ACJWMC_RS01640 rsmG 311376..312089 (-) 714 WP_002889960.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  ACJWMC_RS01645 - 312388..312924 (+) 537 WP_002889961.1 DUF177 domain-containing protein -
  ACJWMC_RS01650 covR 313080..313769 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  ACJWMC_RS01655 covS 313766..315295 (+) 1530 WP_002889963.1 HAMP domain-containing histidine kinase Regulator
  ACJWMC_RS01660 nrdR 315417..315896 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  ACJWMC_RS01665 - 315893..317068 (+) 1176 WP_002889965.1 DnaD domain protein -
  ACJWMC_RS01670 dnaI 317072..317974 (+) 903 WP_002889966.1 primosomal protein DnaI -
  ACJWMC_RS01675 der 318080..319390 (+) 1311 WP_037597430.1 ribosome biogenesis GTPase Der -
  ACJWMC_RS01680 - 319455..320084 (+) 630 WP_037597433.1 hypothetical protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58068.44 Da        Isoelectric Point: 5.1853

>NTDB_id=1085925 ACJWMC_RS01655 WP_002889963.1 313766..315295(+) (covS) [Streptococcus salivarius strain MRD1919]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLFSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=1085925 ACJWMC_RS01655 WP_002889963.1 313766..315295(+) (covS) [Streptococcus salivarius strain MRD1919]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTGTTTTCTCGGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAA
ATAACACAATTTCGAAAGTTGTTACTTATATCGAAAAGGACTGGGATTCTGATGAAGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCGCCTAAAAATATCTATGCATCAATCATTAATGGTGTGCTTTCTGAAAAGCACTCTTTGGATGGTCA
AGTTGCAATTTCTAATAAATTATTTTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAAAACACAGACTCTCCTCCAGGCATGTCTGAAGTAAACAAACTGAAGTCAGTGTCCTATAAAGGAAAGCGTGGTTTC
TTACTACAAGTTCCAATTTACGGTAAGGATAAAAAGACCATCGTTGGTTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTGAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTTCTAGTTATCGCAGCAACTG
TGGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACGCCGATTGCGGTTATTAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAGGAAAGTCTTGAGGCTGCCAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGACATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCATAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGCGTCTTGCACGAAGACTACCAATTCTATCTCA
ATGATTTCGAGAGCTCAGAGCGCCCTGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTGCAAGTGCA
AGATAATGGTGAAGGGATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTACCGTTCAGATAAGGCACGTAACC
GTACGACAACGCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTACCAAATTGTGGAAGCTTATCGCTGCCGTATCGAT
GTTAGTTCTGAACTCGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCGGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SI89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

99.607

100

0.996

Multiple sequence alignment