Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACJWMC_RS01045 Genome accession   NZ_CP177181
Coordinates   191770..192519 (+) Length   249 a.a.
NCBI ID   WP_037597351.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD1919     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 186770..197519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMC_RS01025 - 187785..188525 (-) 741 WP_002886432.1 amino acid ABC transporter ATP-binding protein -
  ACJWMC_RS01030 - 188525..190072 (-) 1548 WP_037597348.1 ABC transporter substrate-binding protein/permease -
  ACJWMC_RS01035 - 190278..191132 (+) 855 WP_002889764.1 undecaprenyl-diphosphate phosphatase -
  ACJWMC_RS01040 - 191192..191563 (-) 372 WP_002889766.1 DUF3021 family protein -
  ACJWMC_RS01045 mecA 191770..192519 (+) 750 WP_037597351.1 adaptor protein MecA Regulator
  ACJWMC_RS01050 - 192523..193680 (+) 1158 WP_002889771.1 glycosyltransferase family 4 protein -
  ACJWMC_RS01055 sufC 193842..194612 (+) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  ACJWMC_RS01060 sufD 194649..195911 (+) 1263 WP_002889773.1 Fe-S cluster assembly protein SufD -
  ACJWMC_RS01065 - 195965..197197 (+) 1233 WP_002889774.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29085.67 Da        Isoelectric Point: 4.0356

>NTDB_id=1085917 ACJWMC_RS01045 WP_037597351.1 191770..192519(+) (mecA) [Streptococcus salivarius strain MRD1919]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEENIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGNVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=1085917 ACJWMC_RS01045 WP_037597351.1 191770..192519(+) (mecA) [Streptococcus salivarius strain MRD1919]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTACACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGCGGGATGCTGAGCTTCCGGGTCACGCCACGCAAGGACCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAACGATTTGTCAGATATGGACGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTCAAGGCTCT
TGAAGGTAACTTTATGGACAAGGGGGATATCGAAGCACACCATAAGCTCGAAGAACTTGAGAAGACCTTGGAAGAAGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGGCTGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTACACAAGGCTTGAAGGATGTACCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GAATGTCTACTATATGACAATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCAAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTGCCTACCTGCAAGAGCATGCAACAATTTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.976

100

0.94
  mecA Streptococcus thermophilus LMG 18311

93.173

100

0.932
  mecA Streptococcus mutans UA159

59.836

97.992

0.586
  mecA Streptococcus pneumoniae Rx1

47.39

100

0.474
  mecA Streptococcus pneumoniae D39

47.39

100

0.474
  mecA Streptococcus pneumoniae R6

47.39

100

0.474
  mecA Streptococcus pneumoniae TIGR4

47.39

100

0.474

Multiple sequence alignment